Reference : Mathematical modeling of extracorporeal CO2 removal therapy. A validation carried out...
Scientific journals : Article
Engineering, computing & technology : Multidisciplinary, general & others
http://hdl.handle.net/2268/214849
Mathematical modeling of extracorporeal CO2 removal therapy. A validation carried out on ten pigs
English
Habran, Simon mailto [Université de Liège > Département d'astrophys., géophysique et océanographie (AGO) > Thermodynamique des phénomènes irréversibles >]
Desaive, Thomas mailto [Université de Liège > Département d'astrophys., géophysique et océanographie (AGO) > Thermodynamique des phénomènes irréversibles >]
MORIMONT, Philippe mailto [Centre Hospitalier Universitaire de Liège - CHU > > Frais communs médecine - Pool assistants >]
LAMBERMONT, Bernard mailto [Centre Hospitalier Universitaire de Liège - CHU > > Frais communs médecine - Pool assistants >]
9-Mar-2018
Medical and Biological Engineering and Computing
Springer
56
3
421-434
Yes (verified by ORBi)
International
0140-0118
1741-0444
[en] Patient-specific modeling ; Critical care ; Extracorporeal lung support
[en] The extracorporeal CO2 removal device (ECCO2RD) is used in clinics to treat patients suffering from respiratory failures like acute respiratory distress syn- drome (ARDS) or chronic obstructive pulmonary disease (COPD). The aim of this device is to decarboxylate blood externally with low blood flow. A mathematical model is proposed to describe protective ventilation, ARDS, and an extracorporeal CO2 removal therapy (ECCO2RT). The sim- ulations are compared with experimental data carried out on ten pigs. The results show a good agreement between the mathematical simulations and the experimental data, which provides a nice validation of the model. This model is thus able to predict the decrease of PCO2 during ECCO2RT for different blood flows across the extracorporeal lung support.
Researchers ; Professionals
http://hdl.handle.net/2268/214849
10.1007/s11517-017-1694-y
https://doi.org/10.1007/s11517-017-1694-y

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