Poster (Scientific congresses and symposiums)
Individual variation of gait parameters along a 500 meter walk in people with multiple sclerosis and healthy volonteers
Phan-Ba, Rémy; Giet, Amaury; Pierard, Sébastien et al.
201520th Annual Conference of Rehabilitaon In Multiple Sclerosis (RIMS)
 

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Keywords :
Gait analysis; Multiple sclerosis; Neurorehabilitation; GAIMS
Abstract :
[en] Background: we previously demonstrated the usefulness of the Deceleration Index (DI, the ratio between the last 100m of the Timed 500-Meter Walk test –T500MW – and the walking speed - WS – of the Timed 25-Foot Walk Test with a propelled start – T25FW+) to evaluate motor fatigue over a long walking distance in people with multiple sclerosis (pwMS). We also recently designed and internally validated a new gait analysis tool for pwMS (GAIMS) that can measure other relevant gait characteristics than the sole WS, such as ataxia, asymmetry and perhaps spasticity. Aims: (i) To compare various gait characteristics between the last and the first 100m of the T500MW in a population of pwMS and healthy volunteers (HV), (ii) to compare the ratio between the last and the first 100m of the T500MW with the DI, and (iii) their relationship with the EDSS. Methods : Subjects were asked to perform the T25FW+ and the T500MW as part of a multimodal evaluation at the MS Clinic of the CHU of Liège. Their gait characteristics were measured using GAIMS. (i) Paired Student’s t-tests were performed on various gait characteristics extracted during the last and first 100m of the T500MW with .05 as a level of significance, (ii) Spearman correlation coefficient (ρ) was calculated (ii) between these ratio and (iii) subject’s EDSS. Results: Seventy-one pwMS and 129 were enrolled in our study. (i) Significant differences were observed for speed related gait characteristics between the last and first 100m of the T500MW, but also for gait characteristics related to ataxia and precision of foot placement. (ii) A moderate positive correlation was observed between the WS ratio of the last and first 100m of the T500MW and the DI. (iii) The correlation between the DI and the EDSS was weakly negative, while the one between the last and first 100m of the T500MW ratio and the EDSS was moderatly negative. Conclusion: (i) As previously demonstrated, we here confirm that alongside to WS, there are other gait features affected by locomotor fatigue over a long walking distance, (ii) the moderate positive correlation between the DI and the last/first 100m of the T500MW indicates that these measures are not the same and that next to a long distance walking test such as the T500MW, a short one such as the T25FW+ remains useful. (iii) The last/first 100m of the T500MW is better correlated to the EDSS and might be a better predictive tool of pwMS’ neurologic state than the DI.
Research center :
Telim; Montefiore
Disciplines :
Neurology
Author, co-author :
Phan-Ba, Rémy 
Giet, Amaury
Pierard, Sébastien ;  Université de Liège > Dép. d'électric., électron. et informat. (Inst.Montefiore) > Télécommunications
Van Droogenbroeck, Marc  ;  Université de Liège > Dép. d'électric., électron. et informat. (Inst.Montefiore) > Télécommunications
Language :
English
Title :
Individual variation of gait parameters along a 500 meter walk in people with multiple sclerosis and healthy volonteers
Alternative titles :
[fr] Variation individuelle des paramètres de marche au long d'une distance de 500m chez des personnes atteintes de sclérose en plaques et chez des volontaires sains
Publication date :
10 April 2015
Event name :
20th Annual Conference of Rehabilitaon In Multiple Sclerosis (RIMS)
Event organizer :
RIMS
Event place :
Milan, Italy
Event date :
from 09-04-2015 to 11-04-2015
Audience :
International
Available on ORBi :
since 05 August 2016

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