A c-jun/splicing factors complex triggers altered pre-mRNA splcing in response to cisplatin

Deward, Adeline; Gabriel, Maude; Klinck, Roscoe; Chabot, Benoit; Figueroa, Maximiliano; Piette, Jacques; Colige, Alain; Lambert, Charles; Habraken, Yvette

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A c-jun/splicing factors complex triggers altered pre-mRNA splcing in response to cisplatin

Deward, Adeline; Gabriel, Maude; Klinck, Roscoe et al.

2016 • GIGA DAY Molecular Biology of Disease

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https://hdl.handle.net/2268/206935

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Keywords :

cisplatin; alternative splicing; c-Jun

Abstract :

[en] DNA lesions induce alternative splicing of hundreds of pre-messengers RNA. We established than c-Jun is required for this large scale reorganisation of the proteome after cisplatin treatment. .

Disciplines :

Biochemistry, biophysics & molecular biology

Author, co-author :

Deward, Adeline

Gabriel, Maude

Klinck, Roscoe

Chabot, Benoit

Figueroa, Maximiliano

Piette, Jacques

Colige, Alain

Lambert, Charles

Habraken, Yvette ; Université de Liège > GIGA-R : Virologie - Immunologie

Language :

English

Title :

A c-jun/splicing factors complex triggers altered pre-mRNA splcing in response to cisplatin

Publication date :

25 January 2016

Number of pages :

Event name :

GIGA DAY Molecular Biology of Disease

Event organizer :

GIGA URT Molecular Biology of diesease

Event date :

25/01 /2016

Name of the research project :

Alternative splicing induced by genotoxic antitumor agents

Available on ORBi :

since 06 February 2017

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