Reference : The use of platelet-rich plasma (PRP) to treat chronic tendinopathies: a technical an...
Scientific journals : Article
Human health sciences : Orthopedics, rehabilitation & sports medicine
Human health sciences : Laboratory medicine & medical technology
The use of platelet-rich plasma (PRP) to treat chronic tendinopathies: a technical analysis
Kaux, Jean-François mailto [Université de Liège > Département des sciences de la motricité > Médecine physique, réadaptation et traumatologie du sport >]
Emonds-Alt, Thibault [Centre Hospitalier Universitaire de Liège - CHU > > Service de médecine de l'appareil locomoteur >]
In press
Taylor & Francis
Yes (verified by ORBi)
United Kingdom
[en] Collection ; optimization ; platelet-rich plasma ; PRP ; standardization ; tendinopathies
[en] Platelet-rich plasma (PRP) is blood plasma with a high concentration of autologous platelets
which constitute an immense reservoir of growth factors. The clinical use of PRP is widespread
in various medical applications.
Although highly popular with athletes, the use of PRP for the treatment of tendinopathies
remains scientifically controversial, particularly due to the diversity of products that go by the
name of “PRP.” To optimize its use, it is important to look at the various stages of obtaining
In this literature review, we take a closer look at eight parameters which may influence the
quality of PRP: 1) anticoagulants used to preserve the best platelet function, 2) the speed of
centrifugation used to extract the platelets, 3) the platelet concentrations obtained, 4) the
impact of the concentration of red and while blood cells on PRP actions, 5) platelet activators
encouraging platelet degranulation and, hence, the release of growth factors, and 6) the use or
nonuse of local anesthetics when carrying out infiltration. In addition to these parameters, it
may be interesting to analyze other variables such as 7) the use of ultrasound guidance during
the injection with a view to determining the influence they have on potential recovery.

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