No full text
Article (Scientific journals)
The Determination of Megakaryocyte Ploidy
Paulus, Jean-Michel; Senterre, Jacques; von Frenckell, Rémy
1990In International Journal of Cell Cloning, 8 (4), p. 227-35
 

Files


Full Text
No document available.

Send to



Details



Keywords :
microphotometry; flow cytometry; fluorochrome; data analysis
Abstract :
[en] Methods which have been used to determine megakaryocyte ploidy in animals and humans are reviewed. Although the number of megakaryocyte nuclear units counted in bone marrow squashes is roughly proportional to ploidy, accurate determinations of DNA content require the use of microphotometry or flow cytometry. New techniques should make it possible to distinguish polyploidizing megakaryoblasts from promegakaryocytes and mature megakaryocytes which have arrested polyploidization. Only the latter should be included in histograms of the number of endoduplications, since only those have expressed their full polyploidization potential. Statistical techniques are available for analysis and comparison of both raw ploidy distributions or histograms of endoduplication numbers.
Disciplines :
Hematology
Author, co-author :
Paulus, Jean-Michel ;  Université de Liège - ULiège > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine)
Senterre, Jacques 
von Frenckell, Rémy ;  Université de Liège - ULiège > Unité de Psychiatrie Biologique et de Psychopharmacologie
Language :
English
Title :
The Determination of Megakaryocyte Ploidy
Publication date :
July 1990
Journal title :
International Journal of Cell Cloning
ISSN :
0737-1454
Publisher :
AlphaMed Press Inc., United States - Ohio
Volume :
8
Issue :
4
Pages :
227-35
Available on ORBi :
since 09 June 2016

Statistics


Number of views
25 (2 by ULiège)
Number of downloads
0 (0 by ULiège)

Scopus citations®
 
1
Scopus citations®
without self-citations
1
OpenCitations
 
1

Bibliography


Similar publications



Contact ORBi