Reference : LE CAS CLINIQUE DU MOIS. Granulomatose sarcoidose-like chez les patients traites par ...
Scientific journals : Article
Human health sciences : Cardiovascular & respiratory systems
LE CAS CLINIQUE DU MOIS. Granulomatose sarcoidose-like chez les patients traites par anti-TNFalpha.
[en] Sarcoid-like granulomatosis in patients treated with anti-TNFalpha
Petrovici, Andreea [> >]
Kaiser, Marie [> >]
Louis, Renaud mailto [Université de Liège > Département des sciences cliniques > Pneumologie - Allergologie >]
NGUYEN DANG, Delphine mailto [Centre Hospitalier Universitaire de Liège - CHU > > Service de pneumologie - allergologie >]
Revue Médicale de Liège
Yes (verified by ORBi)
[en] Over recent years, anti-TNFalpha have been used to treat rheumatoid arthritis. The principal secondary effect of anti-TNFalpha is tuberculosis infections. Another paradoxical effect, previously less well understood, is the development of sarcoid-like granulomatous reactions. We report the case of a 36 year old woman who had been treated for 9 years with anti-TNF alpha. She developed a pulmonary sarcoid-like gra-nulomatosis, complication that is rare but not exceptional in patients treated with TNF-blockers. Discontinuation of anti TNF usually led to recovery. It has been suggested that these reactions mainly occur with etanercept, but this requires further confirmation.

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