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20 November 2017
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Platelet-rich plasma versus hyaluronic acid to treat tendinopathies
Kaux, Jean-François  ; Robertjot, Mathieu; SAMSON, Antoine  et al.
2017 • In European Journal of Sports Medicine, 5 (Supplement 1), p. 21-22
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Abstract :
[en] INTRODUCTION: The treatment of patellar tendinopathies could be difficult. This is the reason why new treatments have been developed, among which platelet rich plasma (PRP) injections. Some clinical series have previously evaluated the effect of PRP in the treatment of proximal patellar tendinopathies. Recent systematic review concluded that PRP could be recommend as a treatment in such indication (1). Recently, the viscoelastic properties of hyaluronic acid (HA) on liquid connective tissue have been proposed for the treatment of tendinopathies (2). Some fundamental studies show encouraging results on HA’s ability to promote tendon gliding and reduce adhesion as well as to improve tendon architectural organisation. Some observations also support its use in a clinical setting to improve pain and function. PURPOSE: We aimed to compare the effect of PRP injection versus two injections of HA after three months on patients who have a proximal patellar tendinopathy. METHODS: Thirtythree sportsmen with proximal patellar tendinopathies being not relieved after minimum three months of normal physiotherapy treatments where included. Eighteen of them (group 1) have received a leukocyte poor PRP injection (obtained using an aphaeresis machine (3)) and the other fifteen (group 2) two HA injections, all of them have benefited of standardized rehabilitation. Concerning the evaluation of the pathology, algofunctional tests (visual analogic scale (VAS), pressure algometer, IKDC score, VISAP score), isokinetic (associated to VAS) along with the patellar tendon ultrasonography (US) have been realized over three times (preinjection, after 6 weeks, after 3 months postinjections). RESULTS: The results of VAS (p<0,01), algometric scores (p<0,01), IKDC scores (p<0,01) and VISAP (p<0,01) show a considerable improvement in the two groups, but not for the US findings. For the group 1, isokinetic tests show significative results for the hamstrings in C60°/s with an improvement of maximum peak torque (p=0,01) for the pathological member, a diminution (p>0,05) for the healthy limb and during the analysis of the bilateral difference (p=0,0002). For the group 2, the improvement of quadriceps maximum peak torque in C240°/s is significant (p>0,01) for the pathological knee after 6 weeks post injections only. The VAS associated with isokinetic tests decreases significantly for all contraction modes after three months of study. CONCLUSIONS: Both PRP and HA can improve the symptoms of proximal patellar tendinopathy, even if the results are slightly better in the PRP group. REFERENCES: Andia I et al., Plateletrich plasma in the conservative treatment of painful tendinopathy: a systematic review and metaanalysis of controlled studies. Br Med Bull. 2014 Jun;110(1):99115. Kaux JF et al., Hyaluronic acid and tendon lesions. Muscles Ligaments Tendons J. 2016 Feb 13;5(4):2649. Kaux JF et al. Using platelet rich plasma to treat jumper's knees: Exploring the effect of a second closely timed infiltration. J Sci Med Sport. 2016 Mar;19(3):2004.
Disciplines :
Orthopedics, rehabilitation & sports medicine
Author, co-author :
Kaux, Jean-François  ;  Université de Liège - ULiège > Département des sciences de la motricité > Médecine physique, réadaptation et traumatologie du sport
Robertjot, Mathieu
SAMSON, Antoine ;  Centre Hospitalier Universitaire de Liège - CHU > Service de médecine de l'appareil locomoteur
Croisier, Jean-Louis ;  Université de Liège - ULiège > Département des sciences de la motricité > Kinésithérapie générale et réadaptation
Language :
English
Title :
Platelet-rich plasma versus hyaluronic acid to treat tendinopathies
Publication date :
September 2017
Event name :
10th EFSMA congress
Event organizer :
EFSMA
Event place :
Cascais, Portugal
Event date :
16-18 November 2017
Audience :
International
Journal title :
European Journal of Sports Medicine
eISSN :
1792-4979
Publisher :
European Federation of Sports Medicine Associations (EFSMA), Ankara, Greece
Special issue title :
Abstract book - 10th EFSMA congress
Volume :
5
Issue :
Supplement 1
Pages :
21-22
Peer reviewed :
Peer Reviewed verified by ORBi

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