Poster (Scientific congresses and symposiums)
Mass spectrometry imaging of small xenobiotics on Danio rerio : influence of molecular profiles modification as potential localization asset
Tiquet, Mathieu; Muller, Marc; De Pauw, Edwin
201765th ASMS Conference on Mass Spectrometry and Allied Topics
 

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Mass spectrometry imaging of small xenobiotics on Danio rerio influence of molecular profiles modification as potential localization asset.pdf
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Keywords :
Mass spectrometry imaging; zebrafish; metabolomics; MALDI; ROC curves
Abstract :
[en] MALDI Mass spectrometry often fail to locate small xenobiotics present in low concentration in tissues due to ion suppression effect. This new method compare tissues of contaminated zebrafish to controles with the statistical tool called receiver operating characteristic. Results cannot directly locate the xenobiotic but can indicate which tissues are affected by the contamination and thus give a hint on the biolocalization.
Research Center/Unit :
Laboratoire de spectrométrie de masse
Disciplines :
Chemistry
Author, co-author :
Tiquet, Mathieu ;  Université de Liège - ULiège > Form. doct. sc. (chimie - Bologne)
Other collaborator :
Muller, Marc  ;  Université de Liège > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire
De Pauw, Edwin  ;  Université de Liège > Département de chimie (sciences) > Laboratoire de spectrométrie de masse (L.S.M.)
Language :
English
Title :
Mass spectrometry imaging of small xenobiotics on Danio rerio : influence of molecular profiles modification as potential localization asset
Publication date :
02 June 2017
Number of pages :
112,35x55cm
Event name :
65th ASMS Conference on Mass Spectrometry and Allied Topics
Event organizer :
American Society for Mass Spectrometry
Event place :
Indianapolis, United States - Indiana
Event date :
3 juin au 8 juin 2017
Audience :
International
Funders :
FRIA - Fonds pour la Formation à la Recherche dans l'Industrie et dans l'Agriculture [BE]
Available on ORBi :
since 16 June 2017

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