Canine cutaneous epitheliotropic T-cell lymphoma: a review

[en] Cutaneous epitheliotropic T-cell lymphoma in the dog is a rare neoplastic condition with unknown aetiology. The dermatitis is characterized by infi ltration of neoplastic T lymphocytes with a specifi c tropism for the epidermis and the adnexal structures. The different clinical and histological forms (mycosis fungoides, pagetoid reticulosis and Sézary syndrome) are reviewed. The disease in the dog resembles the human syndrome, but in 80% of the canine cases, neoplastic cells are CD4 − /CD8 + versus CD4 + /CD8 − in 90% of the human patients. Prognosis is poor with a survival time from few months to 2 years. Treatments frequently have a low effi cacy. New protocols using lomustine may improve the poor prognosis of the disease.

Disciplines :

Veterinary medicine & animal health

Author, co-author :

Fontaine, Jacques ; Université de Liège > Clinique vétérinaire universitaire (CVU)

Language :

English

Title :

Canine cutaneous epitheliotropic T-cell lymphoma: a review

Publication date :

2009

Journal title :

Veterinary and Comparative Oncology

ISSN :

1476-5810

Publisher :

Blackwell Publishing Ltd

Volume :

Vol. 7

Pages :

1-14

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 26 January 2017

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