Commentary :
In this issue of The Annals, Cho and colleagues [1] reported the association of thoracic aorta calcium score (TACS) to left ventricular (LV) hypertrophy and clinical outcomes in patients with severe aortic stenosis (AS). The main finding of the study was that high TACS was associated with LV hypertrophy, and it predicted less regression of LV mass and poor clinical outcomes following aortic valve replacement. This observation timely recalls that LV remodeling, a major determinant of outcome, is a complex pathophysiologic process.
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