Reference : Raman imaging for diagnostic application
Scientific congresses and symposiums : Poster
Physical, chemical, mathematical & earth Sciences : Chemistry
Raman imaging for diagnostic application
Malherbe, Cédric mailto [Université de Liège > Département de chimie (sciences) > Chimie analytique inorganique >]
Gilbert, Bernard mailto [Université de Liège > Département de chimie (sciences) > Département de chimie (sciences) >]
Eppe, Gauthier mailto [Université de Liège > Département de chimie (sciences) > Chimie analytique inorganique >]
Meeting of the Infrared and Raman Discussion Group (IRDG)
19 décembre 2016
[en] Specific dynamic biochemical compositions and molecular structures characterise healthy cells and tissues. This also stands for pathologies or cellular abnormalities which are accompanied by biochemical and molecular changes. Raman spectroscopy can provide unique inputs to correlate the molecular composition and its variations with the diagnosis. In addition, the presence of metal nanoparticles in the molecule vicinity induces a remarkable enhancement (up to 1000000 times) of the Raman signal of small molecules (known as SERS effect). It opens towards applications in the field of trace analysis. In preparation for clinical applications, we evaluate, by Raman mapping, the signal detected from a SERS target deposited on solid state support.

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