Article (Scientific journals)
Revised diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a new classification from the European Society for Blood and Marrow Transplantation
Mohty, M.; Malard, F.; Abecassis, M. et al.
2016In Bone Marrow Transplantation, 51, p. 906-912
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Abstract :
[en] Sinusoidal obstruction syndrome, also known as veno-occlusive disease (SOS/VOD), is a potentially life threatening complication that can develop after hematopoietic cell transplantation. Although SOS/VOD progressively resolves within a few weeks in most patients, the most severe forms result in multi-organ dysfunction and are associated with a high mortality rate (480%). Therefore, careful attention must be paid to allow an early detection of SOS/VOD, particularly as drugs have now proven to be effective and licensed for its treatment. Unfortunately, current criteria lack sensitivity and specificity, making early identification and severity assessment of SOS/VOD difficult. The aim of this work is to propose a new definition for diagnosis, and a severity-grading system for SOS/VOD in adult patients, on behalf of the European Society for Blood and Marrow Transplantation.
Disciplines :
Hematology
Author, co-author :
Mohty, M.
Malard, F.
Abecassis, M.
Aerts, E.
Alaskar, AS.
Aljurf, M.
Bader, P
Baron, Frédéric  ;  Université de Liège > GIGA-R : Hématologie
Bazarbachi, A.
Blaise, D.
Ciceri, F.
Corbacioglu, S.
Dalle, JH.
Dignan, F.
Fukuda, T.
Huynh, A.
Masszi, T.
Michallet, M.
Nagler, A.
NiChoghaile, M.
Okamoto, S.
Pagliuca, A.
Peters, C.
Petersen, FB.
Richardson, PG.
Ruutu, T.
Savani, BN.
Wallhult, E.
Yakoub-Agha, I.
Duarte, RF.
Carreras, E.
More authors (21 more) Less
Language :
English
Title :
Revised diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a new classification from the European Society for Blood and Marrow Transplantation
Publication date :
2016
Journal title :
Bone Marrow Transplantation
ISSN :
0268-3369
eISSN :
1476-5365
Publisher :
Nature Publishing Group, London, United Kingdom
Volume :
51
Pages :
906-912
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
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