Reference : Clinical and haematological alterations in foot and mouth disease virus naturally-inf...
Scientific congresses and symposiums : Poster
Life sciences : Veterinary medicine & animal health
Clinical and haematological alterations in foot and mouth disease virus naturally-infected domestic water buffaloes in Vietnam
Dam Van Phai, mailto [Université de Liège - ULiège > > > Doct. sc. vété. (paysage) >]
BUI TRAN ANH, Dao, mailto [Vietnam National University of Agriculture > Pathology > > Lecturer/ researcher >]
Desmecht, Daniel mailto [Université de Liège - ULiège > Département de morphologie et pathologie (DMP) > Pathologie spéciale et autopsies >]
University of Liege
[en] FMDV ; buffalo haematology ; water buffalo
[en] Foot and mouth disease (FMD) has been one of the most important epizootic diseases in several cloven-hoofed animals including buffaloes, causing severe economic losses in Vietnam. This study aimed at observing clinical indicators, physiological parameters, haematological and blood chemistry values of 30 buffaloes naturally infected with FMD virus (FMDV). The study was undertaken from January 2015 to February 2016 in Hanoi, Vietnam. Results show that buffaloes infected with FMDV displayed significantly higher fever, increased respiratory rate and increased heart frequency compared to healthy animals. Moreover, FMDV-infected animals always showed high fever and vesicular stomatitis, often showed edging nail congestive inflammation and, sometimes only, blisters on the nipple. Haematological indicators showed that FMDV-infected buffaloes were dehydrated (increased total protein). Besides, infected animals also underwent anaemia as mean corpuscular haemoglobin and mean corpuscular haemoglobin concentrations were plummeted. Total white blood cell count plummeted too, especially the number and proportion of neutrophils. Meanwhile, the number and proportion of lymphocytes sharply increased compared to healthy animals. Infected buffaloes also displayed signs of liver and heart damages as judged by an increase in concentration of AST and ALT, while there was not renal damage since creatinine concentration remained stable

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