Ion mobility; Mass spectrometry; TIMS; Drift tube; Traveling wave; Synthetic polymers; Poly(ethylene oxide)
Abstract :
[en] Over the years, polymer analyses using ion mobility-mass spectrometry (IM-MS) measurements have been performed on different ion mobility spectrometry (IMS) setups. In order to be able to compare literature data taken on different IM(-MS) instruments, ion heating and ion temperature evaluations have already been explored. Nevertheless, extrapolations to other analytes are difficult and thus straightforward same-sample instrument comparisons seem to be the only reliable way to make sure that the different IM(-MS) setups do not greatly change the gas phase behavior. We used a large range of degrees of polymerization (DP) of poly(ethylene oxide) PEO homopolymers to measure IMS drift times on three different IM-MS setups: a homemade drift tube (DT), a trapped (TIMS) and a travelling wave (T-Wave) IMS setup. The drift time evolutions were followed for increasing polymer DPs (masses) and charge states and they are found to be comparable and reproducible on the three instruments.
Disciplines :
Chemistry
Author, co-author :
Haler, Jean ; Université de Liège - ULiège > Département de chimie (sciences) > Laboratoire de spectrométrie de masse (L.S.M.)
Massonnet, Philippe ; Université de Liège - ULiège > Département de chimie (sciences) > Center for Analytical Research and Technology (CART)
Chirot, Fabien; Université de Lyon > Institut des Sciences Analytiques
Kune, Christopher ; Université de Liège - ULiège > Département de chimie (sciences) > Laboratoire de spectrométrie de masse (L.S.M.)
Comby-Zerbino, Clothilde; Université de Lyon > Institut Lumière Matière
Jordens, Jan; DSM > DSM Resolve
Honing, Maarten; DSM > DSM Resolve
Mengerink, Ynze; DSM > DSM Resolve
Far, Johann ; Université de Liège - ULiège > Département de chimie (sciences) > Center for Analytical Research and Technology (CART)
Dugourd, Philippe; Université de Lyon > Institut Lumière Matière
De Pauw, Edwin ; Université de Liège - ULiège > Département de chimie (sciences) > Laboratoire de spectrométrie de masse (L.S.M.)
Language :
English
Title :
Comparison of Different Ion Mobility Setups using Poly(ethylene oxide) PEO Polymers: Drift Tube, TIMS and T-Wave
Publication date :
2018
Journal title :
Journal of the American Society for Mass Spectrometry
ISSN :
1044-0305
eISSN :
1879-1123
Publisher :
Elsevier Science, New York, United States - New York
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