U. Brandt Energy converting NADH:quinone oxidoreductase (complex I) Annu. Rev. Biochem. 75 2006 69 92
J. Hirst Mitochondrial complex I Annu. Rev. Biochem. 82 2013 551 575
S. Kerscher, S. Dröse, V. Zickermann, and U. Brandt The three families of respiratory NADH dehydrogenases G. Schäfer, H. Penefsky, Bioenergetics 2008 Springer Berlin Heidelberg 185 222
A.M.P. Melo, T.M. Bandeiras, and M. Teixeira New insights into type II NAD(P)H:quinone oxidoreductases Microbiol. Mol. Biol. Rev. 68 2004 603 616
B. Barquera The sodium pumping NADH:quinone oxidoreductase (Na+-NQR), a unique redox-driven ion pump J. Bioenerg. Biomembr. 46 2014 289 298
B. Barquera, W. Zhou, J.E. Morgan, and R.B. Gennis Riboflavin is a component of the Na+-pumping NADH-quinone oxidoreductase from Vibrio cholerae PNAS 99 2002 10322 10324
J.A. Letts, and L.A. Sazanov Gaining mass: the structure of respiratory complex I - from bacterial towards mitochondrial versions Curr. Opin. Struct. Biol. 33 2015 135 145
L.A. Sazanov, and P. Hinchliffe Structure of the hydrophilic domain of respiratory complex I from Thermus thermophilus Science 311 2006 1430 1436
T. Friedrich, and D. Scheide The respiratory complex I of bacteria, archaea and eukarya and its module common with membrane-bound multisubunit hydrogenases FEBS Lett. 479 2000 1 5
M.A. Spero, F.O. Aylward, C.R. Currie, and T.J. Donohue Phylogenomic analysis and predicted physiological role of the proton-translocating NADH:quinone oxidoreductase (Complex I) across bacteria mBio 6 2015
R.G. Efremov, R. Baradaran, and L.A. Sazanov The architecture of respiratory complex I Nature 465 2010 441 445
C.-y. Yip, M.E. Harbour, K. Jayawardena, I.M. Fearnley, and L.A. Sazanov Evolution of respiratory complex I: "supernumerary" subunits are present in the α-proteobacterial enzyme J. Biol. Chem. 286 2011 5023 5033
K. Kmita, and V. Zickermann Accessory subunits of mitochondrial complex I Biochem. Soc. Trans. 41 2013 1272 1279
J. Hirst Why does mitochondrial complex I have so many subunits? Biochem. J. 437 2011 e1 e3
P. Cardol Mitochondrial NADH:ubiquinone oxidoreductase (complex I) in eukaryotes: a highly conserved subunit composition highlighted by mining of protein databases Biochim. Biophys. Acta 1807 2011 1390 1397
N. Grigorieff Three-dimensional structure of bovine NADH:ubiquinone oxidoreductase (complex I) at 22A in ice J. Mol. Biol. 277 1998 1033 1046
V. Guenebaut, R. Vincentelli, D. Mills, H. Weiss, and K.R. Leonard Three-dimensional structure of NADH-dehydrogenase from Neurospora crassa by electron microscopy and conical tilt reconstruction J. Mol. Biol. 265 1997 409 418
K. Leonard, H. Haiker, and H. Weiss Three-dimensional structure of NADH: ubiquinone reductase (complex I) from Neurospora mitochondria determined by electron microscopy of membrane crystals J. Mol. Biol. 194 1987 277 286
M. Mimaki, X. Wang, M. McKenzie, D.R. Thorburn, and M.T. Ryan Understanding mitochondrial complex I assembly in health and disease Biochim. Biophys. Acta 1817 2012 851 862
R. Baradaran, J.M. Berrisford, G.S. Minhas, and L.A. Sazanov Crystal structure of the entire respiratory complex I Nature 494 2013 443 448
V. Zickermann, C. Wirth, H. Nasiri, K. Siegmund, H. Schwalbe, C. Hunte, and U. Brandt Structural biology. Mechanistic insight from the crystal structure of mitochondrial complex I Science 347 2015 44 49
J. Zhu, M.S. King, M. Yu, L. Klipcan, A.G.W. Leslie, and J. Hirst Structure of subcomplex Iβ of mammalian respiratory complex I leads to new supernumerary subunit assignments PNAS 112 2015 12087 12092
K.R. Vinothkumar, J. Zhu, and J. Hirst Architecture of mammalian respiratory complex I Nature 515 2014 80 84
S. Shimada, K. Shinzawa-Itoh, S. Amano, Y. Akira, A. Miyazawa, T. Tsukihara, K. Tani, C. Gerle, and S. Yoshikawa Three-dimensional structure of bovine heart NADH: ubiquinone oxidoreductase (complex I) by electron microscopy of a single negatively stained two-dimensional crystal Microscopy (Oxf) 63 2014 167 174
C. Hunte, V. Zickermann, and U. Brandt Functional modules and structural basis of conformational coupling in mitochondrial complex I Science 329 2010 448 451
R.G. Efremov, and L.A. Sazanov Structure of the membrane domain of respiratory complex I Nature 476 2011 414 420
T. Ohnishi Structural biology: piston drives a proton pump Nature 465 2010 428 429
S. Zhu, and S.B. Vik Constraining the lateral helix of respiratory complex I by cross-linking does not impair enzyme activity or proton translocation J. Biol. Chem. 290 2015 20761 20773
S. Steimle, C. Schnick, E.-M. Burger, F. Nuber, D. Krämer, H. Dawitz, S. Brander, B. Matlosz, J. Schäfer, K. Maurer, U. Glessner, and T. Friedrich Cysteine scanning reveals minor local rearrangements of the horizontal helix of respiratory complex I Mol. Microbiol. 98 2015 151 161
T. Gabaldón, D. Rainey, and M.A. Huynen Tracing the evolution of a large protein complex in the Eukaryotes, NADH:ubiquinone oxidoreductase (Complex I) J. Mol. Biol. 348 2005 857 870
J.J.V. Hellemond, A.V.D. Klei, S.H.V. Weelden, and A.G.M. Tielens Biochemical and evolutionary aspects of anaerobically functioning mitochondria Philos. Trans. R. Soc. Lond. B. Biol. Sci. 358 2003 205 215
C.W. Stairs, M.M. Leger, and A.J. Roger Diversity and origins of anaerobic metabolism in mitochondria and related organelles Philos Trans. R. Soc Lond B Biol Sci. 370 2015
A. Stechmann, K. Hamblin, V. Perez-Brocal, D. Gaston, G.S. Richmond, M. van der Giezen, C.G. Clark, and A.J. Roger Organelles in Blastocystis that blur the distinction between mitochondria and hydrogenosomes Curr. Biol. 18 2008 580 585
B. Boxma, R.M. de Graaf, G.W. van der Staay, T.A. van Alen, G. Ricard, T. Gabaldon, A.H. van Hoek, S.Y. Moon-van der Staay, W.J. Koopman, J.J. van Hellemond, A.G. Tielens, T. Friedrich, M. Veenhuis, M.A. Huynen, and J.H. Hackstein An anaerobic mitochondrion that produces hydrogen Nature 434 2005 74 79
M. Marcet-Houben, G. Marceddu, and T. Gabaldon Phylogenomics of the oxidative phosphorylation in fungi reveals extensive gene duplication followed by functional divergence BMC Evol. Biol. 9 2009 295
T.Y. James, A. Pelin, L. Bonen, S. Ahrendt, D. Sain, N. Corradi, and J.E. Stajich Shared signatures of parasitism and phylogenomics unite Cryptomycota and Microsporidia Curr. Biol. 23 2013 1548 1553
P. Flegontov, J. Michálek, J. Janouškovec, D.-H. Lai, M. Jirků, E. Hajdušková, A. Tomčala, T.D. Otto, P.J. Keeling, A. Pain, M. Oborník, and J. Lukeš Divergent mitochondrial respiratory chains in phototrophic relatives of Apicomplexan parasites Mol. Biol. Evol. 32 2015 1115 1131
E.A. Nash, R.E.R. Nisbet, A.C. Barbrook, and C.J. Howe Dinoflagellates: a mitochondrial genome all at sea Trends Genet. 24 2008 328 335
A.G. Rasmusson, D.A. Geisler, and I.M. Møller The multiplicity of dehydrogenases in the electron transport chain of plant mitochondria Mitochondrion 8 2008 47 60
E. Skippington, T.J. Barkman, D.W. Rice, and J.D. Palmer Miniaturized mitogenome of the parasitic plant Viscum scurruloideum is extremely divergent and dynamic and has lost all nad genes PNAS 112 2015 E3515 E3524
G. Petersen, A. Cuenca, I.M. Møller, and O. Seberg Massive gene loss in mistletoe (Viscum, Viscaceae) mitochondria Sci. Rep. 5 2015 17588
M.G. Matus-Ortega, K.G. Salmerón-Santiago, O. Flores-Herrera, G. Guerra-Sánchez, F. Martínez, J.L. Rendón, and J.P. Pardo The alternative NADH dehydrogenase is present in mitochondria of some animal taxa Comp. Biochem. Physiol. Part D Genomics Proteomics 6 2011 256 263
H.P. Braun, S. Binder, A. Brennicke, H. Eubel, A.R. Fernie, I. Finkemeier, J. Klodmann, A.C. Konig, K. Kuhn, E. Meyer, T. Obata, M. Schwarzlander, M. Takenaka, and A. Zehrmann The life of plant mitochondrial complex I Mitochondrion 19 2014 295 313 Pt B
K.J. Newton, S. Gabay-Laughnan, and R. De Paepe Mitochondrial mutations in plants D. Day, A.H. Millar, J. Whelan, Plant Mitochondria: From Genome to Function 2004 Springer Netherlands 121 141
T. Salinas, V. Larosa, P. Cardol, L. Marechal-Drouard, and C. Remacle Respiratory-deficient mutants of the unicellular green alga Chlamydomonas: a review Biochimie 100 2014 207 218
N.V. Dudkina, H. Eubel, W. Keegstra, E.J. Boekema, and H.P. Braun Structure of a mitochondrial supercomplex formed by respiratory-chain complexes I and III Proc. Natl. Acad. Sci. U. S. A. 102 2005 3225 3229
J. Klodmann, S. Sunderhaus, M. Nimtz, L. Jansch, and H.P. Braun Internal architecture of mitochondrial complex I from Arabidopsis thaliana Plant Cell 22 2010 797 810
P. Hinchliffe, and L.A. Sazanov Organization of iron-sulfur clusters in respiratory complex I Science 309 2005 771 774
M.L. Verkhovskaya, N. Belevich, L. Euro, M. Wikstrom, and M.I. Verkhovsky Real-time electron transfer in respiratory complex I Proc. Natl. Acad. Sci. U. S. A. 105 2008 3763 3767
J.L. Heazlewood, K.A. Howell, and A.H. Millar Mitochondrial complex I from Arabidopsis and rice: orthologs of mammalian and fungal components coupled with plant-specific subunits Biochim. Biophys. Acta 1604 2003 159 169
E.H. Meyer, C. Solheim, S.K. Tanz, G. Bonnard, and A.H. Millar Insights into the composition and assembly of the membrane arm of plant complex I through analysis of subcomplexes in Arabidopsis mutant lines J. Biol. Chem. 286 2011 26081 26092
P. Cardol, F. Vanrobaeys, B. Devreese, J. Van Beeumen, R.F. Matagne, and C. Remacle Higher plant-like subunit composition of mitochondrial complex I from Chlamydomonas reinhardtii: 31 conserved components among eukaryotes Biochim. Biophys. Acta (BBA) - Bioenergetics 1658 2004 212 224
K. Peters, K. Belt, and H.P. Braun 3D gel map of Arabidopsis Complex I Front. Plant Sci. 4 2013 153
J. Hirst, J. Carroll, I.M. Fearnley, R.J. Shannon, and J.E. Walker The nuclear encoded subunits of complex I from bovine heart mitochondria Biochim. Biophys. Acta 1604 2003 135 150
J. Carroll, I.M. Fearnley, J.M. Skehel, R.J. Shannon, J. Hirst, and J.E. Walker Bovine complex I is a complex of 45 different subunits J. Biol. Chem. 281 2006 32724 32727
V. Knoop, W. Schuster, B. Wissinger, and A. Brennicke Trans splicing integrates an exon of 22 nucleotides into the nad5 mRNA in higher plant mitochondria EMBO J. 10 1991 3483 3493
B. Lippok, A. Brennicke, and M. Unseld The rps4-gene is encoded upstream of the nad2-gene in Arabidopsis mitochondria Biol. Chem. Hoppe Seyler 377 1996 251 257
A.F. de Longevialle, E.H. Meyer, C. Andres, N.L. Taylor, C. Lurin, A.H. Millar, and I.D. Small The pentatricopeptide repeat gene OTP43 is required for trans-splicing of the mitochondrial nad1 Intron 1 in Arabidopsis thaliana Plant Cell 19 2007 3256 3265
C. Remacle, P. Hamel, V. Larosa, and N. Subrahmanian Complexes I in the Green Lineage first ed. 2012 Springer New York
P. Cardol, L. Boutaffala, S. Memmi, B. Devreese, R.F. Matagne, and C. Remacle In Chlamydomonas, the loss of ND5 subunit prevents the assembly of whole mitochondrial complex I and leads to the formation of a low abundant 700 kDa subcomplex Biochim. Biophys. Acta 1777 2008 388 396
E.H. Meyer, N.L. Taylor, and A.H. Millar Resolving and identifying protein components of plant mitochondrial respiratory complexes using three dimensions of gel electrophoresis J. Proteome Res. 7 2008 786 794
J. Klodmann, and H.P. Braun Proteomic approach to characterize mitochondrial complex I from plants Phytochemistry 72 2011 1071 1080
Y. Wang, C. Carrie, E. Giraud, D. Elhafez, R. Narsai, O. Duncan, J. Whelan, and M.W. Murcha Dual location of the mitochondrial preprotein transporters B14.7 and Tim23-2 in complex I and the TIM17:23 complex in Arabidopsis links mitochondrial activity and biogenesis Plant Cell 24 2012 2675 2695
J. Carroll, I.M. Fearnley, R.J. Shannon, J. Hirst, and J.E. Walker Analysis of the subunit composition of complex I from bovine heart mitochondria Mol. Cell. Proteomics 2 2003 117 126
S. Drose, S. Krack, L. Sokolova, K. Zwicker, H.D. Barth, N. Morgner, H. Heide, M. Steger, E. Nubel, V. Zickermann, S. Kerscher, B. Brutschy, M. Radermacher, and U. Brandt Functional dissection of the proton pumping modules of mitochondrial complex I PLoS Biol. 9 2011 e1001128
J. Zhu, M.S. King, M. Yu, L. Klipcan, A.G. Leslie, and J. Hirst Structure of subcomplex Ibeta of mammalian respiratory complex I leads to new supernumerary subunit assignments Proc. Natl. Acad. Sci. U. S. A. 112 2015 12087 12092
M. Lazarou, D.R. Thorburn, M.T. Ryan, and M. McKenzie Assembly of mitochondrial complex I and defects in disease Biochim. Biophys. Acta 1793 2009 78 88
H. Angerer, K. Zwicker, Z. Wumaier, L. Sokolova, H. Heide, M. Steger, S. Kaiser, E. Nubel, B. Brutschy, M. Radermacher, U. Brandt, and V. Zickermann A scaffold of accessory subunits links the peripheral arm and the distal proton-pumping module of mitochondrial complex I Biochem. J. 437 2011 279 288
R. Szklarczyk, B.F. Wanschers, S.B. Nabuurs, J. Nouws, L.G. Nijtmans, and M.A. Huynen NDUFB7 and NDUFA8 are located at the intermembrane surface of complex I FEBS Lett. 585 2011 737 743
J.M. Berrisford, and L.A. Sazanov Structural basis for the mechanism of respiratory complex I J. Biol. Chem. 284 2009 29773 29783
K. Kuhn, T. Obata, K. Feher, R. Bock, A.R. Fernie, and E.H. Meyer Complete Mitochondrial Complex I Deficiency Induces an Upregulation of Respiratory Fluxes That is Abolished by Traces of Functional Complex I Plant Physiol 2015
E.H. Meyer Proteomic investigations of complex I composition: how to define a subunit? Front. Plant Sci. 3 2012 106
Q. Wang, R. Fristedt, X. Yu, Z. Chen, H. Liu, Y. Lee, H. Guo, S.S. Merchant, and C. Lin The gamma-carbonic anhydrase subcomplex of mitochondrial complex I is essential for development and important for photomorphogenesis of Arabidopsis Plant Physiol. 160 2012 1373 1383
M. Perales, H. Eubel, J. Heinemeyer, A. Colaneri, E. Zabaleta, and H.-P. Braun Disruption of a nuclear gene encoding a mitochondrial gamma carbonic anhydrase reduces complex I and supercomplex I + III2 levels and alters mitochondrial physiology in Arabidopsis J. Mol. Biol. 350 2005 263 277
S. Sunderhaus, N.V. Dudkina, L. Jansch, J. Klodmann, J. Heinemeyer, M. Perales, E. Zabaleta, E.J. Boekema, and H.P. Braun Carbonic anhydrase subunits form a matrix-exposed domain attached to the membrane arm of mitochondrial complex I in plants J. Biol. Chem. 281 2006 6482 6488
D. Soto, J.P. Cordoba, F. Villarreal, C. Bartoli, J. Schmitz, V.G. Maurino, H.P. Braun, G.C. Pagnussat, and E. Zabaleta Functional Characterization of Mutants Affected in the Carbonic Anhydrase Domain of the Respiratory Complex I in Arabidopsis thaliana Plant J 2015
S. Fromm, J. Going, C. Lorenz, C. Peterhansel, and H.P. Braun Depletion of the "gamma-type carbonic anhydrase-like" subunits of complex I affects central mitochondrial metabolism in Arabidopsis thaliana Biochim. Biophys. Acta 1857 2015 60 71
S. Massoz, V. Larosa, C. Plancke, M. Lapaille, B. Bailleul, D. Pirotte, M. Radoux, P. Leprince, N. Coosemans, R.F. Matagne, C. Remacle, and P. Cardol Inactivation of genes coding for mitochondrial Nd7 and Nd9 complex I subunits in Chlamydomonas reinhardtii. Impact of complex I loss on respiration and energetic metabolism Mitochondrion 19 2014 365 374 Pt B
S. Massoz, V. Larosa, B. Horrion, R.F. Matagne, C. Remacle, and P. Cardol Isolation of Chlamydomonas reinhardtii mutants with altered mitochondrial respiration by chlorophyll fluorescence measurement J. Biotechnol. 2015
C. Remacle, D. Baurain, P. Cardol, and R.F. Matagne Mutants of Chlamydomonas reinhardtii deficient in mitochondrial complex I: characterization of two mutations affecting the nd1 coding sequence Genetics 158 2001 1051 1060
P. Cardol, M. Lapaille, P. Minet, F. Franck, R.F. Matagne, and C. Remacle ND3 and ND4L subunits of mitochondrial complex I, both nucleus encoded in Chlamydomonas reinhardtii, are required for activity and assembly of the enzyme Eukaryot. Cell 5 2006 1460 1467
C. Remacle, P. Cardol, N. Coosemans, M. Gaisne, and N. Bonnefoy High-efficiency biolistic transformation of Chlamydomonas mitochondria can be used to insert mutations in complex I genes Proc. Natl. Acad. Sci. U. S. A. 103 2006 4771 4776
V. Larosa, N. Coosemans, P. Motte, N. Bonnefoy, and C. Remacle Reconstruction of a human mitochondrial complex I mutation in the unicellular green alga Chlamydomonas Plant J. 70 2012 759 768
P. Cardol, R.F. Matagne, and C. Remacle Impact of mutations affecting ND mitochondria-encoded subunits on the activity and assembly of complex I in Chlamydomonas. Implication for the structural organization of the enzyme J. Mol. Biol. 319 2002 1211 1221
M.R. Barbieri, V. Larosa, C. Nouet, N. Subrahmanian, C. Remacle, and P.P. Hamel A forward genetic screen identifies mutants deficient for mitochondrial complex I assembly in Chlamydomonas reinhardtii Genetics 188 2011 349 358
E.H. Meyer, T. Tomaz, A.J. Carroll, G. Estavillo, E. Delannoy, S.K. Tanz, I.D. Small, B.J. Pogson, and A.H. Millar Remodeled respiration in ndufs4 with low phosphorylation efficiency suppresses Arabidopsis germination and growth and alters control of metabolism at night Plant Physiol. 151 2009 603 619
V. Zickermann, S. Kerscher, K. Zwicker, M.A. Tocilescu, M. Radermacher, and U. Brandt Architecture of complex I and its implications for electron transfer and proton pumping Biochim. Biophys. Acta 1787 2009 574 583
N.N. Rudenko, L.K. Ignatova, T.P. Fedorchuk, and B.N. Ivanov Carbonic anhydrases in photosynthetic cells of higher plants Biochemistry (Mosc) 80 2015 674 687
K. Peters, N.V. Dudkina, L. Jansch, H.P. Braun, and E.J. Boekema A structural investigation of complex I and I + III2 supercomplex from Zea mays at 11-13A resolution: assignment of the carbonic anhydrase domain and evidence for structural heterogeneity within complex I Biochim. Biophys. Acta 1777 2008 84 93
J.B. Bultema, H.P. Braun, E.J. Boekema, and R. Kouril Megacomplex organization of the oxidative phosphorylation system by structural analysis of respiratory supercomplexes from potato Biochim. Biophys. Acta 1787 2009 60 67
B.E. Alber, and J.G. Ferry A carbonic anhydrase from the archaeon Methanosarcina thermophila Proc. Natl. Acad. Sci. U. S. A. 91 1994 6909 6913
R.M. Gawryluk, and M.W. Gray Evidence for an early evolutionary emergence of gamma-type carbonic anhydrases as components of mitochondrial respiratory complex I BMC Evol. Biol. 10 2010 176
B. Combettes, and J.M. Grienenberger Analysis of wheat mitochondrial complex I purified by a one-step immunoaffinity chromatography Biochimie 81 1999 645 653
U. Herz, W. Schroder, A. Liddell, C.J. Leaver, A. Brennicke, and L. Grohmann Purification of the NADH:ubiquinone oxidoreductase (complex I) of the respiratory chain from the inner mitochondrial membrane of Solanum tuberosum J. Biol. Chem. 269 1994 2263 2269
S. Leterme, and M. Boutry Purification and preliminary characterization of mitochondrial complex I (NADH: ubiquinone reductase) from broad bean (Vicia faba L.) Plant Physiol. 102 1993 435 443
J. Klodmann, D. Lewejohann, and H.P. Braun Low-SDS blue native PAGE Proteomics 11 2011 1834 1839
A.G. Rasmusson, V. Heiser, E. Zabaleta, A. Brennicke, and L. Grohmann Physiological, biochemical and molecular aspects of mitochondrial complex I in plants Biochim. Byophys. Acta 1364 1998 101 111
E.H. Meyer, J.L. Heazlewood, and A.H. Millar Mitochondrial acyl carrier proteins in Arabidopsis thaliana are predominantly soluble matrix proteins and none can be confirmed as subunits of respiratory Complex I Plant Mol. Biol. 64 2007 319 327
M.J. Runswick, I.M. Fearnley, J.M. Skehel, and J.E. Walker Presence of an acyl carrier protein in NADH:ubiquinone oxidoreductase from bovine heart mitochondria FEBS Lett. 286 1991 121 124
J.E. Cronan, I.M. Fearnley, and J.E. Walker Mammalian mitochondria contain a soluble acyl carrier protein FEBS Lett. 579 2005 4892 4896
U. Sackmann, R. Zensen, D. Rohlen, U. Jahnke, and H. Weiss The acyl-carrier protein in Neurospora crassa mitochondria is a subunit of NADH:ubiquinone reductase (complex I) Eur. J. Biochem. 200 1991 463 469
H. Angerer, M. Radermacher, M. Mańkowska, M. Steger, K. Zwicker, H. Heide, I. Wittig, U. Brandt, and V. Zickermann The LYR protein subunit NB4M/NDUFA6 of mitochondrial complex I anchors an acyl carrier protein and is essential for catalytic activity PNAS 111 2014 5207 5212
H.-P. Braun, and E. Zabaleta Carbonic anhydrase subunits of the mitochondrial NADH dehydrogenase complex (complex I) in plants Physiol. Plant. 129 2007 114 122
C. Kisker, H. Schindelin, B.E. Alber, J.G. Ferry, and D.C. Rees A left-hand beta-helix revealed by the crystal structure of a carbonic anhydrase from the archaeon Methanosarcina thermophila EMBO J. 15 1996 2323 2330
J.P. Córdoba, F. Marchetti, D. Soto, M.V. Martin, G.C. Pagnussat, and E. Zabaleta The CA domain of the respiratory complex I is required for normal embryogenesis in Arabidopsis thaliana J. Exp. Bot. 2015
D. Moreira, P. López-García, and K. Vickerman An updated view of kinetoplastid phylogeny using environmental sequences and a closer outgroup: proposal for a new classification of the class Kinetoplastea Int J Syst Evol Microbio 54 2004 1861 1875
A.G.B. Simpson, and A.J. Roger Protein phylogenies robustly resolve the deep-level relationships within Euglenozoa Mol. Phylogenet. Evol. 30 2004 201 212
E. Perez, M. Lapaille, H. Degand, L. Cilibrasi, A. Villavicencio-Queijeiro, P. Morsomme, D. Gonzalez-Halphen, M.C. Field, C. Remacle, D. Baurain, P. Cardol, The mitochondrial respiratory chain of the secondary green alga Euglena gracilis shares many additional subunits with parasitic Trypanosomatidae, Mitochondrion, 19 Pt B (2014) 338-349.
O.V. Karpova, and K.J. Newton A partially assembled complex I in NAD4-deficient mitochondria of maize Plant J. 17 1999 511 521
J.R. Marienfeld, and K.J. Newton The maize NCS2 abnormal growth mutant has a chimeric nad4-nad7 mitochondrial gene and is associated with reduced complex I function Genetics 138 1994 855 863
O.V. Karpova, E.V. Kuzmin, T.E. Elthon, and K.J. Newton Differential expression of alternative oxidase genes in maize mitochondrial mutants Plant Cell 14 2002 3271 3284
M. Pla, C. Mathieu, R. De Paepe, P. Chetrit, and F. Vedel Deletion of the last two exons of the mitochondrial nad7 gene results in lack of the NAD7 polypeptide in a Nicotiana sylvestris CMS mutant Mol. Gen. Genet. 248 1995 79 88
S. Gutierres, M. Sabar, C. Lelandais, P. Chetrit, P. Diolez, H. Degand, M. Boutry, F. Vedel, Y. de Kouchkovsky, and R. De Paepe Lack of mitochondrial and nuclear-encoded subunits of complex I and alteration of the respiratory chain in Nicotiana sylvestris mitochondrial deletion mutants Proc. Natl. Acad. Sci. U. S. A. 94 1997 3436 3441
S. Gutierres, B. Combettes, R. De Paepe, M. Mirande, C. Lelandais, F. Vedel, and P. Chetrit In the Nicotiana sylvestris CMSII mutant, a recombination-mediated change 5′ to the first exon of the mitochondrial nad1 gene is associated with lack of the NADH:ubiquinone oxidoreductase (complex I) NAD1 subunit Eur. J. Biochem. 261 1999 361 370
B. Pineau, C. Mathieu, C. Gerard-Hirne, R. De Paepe, and P. Chetrit Targeting the NAD7 subunit to mitochondria restores a functional complex I and a wild type phenotype in the Nicotiana sylvestris CMS II mutant lacking nad7 J. Biol. Chem. 280 2005 25994 26001
B.-h. Lee, H. Lee, L. Xiong, and J.-K. Zhu A mitochondrial complex I defect impairs cold-regulated nuclear gene expression Plant Cell 14 2002 1235 1251
B. Pineau, O. Layoune, A. Danon, and R. De Paepe l-galactono-1,4-lactone dehydrogenase is required for the accumulation of plant respiratory complex I J. Biol. Chem. 283 2008 32500 32505
C.C.d. Francs-Small, A.F.d. Longevialle, Y. Li, E. Lowe, S.K. Tanz, C. Smith, M.W. Bevan, and I. Small The pentatricopeptide repeat proteins TANG2 and ORGANELLE TRANSCRIPT PROCESSING439 are involved in the Splicing of the multipartite nad5 transcript encoding a subunit of mitochondrial Complex I Plant Physiol. 165 2014 1409 1416
C. Remacle, F. Duby, P. Cardol, and R.F. Matagne Mutations inactivating mitochondrial genes in Chlamydomonas reinhardtii Biochem. Soc. Trans. 29 2001 442 446
F. Duby, and R.F. Matagne Alteration of dark respiration and reduction of phototrophic growth in a mitochondrial DNA deletion mutant of Chlamydomonas lacking cob, nd4, and the 3′ end of nd5 Plant Cell 11 1999 115 126
T. Salinas, F. Duby, V. Larosa, N. Coosemans, N. Bonnefoy, P. Motte, L. Marechal-Drouard, and C. Remacle Co-evolution of mitochondrial tRNA import and codon usage determines translational efficiency in the green alga Chlamydomonas PLoS Genet. 8 2012 e1002946
M.M. Wydro, P. Sharma, J.M. Foster, K. Bych, E.H. Meyer, and J. Balk The evolutionarily conserved iron-sulfur protein INDH is required for complex I assembly and mitochondrial translation in Arabidopsis [corrected] Plant Cell 25 2013 4014 4027
C.C.d. Francs-Small, and I. Small Surrogate mutants for studying mitochondrially encoded functions Biochimie 100 2014 234 242
C. Remacle, M.R. Barbieri, P. Cardol, and P.P. Hamel Eukaryotic complex I: functional diversity and experimental systems to unravel the assembly process Mol. Gen. Genomics. 280 2008 93 110
S.J. Kerscher Diversity and origin of alternative NADH:ubiquinone oxidoreductases Biochim. Biophys. Acta 1459 2000 274 283
F. Distelmaier, W.J.H. Koopman, L.P. van den Heuvel, R.J. Rodenburg, E. Mayatepek, P.H.G.M. Willems, and J.A.M. Smeitink Mitochondrial complex I deficiency: from organelle dysfunction to clinical disease Brain 132 2009 833 842
H. Pagniez-Mammeri, S. Loublier, A. Legrand, P. Bénit, P. Rustin, and A. Slama Mitochondrial complex I deficiency of nuclear origin: I. Structural genes Mol. Genet. Metab. 105 2012 163 172
C. Dutilleul, S. Driscoll, G. Cornic, R. De Paepe, C.H. Foyer, and G. Noctor Functional mitochondrial complex I is required by tobacco leaves for optimal photosynthetic performance in photorespiratory conditions and during transients Plant Physiol. 131 2003 264 275
M. Sabar, R. De Paepe, and Y. de Kouchkovsky Complex I impairment, respiratory compensations, and photosynthetic decrease in nuclear and mitochondrial male sterile mutants of Nicotiana sylvestris Plant Physiol. 124 2000 1239 1250
C. Dutilleul, C. Lelarge, J.L. Prioul, R. De Paepe, C.H. Foyer, and G. Noctor Mitochondria-driven changes in leaf NAD status exert a crucial influence on the control of nitrate assimilation and the integration of carbon and nitrogen metabolism Plant Physiol. 139 2005 64 78
C. Dutilleul, M. Garmier, G. Noctor, C. Mathieu, P. Chetrit, C.H. Foyer, and R. de Paepe Leaf mitochondria modulate whole cell redox homeostasis, set antioxidant capacity, and determine stress resistance through altered signaling and diurnal regulation Plant Cell 15 2003 1212 1226
O.V. Karpova, and K.J. Newton A partially assembled complex I in ND4-deficient mitochondria of maize Plant J. 17 1999 511 521
K.J. Newton, and E.H. Coe Mitochondrial DNA changes in abnormal growth (nonchromosomal stripe) mutants of maize Proc. Natl. Acad. Sci. U. S. A. 83 1986 7363 7366
D.L. Roussell, D.L. Thompson, S.G. Pallardy, D. Miles, and K.J. Newton Chloroplast structure and function is altered in the NCS2 maize mitochondrial mutant Plant Physiol. 96 1991 232 238
S. Jiao, J. Thornsberry, T. Elthon, and K. Newton Biochemical and molecular characterization of photosystem I deficiency in the NCS6 mitochondrial mutant of maize Plant Mol. Biol. 57 2005 303 313
M.E. Breuer, P.H. Willems, J.A. Smeitink, W.J. Koopman, and M. Nooteboom Cellular and animal models for mitochondrial complex I deficiency: a focus on the NDUFS4 subunit IUBMB Life 65 2013 202 208
P. Cardol, G. Gloire, M. Havaux, C. Remacle, R. Matagne, and F. Franck Photosynthesis and state transitions in mitochondrial mutants of Chlamydomonas reinhardtii affected in respiration Plant Physiol. 133 2003 2010 2020
M. Duarte, N. Mota, L. Pinto, and A. Videira Inactivation of the gene coding for the 30.4-kDa subunit of respiratory chain NADH dehydrogenase: is the enzyme essential for Neurospora? Mol. Gen. Genet. 257 1998 368 375
U. Schulte, and H. Weiss Generation and characterization of NADH: ubiquinone oxidoreductase mutants in Neurospora crassa Methods Enzymol. 260 1995 3 14
H. Erhardt, S. Steimle, V. Muders, T. Pohl, J. Walter, and T. Friedrich Disruption of individual nuo-genes leads to the formation of partially assembled NADH:ubiquinone oxidoreductase (complex I) in Escherichia coli Biochim. Biophys. Acta 1817 2012 863 871
C. Lelandais, B. Albert, S. Gutierres, R. De Paepe, B. Godelle, F. Vedel, and P. Chetrit Organization and expression of the mitochondrial genome in the Nicotiana sylvestris CMSII mutant Genetics 150 1998 873 882
E. Zabaleta, M.V. Martin, and H.-P. Braun A basal carbon concentrating mechanism in plants? Plant Sci. 187 2012 97 104
J. Schimmeyer, R. Bock, and E.H. Meyer l-Galactono-1,4-lactone dehydrogenase is an Assembly Factor of the Membrane arm of Mitochondrial Complex I in Arabidopsis Plant Mol Biol 2015
L. Li, C.J. Nelson, C. Carrie, R.M. Gawryluk, C. Solheim, M.W. Gray, J. Whelan, and A.H. Millar Subcomplexes of ancestral respiratory complex I subunits rapidly turn over in vivo as productive assembly intermediates in Arabidopsis J. Biol. Chem. 288 2013 5707 5717
F. Villarreal, V. Martin, A. Colaneri, N. Gonzalez-Schain, M. Perales, M. Martin, C. Lombardo, H.P. Braun, C. Bartoli, and E. Zabaleta Ectopic expression of mitochondrial gamma carbonic anhydrase 2 causes male sterility by anther indehiscence Plant Mol. Biol. 70 2009 471 485
G. Parisi, M. Perales, M.S. Fornasari, A. Colaneri, N. Gonzalez-Schain, D. Gomez-Casati, S. Zimmermann, A. Brennicke, A. Araya, J.G. Ferry, J. Echave, and E. Zabaleta Gamma carbonic anhydrases in plant mitochondria Plant Mol. Biol. 55 2004 193 207
V. Martin, F. Villarreal, I. Miras, A. Navaza, A. Haouz, R.M. Gonzalez-Lebrero, S.B. Kaufman, and E. Zabaleta Recombinant plant gamma carbonic anhydrase homotrimers bind inorganic carbon FEBS Lett. 583 2009 3425 3430
J. Moroney, N. Jungnick, R. DiMario, and D. Longstreth Photorespiration and carbon concentrating mechanisms: two adaptations to high O2, low CO2 conditions Photosynth. Res. 117 2013 121 131
P. Schertl, S. Sunderhaus, J. Klodmann, G.E. Grozeff, C.G. Bartoli, and H.P. Braun l-galactono-1,4-lactone dehydrogenase (GLDH) forms part of three subcomplexes of mitochondrial complex I in Arabidopsis thaliana J. Biol. Chem. 287 2012 14412 14419
A.H. Millar, V. Mittova, G. Kiddle, J.L. Heazlewood, C.G. Bartoli, F.L. Theodoulou, and C.H. Foyer Control of ascorbate synthesis by respiration and its implications for stress responses Plant Physiol. 133 2003 443 447
M. McKenzie, and M.T. Ryan Assembly factors of human mitochondrial complex I and their defects in disease IUBMB Life 62 2010 497 502
B. Andrews, J. Carroll, S. Ding, I.M. Fearnley, and J.E. Walker Assembly factors for the membrane arm of human complex I Proc. Natl. Acad. Sci. U. S. A. 110 2013 18934 18939
V. Guarani, J. Paulo, B. Zhai, E.L. Huttlin, S.P. Gygi, and J.W. Harper TIMMDC1/C3orf1 functions as a membrane-embedded mitochondrial complex I assembly factor through association with the MCIA complex Mol. Cell. Biol. 34 2014 847 861
O. Zurita Rendón, L. Silva Neiva, F. Sasarman, and E.A. Shoubridge The arginine methyltransferase NDUFAF7 is essential for complex I assembly and early vertebrate embryogenesis Hum. Mol. Genet. 23 2014 5159 5170
L.E. Formosa, M. Mimaki, A.E. Frazier, M. McKenzie, T.L. Stait, D.R. Thorburn, D.A. Stroud, and M.T. Ryan Characterization of mitochondrial FOXRED1 in the assembly of respiratory chain complex I Hum. Mol. Genet. 24 2015 2952 2965
J.L. Heazlewood, J.S. Tonti-Filippini, A.M. Gout, D.A. Day, J. Whelan, and A.H. Millar Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins Plant Cell 16 2004 241 256
N.L. Taylor, J.L. Heazlewood, and A.H. Millar The Arabidopsis thaliana 2-D gel mitochondrial proteome: refining the value of reference maps for assessing protein abundance, contaminants and post-translational modifications Proteomics 11 2011 1720 1733
J. Klodmann, M. Senkler, C. Rode, and H.P. Braun Defining the protein complex proteome of plant mitochondria Plant Physiol. 157 2011 587 598
M.W. Murcha, D. Elhafez, R. Lister, J. Tonti-Filippini, M. Baumgartner, K. Philippar, C. Carrie, D. Mokranjac, J. Soll, and J. Whelan Characterization of the preprotein and amino acid transporter gene family in Arabidopsis Plant Physiol. 143 2007 199 212
S.K. Tanz, I. Castleden, C.M. Hooper, M. Vacher, I. Small, and H.A. Millar SUBA3: a database for integrating experimentation and prediction to define the SUBcellular location of proteins in Arabidopsis Nucleic Acids Res. 41 2013 D1185 D1191
O. Emanuelsson, H. Nielsen, S. Brunak, and G. von Heijne Predicting subcellular localization of proteins based on their N-terminal amino acid sequence J. Mol. Biol. 300 2000 1005 1016
A. Atteia, A. Adrait, S. Brugiere, M. Tardif, R. van Lis, O. Deusch, T. Dagan, L. Kuhn, B. Gontero, W. Martin, J. Garin, J. Joyard, and N. Rolland A proteomic survey of Chlamydomonas reinhardtii mitochondria sheds new light on the metabolic plasticity of the organelle and on the nature of the alpha-proteobacterial mitochondrial ancestor Mol. Biol. Evol. 26 2009 1533 1548
M. Tardif, A. Atteia, M. Specht, G. Cogne, N. Rolland, S. Brugiere, M. Hippler, M. Ferro, C. Bruley, G. Peltier, O. Vallon, and L. Cournac PredAlgo: a new subcellular localization prediction tool dedicated to green algae Mol. Biol. Evol. 29 2012 3625 3639
R.O. Vogel, J.A. Smeitink, and L.G. Nijtmans Human mitochondrial complex I assembly: a dynamic and versatile process Biochim. Biophys. Acta 1767 2007 1215 1227
M. Lapaille, A. Escobar-RamÃrez, H. Degand, D. Baurain, E. RodrÃguez-Salinas, N. Coosemans, M. Boutry, D. Gonzalez-Halphen, C. Remacle, and P. Cardol Atypical subunit composition of the chlorophycean mitochondrial F1FO-ATP synthase and role of Asa7 protein in stability and oligomycin resistance of the enzyme Mol.Biol. Evol. 27 2010 1630 1644
R. Kuffner, A. Rohr, A. Schmiede, C. Krull, and U. Schulte Involvement of two novel chaperones in the assembly of mitochondrial NADH:ubiquinone oxidoreductase (complex I) J. Mol. Biol. 283 1998 409 417
I. Ogilvie, N.G. Kennaway, and E.A. Shoubridge A molecular chaperone for mitochondrial complex I assembly is mutated in a progressive encephalopathy J. Clin. Invest. 115 2005 2784 2792
D.J. Pagliarini, S.E. Calvo, B. Chang, S.A. Sheth, S.B. Vafai, S.E. Ong, G.A. Walford, C. Sugiana, A. Boneh, W.K. Chen, D.E. Hill, M. Vidal, J.G. Evans, D.R. Thorburn, S.A. Carr, and V.K. Mootha A mitochondrial protein compendium elucidates complex I disease biology Cell 134 2008 112 123
I. Berger, Z. Ben-Neriah, T. Dor-Wolman, A. Shaag, A. Saada, S. Zenvirt, A. Raas-Rothschild, M. Nadjari, K.H. Kaestner, and O. Elpeleg Early prenatal ventriculomegaly due to an AIFM1 mutation identified by linkage analysis and whole exome sequencing Mol. Genet. Metab. 104 2011 517 520
J. Nouws, L.G. Nijtmans, J.A. Smeitink, and R.O. Vogel Assembly factors as a new class of disease genes for mitochondrial complex I deficiency: cause, pathology and treatment options Brain 135 2012 12 22
R. Cossard, M. Esposito, C.H. Sellem, L. Pitayu, C. Vasnier, A. Delahodde, and E.P. Dassa Caenorhabditis elegans expressing the Saccharomyces cerevisiae NADH alternative dehydrogenase Ndi1p, as a tool to identify new genes involved in complex I related diseases Front. Genet. 6 2015 206
R.O. Vogel, R.J. Janssen, M.A. van den Brand, C.E. Dieteren, S. Verkaart, W.J. Koopman, P.H. Willems, W. Pluk, L.P. van den Heuvel, J.A. Smeitink, and L.G. Nijtmans Cytosolic signaling protein Ecsit also localizes to mitochondria where it interacts with chaperone NDUFAF1 and functions in complex I assembly Genes Dev. 21 2007 615 624
R.O. Vogel, M.A. van den Brand, R.J. Rodenburg, L.P. van den Heuvel, M. Tsuneoka, J.A. Smeitink, and L.G. Nijtmans Investigation of the complex I assembly chaperones B17.2L and NDUFAF1 in a cohort of CI deficient patients Mol. Genet. Metab. 91 2007 176 182
R.S. Vartak, M.K. Semwal, and Y. Bai An update on complex I assembly: the assembly of players J. Bioenerg. Biomembr. 46 2014 323 328
M. Gerards, W. Sluiter, B.J. van den Bosch, E. de Wit, C.M. Calis, M. Frentzen, H. Akbari, K. Schoonderwoerd, H.R. Scholte, R.J. Jongbloed, A.T. Hendrickx, I.F. de Coo, and H.J. Smeets Defective Complex I Assembly due to C20orf7 Mutations as a New Cause of Leigh Syndrome J. Med. Genet. 2009
A. Saada, S. Edvardson, M. Rapoport, A. Shaag, K. Amry, C. Miller, H. Lorberboum-Galski, and O. Elpeleg C6ORF66 is an assembly factor of mitochondrial complex I Am. J. Hum. Genet. 82 2008 32 38
A. Saada, R.O. Vogel, S.J. Hoefs, M.A. van den Brand, H.J. Wessels, P.H. Willems, H. Venselaar, A. Shaag, F. Barghuti, O. Reish, M. Shohat, M.A. Huynen, J.A. Smeitink, L.P. van den Heuvel, and L.G. Nijtmans Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)-interacting complex I assembly protein, cause fatal neonatal mitochondrial disease Am. J. Hum. Genet. 84 2009 718 727
H. Heide, L. Bleier, M. Steger, J. Ackermann, S. Drose, B. Schwamb, M. Zornig, A.S. Reichert, I. Koch, I. Wittig, and U. Brandt Complexome profiling identifies TMEM126B as a component of the mitochondrial complex I assembly complex Cell Metab. 16 2012 538 549
S. Carilla-Latorre, M.E. Gallardo, S.J. Annesley, J. Calvo-Garrido, O. Grana, S.L. Accari, P.K. Smith, A. Valencia, R. Garesse, P.R. Fisher, and R. Escalante MidA is a putative methyltransferase that is required for mitochondrial complex I function J. Cell Sci. 123 2010 1674 1683
V.F. Rhein, J. Carroll, S. Ding, I.M. Fearnley, and J.E. Walker NDUFAF7 methylates arginine 85 in the NDUFS2 subunit of human complex I J. Biol. Chem. 288 2013 33016 33026
M. McKenzie, E.J. Tucker, A.G. Compton, M. Lazarou, C. George, D.R. Thorburn, and M.T. Ryan Mutations in the gene encoding C8orf38 block complex I assembly by inhibiting production of the mitochondria-encoded subunit ND1 J. Mol. Biol. 414 2011 413 426
O. Zurita Rendon, and E.A. Shoubridge Early complex I assembly defects result in rapid turnover of the ND1 subunit Hum. Mol. Genet. 21 2012 3815 3824
K. Zhang, Z. Li, M. Jaiswal, V. Bayat, B. Xiong, H. Sandoval, W.L. Charng, G. David, C. Haueter, S. Yamamoto, B.H. Graham, and H.J. Bellen The C8ORF38 homologue Sicily is a cytosolic chaperone for a mitochondrial complex I subunit J. Cell Biol. 200 2013 807 820
K. Bych, S. Kerscher, D.J. Netz, A.J. Pierik, K. Zwicker, M.A. Huynen, R. Lill, U. Brandt, and J. Balk The iron-sulphur protein Ind1 is required for effective complex I assembly EMBO J. 27 2008 1736 1746
A.D. Sheftel, O. Stehling, A.J. Pierik, D.J. Netz, S. Kerscher, H.P. Elsasser, I. Wittig, J. Balk, U. Brandt, and R. Lill Human ind1, an iron-sulfur cluster assembly factor for respiratory complex I Mol. Cell. Biol. 29 2009 6059 6073
S.H. Kevelam, R.J. Rodenburg, N.I. Wolf, P. Ferreira, R.J. Lunsing, L.G. Nijtmans, A. Mitchell, H.A. Arroyo, D. Rating, A. Vanderver, C.G.M. van Berkel, T.E.M. Abbink, P. Heutink, and M.S. van der Knaap NUBPL mutations in patients with complex I deficiency and a distinct MRI pattern Neurology 80 2013 1577 1583
V.S. Chakrabarti, M. Mikolajczyk, F. Boscaro, and V. Calderone Human Ind1 expression causes over-expression of E. coli beta-lactamase ampicillin resistance protein Protein Expr. Purif. 104C 2014 26 33
N.G. Leferink, W.A. van den Berg, and W.J. van Berkel l-Galactono-gamma-lactone dehydrogenase from Arabidopsis thaliana, a flavoprotein involved in vitamin C biosynthesis FEBS J. 275 2008 713 726
E. Siendones, J.A. Gonzalez-Reyes, C. Santos-Ocana, P. Navas, and C.R. F Biosynthesis of ascorbic acid in kidney bean. l-Galactono-gamma-lactone dehydrogenase is an intrinsic protein located at the mitochondrial inner membrane Plant Physiol. 120 1999 907 912
C.G. Bartoli, G.M. Pastori, and C.H. Foyer Ascorbate biosynthesis in mitochondria is linked to the electron transport chain between complexes III and IV Plant Physiol. 123 2000 335 344
L.W. Mapson, and E. Breslow Biological synthesis of ascorbic acid: l-galactono-gamma-lactone dehydrogenase Biochem. J. 68 1958 395 406
K. Oba, S. Ishikawa, M. Nishikawa, H. Mizuno, and T. Yamamoto Purification and properties of l-galactono-gamma-lactone dehydrogenase, a key enzyme for ascorbic acid biosynthesis, from sweet potato roots J. Biochem. 117 1995 120 124
T. Imai, S. Karita, G. Shiratori, M. Hattori, T. Nunome, K. Oba, and M. Hirai l-galactono-gamma-lactone dehydrogenase from sweet potato: purification and cDNA sequence analysis Plant Cell Physiol. 39 1998 1350 1358
Y. Yabuta, K. Yoshimura, T. Takeda, and S. Shigeoka Molecular characterization of tobacco mitochondrial l-galactono-gamma-lactone dehydrogenase and its expression in Escherichia coli Plant Cell Physiol 41 2000 666 675
K. Kuhn, C. Carrie, E. Giraud, Y. Wang, E.H. Meyer, R. Narsai, C.C.d. Francs-Small, B. Zhang, M.W. Murcha, and J. Whelan The RCC1 family protein RUG3 is required for splicing of nad2 and complex I biogenesis in mitochondria of Arabidopsis thaliana Plant J. 67 2011 1067 1080
D.R. Gallie l-ascorbic acid: a multifunctional molecule supporting plant growth and development Scientifica 2013 2013 24
I. Marques, M. Duarte, J. Assunção, A.V. Ushakova, and A. Videira Composition of complex I from Neurospora crassa and disruption of two "accessory" subunits. 1707 2-3 2005 211 220
W.L. Araújo, K. Ishizaki, A. Nunes-Nesi, T.R. Larson, T. Tohge, I. Krahnert, S. Witt, T. Obata, N. Schauer, I.A. Graham, C.J. Leaver, and A.R. Fernie Identification of the 2-hydroxyglutarate and isovaleryl-CoA dehydrogenases as alternative electron donors linking lysine catabolism to the electron transport chain of Arabidopsis mitochondria. Plant Cell. 22 5 2010 1549 1563
