Tavasolian, F.; Faculty of Medicine, Tarbiat Modares University of Medical Science, Tehran, Iran
Abdollahi, E.; Student Research Committee, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
Rezaei, R.; Clinical Research Unit, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Momtazi-borojeni, A. A.; Nanotechnology Research Center, Department of Medical Biotechnology, Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Henrotin, Yves ; Université de Liège - ULiège > Département des sciences de la motricité > Unité de recherche sur l'os et le cartilage (U.R.O.C.)
Sahebkar, A.; Biotechnology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Langue du document :
Anglais
Titre :
Altered Expression of MicroRNAs in Rheumatoid Arthritis
Abdollahi E, Tavasolian F, Ghasemi N, Mirghanizadeh SA, Azizi M, Ghoryani M, Samadi M. 2015. Association between lower frequency of R381Q variant (rs11209026) in IL-23 receptor gene and increased risk of recurrent spontaneous abortion (RSA). J Immunotoxicol 12:317–321.
Abdollahi E, Tavasolian F, Momtazi-Borojeni AA, Samadi M, Rafatpanah H. 2016. Protective role of R381Q (rs11209026) polymorphism in IL-23R gene in immune-mediated diseases: A comprehensive review. J Immunotoxicol 13:286–300.
Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO, 3rd, Birnbaum NS, Burmester GR, Bykerk VP, Cohen MD, Combe B, Costenbader KH, Dougados M, Emery P, Ferraccioli G, Hazes JM, Hobbs K, Huizinga TW, Kavanaugh A, Kay J, Kvien TK, Laing T, Mease P, Menard HA, Moreland LW, Naden RL, Pincus T, Smolen JS, Stanislawska-Biernat E, Symmons D, Tak PP, Upchurch KS, Vencovsky J, Wolfe F, Hawker G. 2010a. 2010 Rheumatoid arthritis classification criteria: An American college of rheumatology/European league against rheumatism collaborative initiative. Arthritis Rheum 62:2569–2581.
Aletaha D, Neogi T, Silman AJ, Funovits J, Felson DT, Bingham CO, Birnbaum NS, Burmester GR, Bykerk VP, Cohen MD. 2010b. 2010 Rheumatoid arthritis classification criteria: An American college of rheumatology/European league against rheumatism collaborative initiative. Arthritis Rheum 62:2569–2581.
Alsaleh G, Suffert G, Semaan N, Juncker T, Frenzel L, Gottenberg J-E, Sibilia J, Pfeffer S, Wachsmann D. 2009. Bruton's tyrosine kinase is involved in miR-346-related regulation of IL-18 release by lipopolysaccharide-activated rheumatoid fibroblast-like synoviocytes. J Immunol 182:5088–5097.
Baker JF, Tan YK, Conaghan PG. 2015. Monitoring in established RA: Role of imaging and soluble biomarkers. Best Pract Res Clin Rheumatol 29:566–579.
Ceribelli A, Yao B, Dominguez-Gutierrez PR, Nahid MA, Satoh M, Chan EK. 2011. MicroRNAs in systemic rheumatic diseases. Arthritis Res Therapy 13:1.
Chatzikyriakidou A, Voulgari PV, Georgiou I, Drosos AA. 2012. MiRNAs and related polymorphisms in rheumatoid arthritis susceptibility. Autoimmun Rev 11:636–641.
Cimmino A, Calin GA, Fabbri M, Iorio MV, Ferracin M, Shimizu M, Wojcik SE, Aqeilan RI, Zupo S, Dono M. 2005. MiR-15 and miR-16 induce apoptosis by targeting BCL2. Proc Natl Acad Sci USA 102:13944–13949.
Dahlén E, Barchan K, Herrlander D, Höjman P, Karlsson M, Ljung L, Andersson M, Bäckman E, Hager A-CM, Walse B. 2008. Development of interleukin-1 receptor antagonist mutants with enhanced antagonistic activity in vitro and improved therapeutic efficacy in collagen-induced arthritis. J Immunotoxicol 5:189–199.
De Rycke L, Peene I, Hoffman I, Kruithof E, Union A, Meheus L, Lebeer K, Wyns B, Vincent C, Mielants H. 2004. Rheumatoid factor and anticitrullinated protein antibodies in rheumatoid arthritis: Diagnostic value, associations with radiological progression rate, and extra-articular manifestations. Ann Rheum Dis 63:1587–1593.
Dong L, Wang X, Tan J, Li H, Qian W, Chen J, Chen Q, Wang J, Xu W, Tao C. 2014. Decreased expression of microRNA-21 correlates with the imbalance of Th17 and Treg cells in patients with rheumatoid arthritis. J Cell Mol Med 18:2213–2224.
Duroux-Richard I, Jorgensen C, Apparailly F. 2012. What do microRNAs mean for rheumatoid arthritis? Arthritis Rheum 64:11–20.
Escobar T, Yu C-R, Muljo SA, Egwuagu CE. 2013. STAT3 activates miR-155 in th17 cells and acts in concert to promote experimental autoimmune UveitisSTAT3/miR-155 axis promotes th17 development and EAU. Invest Ophthalmol Vis Sci 54:4017–4025.
Escobar TM, Kanellopoulou C, Kugler DG, Kilaru G, Nguyen CK, Nagarajan V, Bhairavabhotla RK, Northrup D, Zahr R, Burr P. 2014. MiR-155 activates cytokine gene expression in Th17 cells by regulating the DNA-binding protein Jarid2 to relieve polycomb-mediated repression. Immunity 40:865–879.
Faraoni I, Antonetti FR, Cardone J, Bonmassar E. 2009. MiR-155 gene: A typical multifunctional microRNA. Biochimica et Biophysica Acta 1792:497–505.
Firestein GS, Yeo M, Zvaifler NJ. 1995. Apoptosis in rheumatoid arthritis synovium. J Clin Invest 96:1631.
Garzon R, Marcucci G, Croce CM. 2010. Targeting microRNAs in cancer: Rationale, strategies and challenges. Nat Rev Drug Disc 9:775–789.
Gregersen PK, Batliwalla F. 2005. PTPN22 and rheumatoid arthritis: Gratifying replication. Arthritis Rheum 52:1952–1955.
Horwitz DA, Zheng SG, Wang J, Gray JD. 2008. Critical role of IL-2 and TGF-β in generation, function and stabilization of Foxp3+ CD4+ Treg. Eur J Immunol 38:912–915.
Klein K, Ospelt C, Gay S. 2012. Epigenetic contributions in the development of rheumatoid arthritis. Arthritis Res Therapy 14:1.
Kohlhaas S, Garden OA, Scudamore C, Turner M, Okkenhaug K, Vigorito E. 2009. Cutting edge: The Foxp3 target miR-155 contributes to the development of regulatory T cells. J Immunol 182:2578–2582.
Kurowska-Stolarska M, Alivernini S, Ballantine LE, Asquith DL, Millar NL, Gilchrist DS, Reilly J, Ierna M, Fraser AR, Stolarski B. 2011. MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis. Proc Natl Acad Sci USA 108:11193–11198.
Lee YK, Turner H, Maynard CL, Oliver JR, Chen D, Elson CO, Weaver CT. 2009. Late developmental plasticity in the T helper 17 lineage. Immunity 30:92–107.
Li G, Yu M, Lee W-W, Tsang M, Krishnan E, Weyand CM, Goronzy JJ. 2012. Decline in miR-181a expression with age impairs T cell receptor sensitivity by increasing DUSP6 activity. Nat Med 18:1518–1524.
Li J, Wan Y, Guo Q, Zou L, Zhang J, Fang Y, Zhang J, Zhang J, Fu X, Liu H. 2010. Altered microRNA expression profile with miR-146a upregulation in CD4+ T cells from patients with rheumatoid arthritis. Arthritis Res Therapy 12:1.
Li X, Tian F, Wang F. 2013. Rheumatoid arthritis-associated microRNA-155 targets SOCS1 and upregulates TNF-α and IL-1β in PBMCs. Int J Mol Sci 14:23910–23921.
Lu L-F, Boldin MP, Chaudhry A, Lin L-L, Taganov KD, Hanada T, Yoshimura A, Baltimore D, Rudensky AY. 2010. Function of miR-146a in controlling Treg cell-mediated regulation of Th1 responses. Cell 142:914–929.
MacGregor AJ, Snieder H, Rigby AS, Koskenvuo M, Kaprio J, Aho K, Silman AJ. 2000. Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins. Arthritis Rheum 43:30.
Markusse IM, Dirven L, van den Broek M, Bijkerk C, Han KH, Ronday HK, Bolce R, Sasso EH, Kerstens PJ, Lems WF, Huizinga TW, Allaart CF. 2014. A multibiomarker disease activity score for rheumatoid arthritis predicts radiographic joint damage in the best study. J Rheumatol 41:2114–2119.
McGeachy MJ, Bak-Jensen KS, Chen Y, Tato CM, Blumenschein W, McClanahan T, Cua DJ. 2007. TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell-mediated pathology. Nat Immunol 8:1390–1397.
Mendell JT. 2008. MiRiad roles for the miR-17-92 cluster in development and disease. Cell 133:217–222.
Michou L, Lasbleiz S, Rat A-C, Migliorini P, Balsa A, Westhovens R, Barrera P, Alves H, Pierlot C, Glikmans E. 2007. Linkage proof for PTPN22, a rheumatoid arthritis susceptibility gene and a human autoimmunity gene. Proc Natl Acad Sci 104:1649–1654.
Mieliauskaite D, Venalis P, Dumalakiene I, Venalis A, Distler J. 2009. Relationship between serum levels of TGF-β1 and clinical parameters in patients with rheumatoid arthritis and Sjögren's syndrome secondary to rheumatoid arthritis: Brief definite report. Autoimmunity 42:356–358.
Mu N, Gu J, Huang T, Zhang C, Shu Z, Li M, Hao Q, Li W, Zhang W, Zhao J. 2016. A novel NF-κB/YY1/microRNA-10a regulatory circuit in fibroblast-like synoviocytes regulates inflammation in rheumatoid arthritis. Sci Rep 6:20059.
Murata K, Furu M, Yoshitomi H, Ishikawa M, Shibuya H, Hashimoto M, Imura Y, Fujii T, Ito H, Mimori T. 2013. Comprehensive microRNA analysis identifies miR-24 and miR-125a-5p as plasma biomarkers for rheumatoid arthritis. PLoS ONE 8:e69118.
Murata K, Yoshitomi H, Tanida S, Ishikawa M, Nishitani K, Ito H, Nakamura T. 2010. Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis. Arthritis Res Therapy 12:1.
Nakamachi Y, Kawano S, Takenokuchi M, Nishimura K, Sakai Y, Chin T, Saura R, Kurosaka M, Kumagai S. 2009. MicroRNA-124a is a key regulator of proliferation and monocyte chemoattractant protein 1 secretion in fibroblast-like synoviocytes from patients with rheumatoid arthritis. Arthritis Rheum 60:1294–1304.
Nakasa T, Miyaki S, Okubo A, Hashimoto M, Nishida K, Ochi M, Asahara H. 2008. Expression of microRNA-146 in rheumatoid arthritis synovial tissue. Arthritis Rheum 58:1284–1292.
Nakasa T, Miyaki S, Okubo A, Hashimoto M, Nishida K, Ochi M, Asahara H. 2008. Expression of microRNA-146 in rheumatoid arthritis synovial tissue. Arthritis Rheum 58:1284–1292.
Niederer F, Trenkmann M, Ospelt C, Karouzakis E, Neidhart M, Stanczyk J, Kolling C, Gay RE, Detmar M, Gay S. 2012. Down-regulation of microRNA-34a* in rheumatoid arthritis synovial fibroblasts promotes apoptosis resistance. Arthritis Rheum 64:1771–1779.
Nishimura K, Sugiyama D, Kogata Y, Tsuji G, Nakazawa T, Kawano S, Saigo K, Morinobu A, Koshiba M, Kuntz KM. 2007. Meta-analysis: Diagnostic accuracy of anti-cyclic citrullinated peptide antibody and rheumatoid factor for rheumatoid arthritis. Anna Intern Med 146:797–808.
O'Connell RM, Rao DS, Baltimore D. 2012. MicroRNA regulation of inflammatory responses. Ann Rev Immunol 30:295–312.
Padyukov L, Silva C, Stolt P, Alfredsson L, Klareskog L. 2004. A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritis. Arthritis Rheum 50:3085–3092.
Paleolog EM. 2002. Angiogenesis in rheumatoid arthritis. Arthritis Res Therapy 4:1.
Park H-J, Kim D-H, Lim S-H, Kim W-J, Youn J, Choi Y-S, Choi J-M. 2014. Insights into the role of follicular helper T cells in autoimmunity. Immune Network 14:21–29.
Pauley KM, Satoh M, Chan AL, Bubb MR, Reeves WH, Chan EK. 2008a. Upregulated miR-146 a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients. Arthritis Res Therapy 10:1.
Pauley KM, Satoh M, Chan AL, Bubb MR, Reeves WH, Chan EK. 2008b. Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients. Arthritis Res Ther 10:R101.
Philippe L, Alsaleh G, Bahram S, Pfeffer S, Georgel P. 2013. The miR-17–92 cluster: A key player in the control of inflammation during rheumatoid arthritis. Front Immunol 4:70.
Philippe L, Alsaleh G, Suffert G, Meyer A, Georgel P, Sibilia J, Wachsmann D, Pfeffer S. 2012. TLR2 expression is regulated by microRNA miR-19 in rheumatoid fibroblast-like synoviocytes. J Immunol 188:454–461.
Pope RM. 2002. Apoptosis as a therapeutic tool in rheumatoid arthritis. Nat Rev Immunol 2:527–535.
Sakaguchi S, Benham H, Cope AP, Thomas R. 2012. T-cell receptor signaling and the pathogenesis of autoimmune arthritis: Insights from mouse and man. Immunol Cell Biol 90:277–287.
Schöler N, Langer C, Döhner H, Buske C, Kuchenbauer F. 2010. Serum microRNAs as a novel class of biomarkers: A comprehensive review of the literature. Exp Hematol 38:1126–1130.
Shibuya H, Nakasa T, Adachi N, Nagata Y, Ishikawa M, Deie M, Suzuki O, Ochi M. 2013. Overexpression of microRNA-223 in rheumatoid arthritis synovium controls osteoclast differentiation. Mod Rheumatol 23:674–685.
Singh UP, Murphy AE, Enos RT, Shamran HA, Singh NP, Guan H, Hegde VL, Fan D, Price RL, Taub DD. 2014. MiR-155 deficiency protects mice from experimental colitis by reducing T helper type 1/type 17 responses. Immunology 143:478–489.
Smigielska-Czepiel K, van den Berg A, Jellema P, van der Lei RJ, Bijzet J, Kluiver J, Boots AMH, Brouwer E, Kroesen B-J. 2014. Comprehensive analysis of miRNA expression in T-cell subsets of rheumatoid arthritis patients reveals defined signatures of naive and memory Tregs. Genes Immun 15:115–125.
Stanczyk J, Ospelt C, Karouzakis E, Filer A, Raza K, Kolling C, Gay R, Buckley CD, Tak PP, Gay S. 2011. Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation. Arthritis Rheum 63:373–381.
Stanczyk J, Pedrioli DM, Brentano F, Sanchez-Pernaute O, Kolling C, Gay RE, Detmar M, Gay S, Kyburz D. 2008. Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis. Arthritis Rheum 58:1001–1009.
Starczynowski DT, Kuchenbauer F, Argiropoulos B, Sung S, Morin R, Muranyi A, Hirst M, Hogge D, Marra M, Wells RA. 2010. Identification of miR-145 and miR-146a as mediators of the 5q-syndrome phenotype. Nat Med 16:49–58.
Taganov KD, Boldin MP, Chang K-J, Baltimore D. 2006. NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses. Proc Natl Acad Sci USA 103:12481–12486.
Takahashi H, Kanno T, Nakayamada S, Hirahara K, Sciumè G, Muljo SA, Kuchen S, Casellas R, Wei L, Kanno Y. 2012. TGF-[beta] and retinoic acid induce the microRNA miR-10a, which targets Bcl-6 and constrains the plasticity of helper T cells. Nat Immunol 13:587–595.
Tanzer A, Stadler PF. 2004. Molecular evolution of a microRNA cluster. J Mol Biol 339:327–335.
Tavasolian F, Abdollahi E, Samadi M. 2014. Association of the IL4R single-nucleotide polymorphism I50V with recurrent spontaneous abortion (RSA). J Assist Reprod Genet 31:851–856.
Taylor PC. 2002. VEGF and imaging of vessels in rheumatoid arthritis. Arthritis Res Therapy 4:1.
Thai T-H, Calado DP, Casola S, Ansel KM, Xiao C, Xue Y, Murphy A, Frendewey D, Valenzuela D, Kutok JL. 2007. Regulation of the germinal center response by microRNA-155. Science 316:604–608.
Thomson DW, Bracken CP, Goodall GJ. 2011. Experimental strategies for microRNA target identification. Nucleic Acids Res 39:6845–6853.
Trenkmann M, Brock M, Gay RE, Michel BA, Gay S, Huber LC. 2013. Tumor necrosis factor α-Induced MicroRNA-18a activates rheumatoid arthritis synovial fibroblasts through a feedback loop in NF-κB signaling. Arthritis Rheum 65:916–927.
van Rooij E. 2011. The art of microRNA research. Circ Res 108:219–234.
Ventura A, Young AG, Winslow MM, Lintault L, Meissner A, Erkeland SJ, Newman J, Bronson RT, Crowley D, Stone JR. 2008. Targeted deletion reveals essential and overlapping functions of the miR-17–92 family of miRNA clusters. Cell 132:875–886.
Vigorito E, Perks KL, Abreu-Goodger C, Bunting S, Xiang Z, Kohlhaas S, Das PP, Miska EA, Rodriguez A, Bradley A. 2007. MicroRNA-155 regulates the generation of immunoglobulin class-switched plasma cells. Immunity 27:847–859.
Wang L, Song G, Tan W, Qi M, Zhang L, Chan J, Yu J, Han J, Han B. 2015. MiR-573 inhibits prostate cancer metastasis by regulating epithelial-mesenchymal transition. Oncotarget 6:35978.
Wang L, Song G, Zheng Y, Wang D, Dong H, Pan J, Chang X. 2016. MiR-573 is a negative regulator in the pathogenesis of rheumatoid arthritis. Cell Mol Immunol 13:839–849.
Wei M, Duan D. 2016. Efficacy and safety of monoclonal antibodies targeting interleukin-17 pathway for inflammatory arthritis: A meta-analysis of randomized controlled clinical trials. Drug Des Devel Ther 10:2771–2777.
Weyand CM, Goronzy JJ. 2017. Immunometabolism in early and late stages of rheumatoid arthritis. Nat Rev Rheumatol 13:291–301.
Wu W, He C, Liu C, Cao AT, Xue X, Evans-Marin HL, Sun M, Fang L, Yao S, Pinchuk IV. 2015. MiR-10a inhibits dendritic cell activation and Th1/Th17 cell immune responses in IBD. Gut 64:1755–1764.
Yao R, Ma Y-L, Liang W, Li H-H, Ma Z-J, Yu X, Liao Y-H. 2012. MicroRNA-155 modulates Treg and Th17 cells differentiation and Th17 cell function by targeting SOCS1. PLoS ONE 7:e46082.
Yao R, Ma Y, Du Y, Liao M, Li H, Liang W, Yuan J, Yu X, Xiao H, Liao Y. 2011. The altered expression of inflammation-related microRNAs with microRNA-155 expression correlates with Th17 differentiation in patients with acute coronary syndrome. Cell Mol Immunol 8:486–495.
Zhao X-D, Zhang W, Liang H-J, Ji W-Y. 2013. Overexpression of miR-155 promotes proliferation and invasion of human laryngeal squamous cell carcinoma via targeting SOCS1 and STAT3. PLoS ONE 8:e56395.
Zhou Q, Haupt S, Kreuzer JT, Hammitzsch A, Proft F, Neumann C, Leipe J, Witt M, Schulze-Koops H, Skapenko A. 2015. Decreased expression of miR-146a and miR-155 contributes to an abnormal Treg phenotype in patients with rheumatoid arthritis. Ann Rheum Dis 74:1265–1274.
Zhu S, Pan W, Song X, Liu Y, Shao X, Tang Y, Liang D, He D, Wang H, Liu W. 2012. The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3, and IKK-[alpha]. Nat Med 18:1077–1086.
Zhu S, Pan W, Song X, Liu Y, Shao X, Tang Y, Liang D, He D, Wang H, Liu W, Shi Y, Harley JB, Shen N, Qian Y. 2012. The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3, and IKK-alpha. Nat Med 18:1077–1086.
