Article (Scientific journals)
Prospective validation obtained in a similar group of patients and with similar high throughput biological tests failed to confirm signatures for prediction of response to chemotherapy and survival in advanced NSCLC: a prospective study from the European Lung Cancer Working Party
Berghmans, Thierry; Ameye, Lieveke; Lafitte, Jean-Jacques et al.
2015In Frontiers in Oncology, 4
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Keywords :
non-small cell lung cancer; mRNA; miRNA; chemotherapy; survival
Abstract :
[en] Cisplatin doublets are standard 1st line treatment for advanced non-small cell lung cancer (NSCLC), without accurate predictor for response and survival, but important toxicity. Our aimswere to identify predictive (for response) and prognostic (for survival) biological signatures in patients with NSCLC using messenger RNAs (mRNA) and miRNA expression.
Disciplines :
Oncology
Author, co-author :
Berghmans, Thierry
Ameye, Lieveke
Lafitte, Jean-Jacques
Colinet, Benoît
Cortot, Alexis
CsToth, Ingrid
Holbrechts, Stéphane
Lecomte, Jacques
Mascaux, Céline
Meert, Anne-Pascale
Paesmans, Marianne
Richez, Michel
Scherpereel, Arnaud
Tulippe, Christian
Willems, Luc  ;  Université de Liège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Biologie cell. et moléc.
Dernies, Tiffany
Leclercq, Nathalie
Sculier, Jean-Paul
More authors (8 more) Less
Language :
English
Title :
Prospective validation obtained in a similar group of patients and with similar high throughput biological tests failed to confirm signatures for prediction of response to chemotherapy and survival in advanced NSCLC: a prospective study from the European Lung Cancer Working Party
Publication date :
28 January 2015
Journal title :
Frontiers in Oncology
eISSN :
2234-943X
Publisher :
Frontiers Media, Lausanne, Switzerland
Volume :
4
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 20 December 2015

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