Extending abdominal aortic aneurysm detection to older age groups: preliminary results from the Liege screening programme.

MAKRYGIANNIS, Georgios; Labalue, Philippe; Erpicum, Marie; Schlitz, Martin; SEIDEL, Laurence; El Hachemi, Mounia; GANGOLF, Marjorie; Albert, Adelin; Defraigne, Jean-Olivier; Lindholt, Jes S.; Sakalihasan, Natzi

doi:10.1016/j.avsg.2016.02.034

Article (Scientific journals)

Extending abdominal aortic aneurysm detection to older age groups: preliminary results from the Liege screening programme.

MAKRYGIANNIS, Georgios; Labalue, Philippe; Erpicum, Marie et al.

2016 • In Annals of Vascular Surgery

Peer Reviewed verified by ORBi

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https://hdl.handle.net/2268/201394

DOI
10.1016/j.avsg.2016.02.034

PubMed
27364735

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Keywords :

abdominal aortic aneurysm; epidemiology; prevalence; screening policies; ultrasonography; varicose veins

Abstract :

[en] BACKGROUND: There is evident benefit in terms of reduced aneurysm related mortality from screening programmes of abdominal aortic aneurysm (AAA) in men aged 65 and more. Recent studies in UK and Sweden have shown a decline of the prevalence of AAA in the general population. Current screening policies (e.g. men aged 65-74 years) however do not account for ageing and increased life expectancy of western populations. This study investigated AAA detection by extending the target population to older age groups (75-85 years). METHODS: AAA screening was conducted in the County of Chaudfontaine (Liege, Belgium) on the population of elderly (N=3,054). The participation rate was 36%. The 1,101 participants (722 men aged 65-85 and 379 women aged 74-85 years) were examined by ultrasound (US) scan. AAA was defined as an infrarenal aortic outer-outer diameter of at least 3 cm. Demographics, clinical parameters and risk factors were also recorded. AAA prevalence was estimated and patients with and without AAA were compared by logistic regression. RESULTS: The overall AAA prevalence was 3.6% (n=40). In female participants, AAA prevalence was low (1.3%). In men, it amounted 2.7% in the 65-74 age group but rose to 7.3% in the age-extended group (75-85 years). Further in addition to age, height, current smoking, history of coronary artery disease, hypercholesterolemia, peripheral artery disease of the lower limbs and varicose veins were significantly associated with the presence of AAA. CONCLUSION: These preliminary findings, based on a representative sample of the elderly population of the Liege region, support the idea that current AAA screening policies should be updated to cover an increasingly ageing population. The presence of varicose veins as a potential risk factor for AAA should also be considered during screening.

Disciplines :

Genetics & genetic processes
Surgery

Author, co-author :

MAKRYGIANNIS, Georgios ; Centre Hospitalier Universitaire de Liège - CHU > Chirurgie abdo, sénologique, endocrine et de transplantation

Labalue, Philippe

Erpicum, Marie ; Université de Liège > Département des sciences de la santé publique > Département des sciences de la santé publique

Schlitz, Martin

SEIDEL, Laurence ; Centre Hospitalier Universitaire de Liège - CHU > Service des informations médico économiques (SIME)

El Hachemi, Mounia

GANGOLF, Marjorie ; Centre Hospitalier Universitaire de Liège - CHU > Service des informations médico économiques (SIME)

Albert, Adelin ; Université de Liège > Département des sciences de la santé publique > Département des sciences de la santé publique

Defraigne, Jean-Olivier ; Université de Liège > Département des sciences cliniques > Chirurgie cardio-vasculaire et thoracique

Lindholt, Jes S.

Sakalihasan, Natzi ; Université de Liège > Département des sciences cliniques > Biologie pathologique des parois artérielles

Language :

English

Title :

Extending abdominal aortic aneurysm detection to older age groups: preliminary results from the Liege screening programme.

Publication date :

2016

Journal title :

Annals of Vascular Surgery

ISSN :

0890-5096

eISSN :

1615-5947

Publisher :

Springer Verlag, New York, United States - New York

Peer reviewed :

Peer Reviewed verified by ORBi

Commentary :

Available on ORBi :

since 02 September 2016

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