A comparison of pre and post-operative vedaprofen with ketoprofen for pain control in dogs.

Animals; Anti-Inflammatory Agents, Non-Steroidal/administration & dosage/therapeutic use; Dog Diseases/drug therapy; Dogs; Hydrocortisone/blood; Ketoprofen/administration & dosage/therapeutic use; Naphthalenes/administration & dosage/therapeutic use; Oral Surgical Procedures/adverse effects/veterinary; Pain, Postoperative/drug therapy/etiology/veterinary; Propionates/administration & dosage/therapeutic use

Abstract :

[en] BACKGROUND: This prospective randomized blinded clinical study aimed to investigate the potential of vedaprofen for preventive analgesia, comparing its analgesic effects with ketoprofen administered post-operatively in dogs undergoing maxillectomy or mandibulectomy. RESULTS: Pain control was effective and rescue analgesia was not necessary in any group. Pain scores were not significantly different between groups. The respiratory rate and rectal temperature were decreased in all groups at extubation until 6 hours post-extubation compared to baseline. Cortisol and epinephrine levels were increased only at 0.5 hours after extubation in all groups compared to baseline. CONCLUSIONS: Vedaprofen did not present any preventive analgesic effect. Pre- and postoperative vedaprofen were as effective as ketoprofen for postoperative pain control.

Disciplines :

Veterinary medicine & animal health

Author, co-author :

Fantoni, Denise Tabacchi

Ida, Keila ; Université de Liège > Dép. clinique des animaux de compagnie et des équidés (DCA) > Anesthésiologie et réanimation vétérinaires

de Almeida, Thais Ingles

Ambrosio, Aline Magalhaes

Language :

English

Title :

A comparison of pre and post-operative vedaprofen with ketoprofen for pain control in dogs.

Publication date :

2015

Journal title :

BMC Veterinary Research

eISSN :

1746-6148

Publisher :

BioMed Central, United Kingdom

Volume :

Pages :

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 19 July 2017

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