Reference : Serum albumin level and hospital mortality in acute non-ischemic heart failure.
Scientific journals : Article
Human health sciences : Cardiovascular & respiratory systems
Serum albumin level and hospital mortality in acute non-ischemic heart failure.
ANCION, Arnaud mailto [Centre Hospitalier Universitaire de Liège - CHU > > Service de cardiologie >]
Allepaerts, Sophie [> >]
Oury, Cécile mailto [Université de Liège > Département des sciences biomédicales et précliniques > GIGA-R : GIGA - Cardiovascular Sciences >]
Gori, Anne-Stephan [> >]
Pierard, Luc [Université de Liège > Département des sciences cliniques > Cardiologie - Pathologie spéciale et réhabilitation >]
Lancellotti, Patrizio mailto [Université de Liège > Département des sciences cliniques > Imagerie cardiaque fonctionnelle par échographie >]
ESC Heart Failure
Yes (verified by ORBi)
United Kingdom
[en] Albumin ; Heart failure ; Hospital mortality ; Outcome
[en] AIMS: Hypoalbuminemia is common in heart failure (HF), especially in elderly patients. It is associated with an increased risk of death. The present study sought to examine the prognostic significance of serum albumin level in the prediction of hospital mortality in patients admitted for acute non-ischemic HF. METHODS AND RESULTS: We examined the association between albumin and hospital mortality in a cohort of 546 patients admitted for acute non-ischemic HF. None of the patients had infectious disease, severe arrhythmias (atrial fibrillation, ventricular tachycardia, ventricular fibrillation), required invasive ventilation, or presented with acute coronary syndrome or primary valvular disease. Thirty-six patients (7%) died during the hospital stay. These patients were significantly older (78 +/- 9 vs. 72 +/- 12 years; P = 0.006), had higher heart rate (P < 0.0001), increased creatinine level (P = 0.01), lower systolic and diastolic blood pressures (P < 0.05), elevated leucocyte count (P = 0.001), and lower albumin levels (31.3 +/- 5.6 g/L vs. 36.9 +/- 4.1 g/L; P < 0.001). With multivariable analysis, age (P = 0.01), heart rate (P < 0.0003), diastolic blood pressure (P < 0.01), leukocyte count (P = 0.009), and serum albumin level (P < 0.0001) emerged as independent predictors of hospital mortality. Hypoalbuminemia (<34 g/L) yielded the best sensitivity (78.8%) and specificity (75%) for predicting hospital death. CONCLUSIONS: Serum albumin level measured at admission can serve as a simple prognostic factor in acute non-ischemic HF. Hypoalbuminemia is associated with increased risk of hospital mortality, especially in elderly patients.

File(s) associated to this reference

Fulltext file(s):

Restricted access
EHF2-4-138_ANCION.pdfPublisher postprint158.68 kBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.