Reference : Comparison of Various Indices of Energy Metabolism in Recumbent and Healthy Dairy Cows
Scientific journals : Article
Life sciences : Veterinary medicine & animal health
http://hdl.handle.net/2268/205720
Comparison of Various Indices of Energy Metabolism in Recumbent and Healthy Dairy Cows
English
[fr] Comparaison de différents indices du métabolisme énergétique chez des vaches couchées et des vaches saines
Guyot, Hugues mailto [Université de Liège > Département clinique des animaux de production (DCP) > Gestion de la santé des ruminants >]
Detilleux, Johann mailto [Université de Liège > Département des productions animales (DPA) > Génétique quantitative >]
Lebreton, Pascal []
Garnier, Catherine []
Bonvoisin, Marie []
Rollin, Frédéric mailto [Université de Liège > Département clinique des animaux de production (DCP) > Médecine interne des équidés, des ruminants et des porcs >]
Sandersen, Charlotte mailto [Université de Liège > Dép. clinique des animaux de compagnie et des équidés (DCA) > Anesthésiologie et réanimation vétérinaires >]
20-Jan-2017
PLoS ONE
Public Library of Science
12
1
1-11
Yes (verified by ORBi)
International
1932-6203
San Franscisco
CA
[en] RQUICKI ; Dairy Cattle ; Downer Cow Syndrome ; HOMA ; Lactation ; Metabolism
[en] BACKGROUND:

Downer cow syndrome (DCS) is often diagnosed in dairy cattle during the early post-partum period. The etiology of this condition is not completely understood, as it can be related to the energetic or electrolyte metabolism, as well as to infectious diseases or to trauma.

HYPOTHESIS/OBJECTIVES:

The aim of this study is to compare energy metabolism and insulin sensitivity indices and various biochemical parameters between recumbent and healthy dairy cows.

ANIMALS:

A prospective study has been undertaken on 361 recumbent and 80 healthy Holstein cows.

METHODS:

Plasmatic glucose, insulin, non-esterified fatty acid (NEFA) and β-hydroxybutyrate (BHB) were assayed in all cows in order to calculate the insulin sensitivity indices but also minerals (Calcium, Phosphorous and Magnesium), thyroxin and creatine kinase. Body Condition Scores (BCS) was assessed.

RESULTS:

Significant differences in NEFA, and the glucose and insulin sensitivity indices ("Homeostasis Model Assessment" HOMA, "Revised Quantitative Insulin Sensitivity Check Index" RQUICKI, RQUICKI-BHB) were observed between healthy and recumbent cows in the early post-parturient period indicating disturbances of glucose and insulin homeostasis in the recumbent cows. In the same manner, mineral concentrations were significantly different between healthy and recumbent cows. Glucose, insulin NEFA, and HOMA, were different between early post-partum downer cows and the DCS-affected cows later in lactation.

CONCLUSION AND CLINICAL IMPORTANCE:

Results indicate disturbances in energy homeostasis in DCS-affected dairy cows. Further research should determine a prognostic value of the indices in cows suffering from recumbency of metabolic origin
Fundamental and Applied Research for Animals and Health - FARAH
Researchers ; Professionals ; Students
http://hdl.handle.net/2268/205720
10.1371/journal.pone.0169716

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