Effects of Dairy Products Consumption on Health: Benefits and Beliefs-A Commentary from the Belgian Bone Club and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases.
[en] Dairy products provide a package of essential nutrients that is difficult to obtain in low-dairy or dairy-free diets, and for many people it is not possible to achieve recommended daily calcium intakes with a dairy-free diet. Despite the established benefits for bone health, some people avoid dairy in their diet due to beliefs that dairy may be detrimental to health, especially in those with weight management issues, lactose intolerance, osteoarthritis, rheumatoid arthritis, or trying to avoid cardiovascular disease. This review provides information for health professionals to enable them to help their patients make informed decisions about consuming dairy products as part of a balanced diet. There may be a weak association between dairy consumption and a possible small weight reduction, with decreases in fat mass and waist circumference and increases in lean body mass. Lactose intolerant individuals may not need to completely eliminate dairy products from their diet, as both yogurt and hard cheese are well tolerated. Among people with arthritis, there is no evidence for a benefit to avoid dairy consumption. Dairy products do not increase the risk of cardiovascular disease, particularly if low fat. Intake of up to three servings of dairy products per day appears to be safe and may confer a favourable benefit with regard to bone health.
Disciplines :
Public health, health care sciences & services
Author, co-author :
Rozenberg, Serge
Body, Jean-Jacques
Bruyère, Olivier ; Université de Liège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Bergmann, Pierre
Brandi, Maria Luisa
Cooper, Cyrus
Devogelaer, Jean-Pierre
Gielen, Evelien
Goemaere, Stefan
Kaufman, Jean-Marc
Rizzoli, René
Reginster, Jean-Yves ; Université de Liège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Language :
English
Title :
Effects of Dairy Products Consumption on Health: Benefits and Beliefs-A Commentary from the Belgian Bone Club and the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases.
Publication date :
2016
Journal title :
Calcified Tissue International
ISSN :
0171-967X
eISSN :
1432-0827
Publisher :
Springer Verlag, New York, United States - New York
Smit E, Nieto FJ, Crespo CJ, Mitchell P (1999) Estimates of animal and plant protein intake in US adults: results from the Third National Health and Nutrition Examination Survey, 1988–1991. J Am Diet Assoc 99(7):813–820. doi:10.1016/S0002-8223(99)00193-5
Feskanich D, Willett WC, Colditz GA (2003) Calcium, vitamin D, milk consumption, and hip fractures: a prospective study among postmenopausal women. Am J Clin Nutr 77(2):504–511
Chevalley T, Bonjour JP, Ferrari S, Rizzoli R (2008) High-protein intake enhances the positive impact of physical activity on BMC in prepubertal boys. J Bone Miner Res 23(1):131–142. doi:10.1359/jbmr.070907
Vissers PA, Streppel MT, Feskens EJ, de Groot LC (2011) The contribution of dairy products to micronutrient intake in the Netherlands. J Am Coll Nutr 30(5 Suppl 1):415S–421S
Skinner ML, Simpson JA, Buchholz AC (2011) Dietary and total calcium intakes are associated with lower percentage total body and truncal fat in young, healthy adults. J Am Coll Nutr 30(6):484–490
Gueguen L, Pointillart A (2000) The bioavailability of dietary calcium. J Am Coll Nutr 19(2 Suppl):119S–136S
Gueguen L (2001) Calcium, phosphorus. Apports Nutritionnels Conseillees pour la Population Francaise (Recommended nutrient intakes for the French population). Tech & Doc, Paris
Bonjour JP (2011) Calcium and phosphate: a duet of ions playing for bone health. J Am Coll Nutr 30(5 Suppl 1):438S–448S
Elmadfa I (2009) European Nutrition and Health Report 2009. Forum Nutr. Basel, Switzerland, vol 69. Karger, New York
Lopes AC, Caiaffa WT, Sichieri R, Mingoti SA, Lima-Costa MF (2005) Nutrient consumption by adults and seniors in a population-based study: the Bambui Project. Cadernos de saude publica 21(4):1201–1209. doi:10.1590/S0102-311x2005000400022
Heaney RP (2009) Dairy and bone health. J Am Coll Nutr 28(Suppl 1):82S–90S
Caroli A, Poli A, Ricotta D, Banfi G, Cocchi D (2011) Invited review: dairy intake and bone health: a viewpoint from the state of the art. J Dairy Sci 94(11):5249–5262. doi:10.3168/jds.2011-4578
Agriculture USDo (2010) Dietary guidelines for Americans, 7th edn. Agriculture USDo, Washington, DC
Agriculture USDo (2013) USDA National Nutrient Database for Standard Reference, Release 26
Fulgoni VL 3rd, Keast DR, Auestad N, Quann EE (2011) Nutrients from dairy foods are difficult to replace in diets of Americans: food pattern modeling and an analyses of the National Health and Nutrition Examination Survey 2003–2006. Nutr Res 31(10):759–765. doi:10.1016/j.nutres.2011.09.017
Marcoe K, Juan W, Yamini S, Carlson A, Britten P (2006) Development of food group composites and nutrient profiles for the MyPyramid Food Guidance System. J Nutr Educ Behav 38(6 Suppl):S93–S107. doi:10.1016/j.jneb.2006.05.014
Gao X, Wilde PE, Lichtenstein AH, Tucker KL (2006) Meeting adequate intake for dietary calcium without dairy foods in adolescents aged 9 to 18 years (National Health and Nutrition Examination Survey 2001–2002). J Am Diet Assoc 106(11):1759–1765. doi:10.1016/j.jada.2006.08.019
Weaver CM (2009) Should dairy be recommended as part of a healthy vegetarian diet? Point. Am J Clin Nutr 89(5):1634S–1637S. doi:10.3945/ajcn.2009.26736O
Keller JL, Lanou A, Barnard ND (2002) The consumer cost of calcium from food and supplements. J Am Diet Assoc 102(11):1669–1671
Weaver CM, Proulx WR, Heaney R (1999) Choices for achieving adequate dietary calcium with a vegetarian diet. Am J Clin Nutr 70:543S–548S
Rizzoli R (2008) Nutrition: its role in bone health. Best Pract Res Clin Endocrinol Metab 22(5):813–829. doi:10.1016/j.beem.2008.08.005
Cheng S, Lyytikainen A, Kroger H, Lamberg-Allardt C, Alen M, Koistinen A, Wang QJ, Suuriniemi M, Suominen H, Mahonen A, Nicholson PH, Ivaska KK, Korpela R, Ohlsson C, Vaananen KH, Tylavsky F (2005) Effects of calcium, dairy product, and vitamin D supplementation on bone mass accrual and body composition in 10-12-y-old girls: a 2-y randomized trial. Am J Clin Nutr 82(5):1115–1126
Li Y, Tome D, Desjeux JF (1989) Indirect effect of casein phosphopeptides on calcium absorption in rat ileum in vitro. Reprod Nutr Dev 29(2):227–233
Bonjour JP, Kraenzlin M, Levasseur R, Warren M, Whiting S (2013) Dairy in adulthood: from foods to nutrient interactions on bone and skeletal muscle health. J Am Coll Nutr 32(4):251–263. doi:10.1080/07315724.2013.816604
Bailey RL, Dodd KW, Goldman JA, Gahche JJ, Dwyer JT, Moshfegh AJ, Sempos CT, Picciano MF (2010) Estimation of total usual calcium and vitamin D intakes in the United States. J Nutr 140(4):817–822
Manios Y, Moschonis G, Trovas G, Lyritis GP (2007) Changes in biochemical indexes of bone metabolism and bone mineral density after a 12-mo dietary intervention program: the Postmenopausal Health Study. Am J Clin Nutr 86(3):781–789
Moschonis G, Katsaroli I, Lyritis GP, Manios Y (2010) The effects of a 30-month dietary intervention on bone mineral density: the Postmenopausal Health Study. Br J Nutr 104(1):100–107. doi:10.1017/S000711451000019X
Prince R, Devine A, Dick I, Criddle A, Kerr D, Kent N, Price R, Randell A (1995) The effects of calcium supplementation (milk powder or tablets) and exercise on bone density in postmenopausal women. J Bone Miner Res 10(7):1068–1075
Body JJ, Bergmann P, Boonen S, Boutsen Y, Bruyere O, Devogelaer JP, Goemaere S, Hollevoet N, Kaufman JM, Milisen K, Rozenberg S, Reginster JY (2011) Non-pharmacological management of osteoporosis: a consensus of the Belgian Bone Club. Osteoporos Int 22(11):2769–2788. doi:10.1007/s00198-011-1545-x
Kanis JA, McCloskey EV, Johansson H, Cooper C, Rizzoli R, Reginster JY, Scientific Advisory Board of the European Society for C, Economic Aspects of O, Osteoarthritis, the Committee of Scientific Advisors of the International Osteoporosis F (2013) European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporos Int 24(1):23–57. doi:10.1007/s00198-012-2074-y
Sunyecz JA (2008) The use of calcium and vitamin D in the management of osteoporosis. Ther Clin Risk Manag 4(4):827–836
Rizzoli R, Bianchi ML, Garabedian M, McKay HA, Moreno LA (2010) Maximizing bone mineral mass gain during growth for the prevention of fractures in the adolescents and the elderly. Bone 46(2):294–305. doi:10.1016/j.bone.2009.10.005
Ferrari S, Rizzoli R, Bonjour JP (1999) Genetic aspects of osteoporosis. Curr Opin Rheumatol 11(4):294–300
Rizzoli R (2014) Dairy products, yogurts, and bone health. Am J Clin Nutr 99(5 Suppl):1256S–1262S. doi:10.3945/ajcn.113.073056
Ganpule A, Yajnik CS, Fall CH, Rao S, Fisher DJ, Kanade A, Cooper C, Naik S, Joshi N, Lubree H, Deshpande V, Joglekar C (2006) Bone mass in Indian children–relationships to maternal nutritional status and diet during pregnancy: the Pune Maternal Nutrition Study. J Clin Endocrinol Metab 91(8):2994–3001. doi:10.1210/jc.2005-2431
Cole ZA, Gale CR, Javaid MK, Robinson SM, Law C, Boucher BJ, Crozier SR, Godfrey KM, Dennison EM, Cooper C (2009) Maternal dietary patterns during pregnancy and childhood bone mass: a longitudinal study. J Bone Miner Res 24(4):663–668. doi:10.1359/jbmr.081212
Dror DK, Allen LH (2014) Dairy product intake in children and adolescents in developed countries: trends, nutritional contribution, and a review of association with health outcomes. Nutr Rev 72(2):68–81. doi:10.1111/nure.12078
Goulding A, Rockell JE, Black RE, Grant AM, Jones IE, Williams SM (2004) Children who avoid drinking cow’s milk are at increased risk for prepubertal bone fractures. J Am Diet Assoc 104(2):250–253. doi:10.1016/j.jada.2003.11.008
Konstantynowicz J, Nguyen TV, Kaczmarski M, Jamiolkowski J, Piotrowska-Jastrzebska J, Seeman E (2007) Fractures during growth: potential role of a milk-free diet. Osteoporos Int 18(12):1601–1607. doi:10.1007/s00198-007-0397-x
Du X, Zhu K, Trube A, Zhang Q, Ma G, Hu X, Fraser DR, Greenfield H (2004) School-milk intervention trial enhances growth and bone mineral accretion in Chinese girls aged 10–12 years in Beijing. Br J Nutr 92(1):159–168. doi:10.1079/BJN20041118
Winzenberg T, Shaw K, Fryer J, Jones G (2006) Effects of calcium supplementation on bone density in healthy children: meta-analysis of randomised controlled trials. BMJ 333(7572):775. doi:10.1136/bmj.38950.561400.55
Huncharek M, Muscat J, Kupelnick B (2008) Impact of dairy products and dietary calcium on bone-mineral content in children: results of a meta-analysis. Bone 43(2):312–321. doi:10.1016/j.bone.2008.02.022
Bonjour JP, Carrie AL, Ferrari S, Clavien H, Slosman D, Theintz G, Rizzoli R (1997) Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial. J Clin Invest 99(6):1287–1294. doi:10.1172/JCI119287
Chevalley T, Bonjour JP, Ferrari S, Hans D, Rizzoli R (2005) Skeletal site selectivity in the effects of calcium supplementation on areal bone mineral density gain: a randomized, double-blind, placebo-controlled trial in prepubertal boys. J Clin Endocrinol Metab 90(6):3342–3349. doi:10.1210/jc.2004-1455
Bonjour JP, Chevalley T, Ammann P, Slosman D, Rizzoli R (2001) Gain in bone mineral mass in prepubertal girls 3.5 years after discontinuation of calcium supplementation: a follow-up study. Lancet 358(9289):1208–1212. doi:10.1016/S0140-6736(01)06342-5
Ross AC, Manson JE, Abrams SA, Aloia JF, Brannon PM, Clinton SK, Durazo-Arvizu RA, Gallagher JC, Gallo RL, Jones G, Kovacs CS, Mayne ST, Rosen CJ, Shapses SA (2011) The 2011 report on dietary reference intakes for calcium and vitamin D from the Institute of Medicine: what clinicians need to know. J Clin Endocrinol Metab 96(1):53–58. doi:10.1210/jc.2010-2704
Okano T (2003) Recommended daily allowance and dietary reference intakes for vitamin D and calcium in Japanese. Clin Calcium 13(7):876–881. doi:CliCa0307876881
Theobald HE (2005) Dietary calcium and health - http://www.nutrition.org.uk/attachments/105_Dietary%20calcium%20and%20health.pdf
https://www.nrv.gov.au/nutrients/calcium
Rizzoli R, Stevenson JC, Bauer JM, van Loon LJC, Walrand S, Kanis JA, Cooper C, Brandi M-L, Diez-Perez A, Reginster J-Y, Force ftET (2014) The role of dietary protein and vitamin D in maintaining musculoskeletal health in postmenopausal women: A consensus statement from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO). Maturitas 79:122–132. doi:10.1016/j.maturitas.2014.07.005
Tang BMP, Eslick GD, Nowson C, Smith C, Bensoussan A (2007) Use of calcium or calcium in combination with vitamin D supplementation to prevent fractures and bone loss in people aged 50 years and older: a meta-analysis. Lancet 370(9588):657–666. doi:10.1016/s0140-6736(07)61342-7
Boonen S, Lips P, Bouillon R, Bischoff-Ferrari HA, Vanderschueren D, Haentjens P (2007) Need for additional calcium to reduce the risk of hip fracture with vitamin d supplementation: evidence from a comparative metaanalysis of randomized controlled trials. J Clin Endocrinol Metab 92(4):1415–1423. doi:10.1210/jc.2006-1404
Nowson CA (2010) Prevention of fractures in older people with calcium and vitamin D. Nutrients 2(9):975–984
McCarron DA, Heaney RP (2004) Estimated healthcare savings associated with adequate dairy food intake. Am J Hypertens 17(1):88–97
Lotters FJ, Lenoir-Wijnkoop I, Fardellone P, Rizzoli R, Rocher E, Poley MJ (2013) Dairy foods and osteoporosis: an example of assessing the health-economic impact of food products. Osteoporos Int 24(1):139–150. doi:10.1007/s00198-012-1998-6
Schurch MA, Rizzoli R, Slosman D, Vadas L, Vergnaud P, Bonjour JP (1998) Protein supplements increase serum insulin-like growth factor-I levels and attenuate proximal femur bone loss in patients with recent hip fracture. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 128(10):801–809
Munger RG, Cerhan JR, Chiu BC (1999) Prospective study of dietary protein intake and risk of hip fracture in postmenopausal women. Am J Clin Nutr 69(1):147–152
Wengreen HJ, Munger RG, West NA, Cutler DR, Corcoran CD, Zhang J, Sassano NE (2004) Dietary protein intake and risk of osteoporotic hip fracture in elderly residents of Utah. J Bone Miner Res 19(4):537–545. doi:10.1359/jbmr.040208
Darling AL, Millward DJ, Torgerson DJ, Hewitt CE, Lanham-New SA (2009) Dietary protein and bone health: a systematic review and meta-analysis. Am J Clin Nutr 90(6):1674–1692. doi:10.3945/ajcn.2009.27799
Barzel US, Massey LK (1998) Excess dietary protein can adversely affect bone. J Nutr 128(6):1051–1053
Frassetto L, Morris RC Jr, Sellmeyer DE, Todd K, Sebastian A (2001) Diet, evolution and aging–the pathophysiologic effects of the post-agricultural inversion of the potassium-to-sodium and base-to-chloride ratios in the human diet. Eur J Nutr 40(5):200–213
Sellmeyer DE, Stone KL, Sebastian A, Cummings SR (2001) A high ratio of dietary animal to vegetable protein increases the rate of bone loss and the risk of fracture in postmenopausal women. Study of Osteoporotic Fractures Research Group. Am J Clin Nutr 73(1):118–122
Bonjour JP (2013) Nutritional disturbance in acid-base balance and osteoporosis: a hypothesis that disregards the essential homeostatic role of the kidney. Br J Nutr 110(7):1168–1177
Fenton TR, Tough SC, Lyon AW, Eliasziw M, Hanley DA (2011) Causal assessment of dietary acid load and bone disease: a systematic review & meta-analysis applying Hill’s epidemiologic criteria for causality. Nutr J 10:41. doi:10.1186/1475-2891-10-41
Calvez J, Poupin N, Chesneau C, Lassale C, Tome D (2012) Protein intake, calcium balance and health consequences. Eur J Clin Nutr 66(3):281–295. doi:10.1038/ejcn.2011.196
Thorpe MP, Jacobson EH, Layman DK, He X, Kris-Etherton PM, Evans EM (2008) A diet high in protein, dairy, and calcium attenuates bone loss over twelve months of weight loss and maintenance relative to a conventional high-carbohydrate diet in adults. J Nutr 138(6):1096–1100
Jehle S, Hulter HN, Krapf R (2013) Effect of potassium citrate on bone density, microarchitecture, and fracture risk in healthy older adults without osteoporosis: a randomized controlled trial. J Clin Endocrinol Metab 98(1):207–217. doi:10.1210/jc.2012-3099
Bruyère O, Rizzoli R, Coxam V, Avouac B, Chevalier T, Fabien-Soulé V, Kanis JA, Kaufman JM, Tsouderos Y, Reginster JY (2012) Assessment of health claims in the field of bone: a view of the Group for the Respect of Ethics and Excellence in Science (GREES). Osteoporos Int 23(1):193–199
Prentice A (2004) Diet, nutrition and the prevention of osteoporosis. Public Health Nutr 7(1A):227–243
Kanis JA, Odén A, McCloskey EV, Johansson H, Wahl DA, Cooper C (2012) A systematic review of hip fracture incidence and probability of fracture worldwide. Osteoporos Int 23(9):2239–2256
Prentice AM (2014) Dairy products in global public health. Am J Clin Nutr 99(5 Suppl):1212S–1216S. doi:10.3945/ajcn.113.073437
Olausson H, Goldberg GR, Laskey MA, Schoenmakers I, Jarjou LM, Prentice A (2012) Calcium economy in human pregnancy and lactation. Nutr Res Rev 25(1):40–67. doi:10.1017/s0954422411000187
Bischoff-Ferrari HA, Dawson-Hughes B, Baron JA, Kanis JA, Orav EJ, Staehelin HB, Kiel DP, Burckhardt P, Henschkowski J, Spiegelman D, Li R, Wong JB, Feskanich D, Willett WC (2011) Milk intake and risk of hip fracture in men and women: a meta-analysis of prospective cohort studies. J Bone Miner Res 26(4):833–839. doi:10.1002/jbmr.279
Feskanich D, Willett WC, Stampfer MJ, Colditz GA (1997) Milk, dietary calcium, and bone fractures in women: a 12-year prospective study. Am J Public Health 87(6):992–997
Sahni S, Tucker KL, Kiel DP, Quach L, Casey VA, Hannan MT (2013) Milk and yogurt consumption are linked with higher bone mineral density but not with hip fracture: the Framingham Offspring Study. Arch Osteoporos 8(1–2):119. doi:10.1007/s11657-013-0119-2
Sahni S, Mangano KM, Tucker KL, Kiel DP, Casey VA, Hannan MT (2014) Protective association of milk intake on the risk of hip fracture: results from the Framingham Original Cohort. J Bone Miner Res 29(8):1756–1762
Michaelsson K, Melhus H, Bellocco R, Wolk A (2003) Dietary calcium and vitamin D intake in relation to osteoporotic fracture risk. Bone 32(6):694–703
Michaëlsson K, Wolk A, Langenskiöld S, Basu S, Warensjö Lemming E, Melhus H, Byberg L (2014) Milk intake and risk of mortality and fractures in women and men: cohort studies. BMJ 349:g6015
Livsmedelsverket (2009) The National Food Agency, Sweden. Berikning av mjölk med vitamin A (Vitamin A fortification of milk). LIVSMEDELSVERKET 2009-12-11 Nutritionsavdelningen. Available from: http://www.slv.se/upload/dokument/mat/vitaminermineraler/Vitamin%20A%20berikning%20av%20mj%C3%B6lk.pdf. Accessed 05 Jan 2014
Bultink IE, Lems WF (2013) Osteoarthritis and osteoporosis: what is the overlap? Curr Rheumatol Rep 15(5):328
Lanou AJ, Barnard ND (2008) Dairy and weight loss hypothesis: an evaluation of the clinical trials. Nutr Rev 66(5):272–279. doi:10.1111/j.1753-4887.2008.00032.x
Trowman R, Dumville JC, Hahn S, Torgerson DJ (2006) A systematic review of the effects of calcium supplementation on body weight. Br J Nutr 95(6):1033–1038
Huang TT, McCrory MA (2005) Dairy intake, obesity, and metabolic health in children and adolescents: knowledge and gaps. Nutr Rev 63(3):71–80
Winzenberg T, Shaw K, Fryer J, Jones G (2007) Calcium supplements in healthy children do not affect weight gain, height, or body composition. Obesity (Silver Spring, Md) 15(7):1789–1798. doi:10.1038/oby.2007.213
Mozaffarian D, Hao T, Rimm EB, Willett WC, Hu FB (2011) Changes in diet and lifestyle and long-term weight gain in women and men. N Engl J Med 364(25):2392–2404. doi:10.1056/NEJMoa1014296
Abargouei AS, Janghorbani M, Salehi-Marzijarani M, Esmaillzadeh A (2012) Effect of dairy consumption on weight and body composition in adults: a systematic review and meta-analysis of randomized controlled clinical trials. Int J Obes 36(12):1485–1493. doi:10.1038/ijo.2011.269
Chen M, Pan A, Malik VS, Hu FB (2012) Effects of dairy intake on body weight and fat: a meta-analysis of randomized controlled trials. Am J Clin Nutr 96(4):735–747. doi:10.3945/ajcn.112.037119
Louie JC, Flood VM, Hector DJ, Rangan AM, Gill TP (2011) Dairy consumption and overweight and obesity: a systematic review of prospective cohort studies. Obes Rev 12(7):e582–e592. doi:10.1111/j.1467-789X.2011.00881.x
Dougkas A, Reynolds CK, Givens ID, Elwood PC, Minihane AM (2011) Associations between dairy consumption and body weight: a review of the evidence and underlying mechanisms. Nutr Res Rev 24(1):72–95. doi:10.1017/s095442241000034x
McGregor RA, Poppitt SD (2013) Milk protein for improved metabolic health: a review of the evidence. Nutr Metab (Lond) 10(1):46. doi:10.1186/1743-7075-10-46.
Martinez-Gonzalez MA, Sayon-Orea C, Ruiz-Canela M, de la Fuente C, Gea A, Bes-Rastrollo M (2014) Yogurt consumption, weight change and risk of overweight/obesity: The SUN cohort study. Nutr Metab Cardiovasc Dis. doi:10.1016/j.numecd.02014.00105.00015
McCarron DA, Morris CD, Henry HJ, Stanton JL (1984) Blood pressure and nutrient intake in the United States. Science 224(4656):1392–1398
Zemel MB, Shi H, Greer B, Dirienzo D, Zemel PC (2000) Regulation of adiposity by dietary calcium. FASEB J 14(9):1132–1138
Zemel MB, Thompson W, Milstead A, Morris K, Campbell P (2004) Calcium and dairy acceleration of weight and fat loss during energy restriction in obese adults. Obes Res 12(4):582–590. doi:10.1038/oby.2004.67
Zemel MB, Richards J, Mathis S, Milstead A, Gebhardt L, Silva E (2005) Dairy augmentation of total and central fat loss in obese subjects. Int J Obes 29(4):391–397. doi:10.1038/sj.ijo.0802880
Zemel MB, Richards J, Milstead A, Campbell P (2005) Effects of calcium and dairy on body composition and weight loss in African-American adults. Obes Res 13(7):1218–1225. doi:10.1038/oby.2005.144
Astrup A, Chaput JP, Gilbert JA, Lorenzen JK (2010) Dairy beverages and energy balance. Physiol Behav 100(1):67–75. doi:10.1016/j.physbeh.2010.01.039
Birge SJ Jr, Keutmann HT, Cuatrecasas P, Whedon GD (1967) Osteoporosis, intestinal lactase deficiency and low dietary calcium intake. N Engl J Med 276(8):445–448. doi:10.1056/nejm196702232760805
Finkenstedt G, Skrabal F, Gasser RW, Braunsteiner H (1986) Lactose absorption, milk consumption, and fasting blood glucose concentrations in women with idiopathic osteoporosis. Br Med J (Clin Res Ed) 292(6514):161–162
Wilt TJ, Shaukat A, Shamliyan T, Taylor BC, MacDonald R, Tacklind J, Rutks I, Schwarzenberg SJ, Kane RL, Levitt M (2010) Lactose intolerance and health. Evid Rep/Technol Assess 192:1–410
Savaiano DA, Boushey CJ, McCabe GP (2006) Lactose intolerance symptoms assessed by meta-analysis: a grain of truth that leads to exaggeration. J Nutr 136(4):1107–1113
Suchy FJ, Brannon PM, Carpenter TO, Fernandez JR, Gilsanz V, Gould JB, Hall K, Hui SL, Lupton J, Mennella J, Miller NJ, Osganian SK, Sellmeyer DE, Wolf MA (2010) NIH consensus development conference statement: lactose intolerance and health. NIH Consens State Sci Statements 27(2):1–27
McBean LD, Miller GD (1998) Allaying fears and fallacies about lactose intolerance. J Am Diet Assoc 98(6):671–676. doi:10.1016/s0002-8223(98)00152-7
Savaiano DA (2014) Lactose digestion from yogurt: mechanism and relevance. Am J Clin Nutr 99(5 Suppl):1251S–1255S. doi:10.3945/ajcn.113.073023
Dainese-Plichon R, Schneider S, Piche T, Hébuterne X (2014) Lactose malabsorption and intolerance in adult subjects [article in French]. Nutr Clin Métabol 28(1):46–51
Litwic A, Edwards MH, Dennison EM, Cooper C (2013) Epidemiology and burden of osteoarthritis. Br Med Bull 105:185–199. doi:10.1093/bmb/lds038
Dean E, Gormsen Hansen R (2012) Prescribing optimal nutrition and physical activity as “first-line” interventions for best practice management of chronic low-grade inflammation associated with osteoarthritis: evidence synthesis. Arthritis 2012:560634. doi:10.1155/2012/560634
Nestel PJ, Pally S, MacIntosh GL, Greeve MA, Middleton S, Jowett J, Meikle PJ (2012) Circulating inflammatory and atherogenic biomarkers are not increased following single meals of dairy foods. Eur J Clin Nutr 66:25–31
Gagliardi AC, Maranhao RC, de Sousa HP, Schaefer EJ, Santos RD (2010) Effects of margarines and butter consumption on lipid profiles, inflammation markers and lipid transfer to HDL particles in free-living subjects with the metabolic syndrome. Eur J Clin Nutr 64:1141–1149
Raff M, Tholstrup T, Basu S, Nonboe P, Sorensen MT, Straarup EM (2008) A diet rich in conjugated linoleic acid and butter increases lipid peroxidation but does not affect atherosclerotic, inflammatory, or diabetic risk markers in healthy young men. J Nutr 138:509–514
Panagiotakos DB, Pitsavos CH, Zampelas AD, Chrysohoou CA, Stefanadis CI (2010) Dairy products consumption is associated with decreased levels of inflammatory markers related to cardiovascular disease in apparently healthy adults: the ATTICA study. J Am Coll Nutr 29:357–364
Wang H, Steffen LM, Vessby B, Basu S, Steinberger J, Moran A, Jacobs DR, Hong CP, Sinaiko A (2011) Obesity modifies the relations between serum markers of dairy fats and inflammation and oxidative stress among adolescents. Obesity (Silver Spring, Md) 19:2404–2410
Labonte ME, Couture P, Richard C, Desroches S, Lamarche B (2013) Impact of dairy products on biomarkers of inflammation: a systematic review of randomized controlled nutritional intervention studies in overweight and obese adults. Am J Clin Nutr 97:706–717
Labonte ME, Cyr A, Abdullah MM, Lepine MC, Vohl MC, Jones P, Couture P, Lamarche B (2014) Dairy product consumption has no impact on biomarkers of inflammation among men and women with low-grade systemic inflammation. J Nutr 144:1760–1767
Lu B, Driban JB, Duryea J, McAlindon T, Lapane KL, Eaton CB (2014) Milk consumption and progression of medial tibiofemoral knee osteoarthritis: data from the osteoarthritis initiative. Arthritis Care Res 66(6):802–809. doi:10.1002/acr.22297
Li S, Micheletti R (2011) Role of diet in rheumatic disease. Rheum Dis Clin North Am 37(1):119–133. doi:10.1016/j.rdc.2010.11.006
Lahiri M, Morgan C, Symmons DP, Bruce IN (2012) Modifiable risk factors for RA: prevention, better than cure? Rheumatology (Oxford) 51(3):499–512. doi:10.1093/rheumatology/ker299
Gonzalez Cernadas L, Rodriguez-Romero B, Carballo-Costa L (2014) Importance of nutritional treatment in the inflammatory process of rheumatoid arthritis patients; a review. Nutr Hosp 29(2):237–245. doi:10.3305/nh.2014.29.2.7067
Stamp LK, James MJ, Cleland LG (2005) Diet and rheumatoid arthritis: a review of the literature. Semin Arthritis Rheum 35(2):77–94. doi:10.1016/j.semarthrit.2005.05.001
Smedslund G, Byfuglien MG, Olsen SU, Hagen KB (2010) Effectiveness and safety of dietary interventions for rheumatoid arthritis: a systematic review of randomized controlled trials. J Am Diet Assoc 110(5):727–735. doi:10.1016/j.jada.2010.02.010
Hagen KB, Byfuglien MG, Falzon L, Olsen SU, Smedslund G (2009) Dietary interventions for rheumatoid arthritis. Cochrane Database Syst Rev. doi:10.1002/14651858.CD006400.pub2
Lawrence GD (2013) Dietary fats and health: dietary recommendations in the context of scientific evidence. Adv Nutr 4(3):294–302. doi:10.3945/an.113.003657
Gossec L, Pavy S, Pham T, Constantin A, Poiraudeau S, Combe B, Flipo RM, Goupille P, Le Loët X, Mariette X, Puéchal X, Wendling D, Schaeverbeke T, Sibilia J, Tebib J, Cantagrel A, Dougados M (2006) Nonpharmacological treatments in early rheumatoid arthritis: clinical practice guidelines based on published evidence and expert opinion. Joint Bone Spine 73(4):396–402
Martin RH (1998) The role of nutrition and diet in rheumatoid arthritis. Proc Nutr Soc 57(2):231–234
WHO (2015) World Health Organization. Cardiovascular diseases (CVDs). Fact sheet N°317. Updated January 2015. http://www.who.int/mediacentre/factsheets/fs317/en/. Accessed 21 July 2015
Salehi-Abargouei A, Maghsoudi Z, Shirani F, Azadbakht L (2013) Effects of Dietary Approaches to Stop Hypertension (DASH)-style diet on fatal or nonfatal cardiovascular diseases–incidence: a systematic review and meta-analysis on observational prospective studies. Nutrition 29(4):611–618
Huth PJ, Park KM (2012) Influence of dairy product and milk fat consumption on cardiovascular disease risk: a review of the evidence. Adv Nutr 3(3):266–285
Benatar JR, Sidhu K, Stewart RA (2013) Effects of high and low fat dairy food on cardio-metabolic risk factors: a meta-analysis of randomized studies. PLoS One 8(10):e76480
Ralston RA, Lee JH, Truby H, Palermo CE, Walker KZ (2012) A systematic review and meta-analysis of elevated blood pressure and consumption of dairy foods. J Hum Hypertens 26(1):3–13
Soedamah-Muthu SS, Verberne LD, Ding EL, Engberink MF, Geleijnse JM (2012) Dairy consumption and incidence of hypertension: a dose-response meta-analysis of prospective cohort studies. Hypertension 60(5):1131–1137
Qin LQ, Xu JY, Han SF, Zhang ZL, Zhao YY, Szeto IM (2015) Dairy consumption and risk of cardiovascular disease: an updated meta-analysis of prospective cohort studies. Asia Pac J Clin Nutr 24(1):90–100
Soedamah-Muthu SS, Ding EL, Al-Delaimy WK, Hu FB, Engberink MF, Willett WC, Geleijnse JM (2011) Milk and dairy consumption and incidence of cardiovascular diseases and all-cause mortality: dose-response meta-analysis of prospective cohort studies. Am J Clin Nutr 93(1):158–171
Hu D, Huang J, Wang Y, Zhang D, Qu Y (2014) Dairy foods and risk of stroke: a meta-analysis of prospective cohort studies. Nutr Metab Cardiovasc Dis 24(5):460–469
Perk J, De Backer G, Gohlke H, Graham I, Reiner Z, Verschuren M, Albus C, Benlian P, Boysen G, Cifkova R, Deaton C, Ebrahim S, Fisher M, Germano G, Hobbs R, Hoes A, Karadeniz S, Mezzani A, Prescott E, Ryden L, Scherer M, Syvänne M, Scholte Op Reimer WJ, Vrints C, Wood D, Zamorano JL, Zannad F (2012) European Guidelines on cardiovascular disease prevention in clinical practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts). Eur Heart J 33(13):1635–1701
Eckel RH, Jakicic JM, Ard JD, de Jesus JM, Houston Miller N, Hubbard VS, Lee IM, Lichtenstein AH, Loria CM, Millen BE, Nonas CA, Sacks FM, Smith SC, Svetkey LP, Wadden TA, Yanovski SZ, Kendall KA, Morgan LC, Trisolini MG, Velasco G, Wnek J, Anderson JL, Halperin JL, Albert NM, Bozkurt B, Brindis RG, Curtis LH, DeMets D, Hochman JS, Kovacs RJ, Ohman EM, Pressler SJ, Sellke FW, Shen WK, Smith SC, Tomaselli GF (2014) 2013 AHA/ACC guideline on lifestyle management to reduce cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 129(25 (Suppl 2)):S76–S99
de Oliveira Otto MC, Mozaffarian D, Kromhout D, Bertoni AG, Sibley CT, Jacobs DR, Nettleton JA (2012) Dietary intake of saturated fat by food source and incident cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis. Am J Clin Nutr 96(2):397–404
Chowdhury R, Warnakula S, Kunutsor S, Crowe F, Ward HA, Johnson L, Franco OH, Butterworth AS, Forouhi NG, Thompson SG, Khaw KT, Mozaffarian D, Danesh J (2014) Di Angelantonio E (2014) Association of dietary, circulating, and supplement fatty acids with coronary risk: a systematic review and meta-analysis. Ann Intern Med 160(6):398–406
Bolland MJ, Avenell A, Baron JA, Grey A, MacLennan GS, Gamble GD, Reid IR (2010) Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: meta-analysis. BMJ 341:c3691. doi:10.1136/bmj.c3691
Kanis JA, Johansson H, Oden A, De Laet C, Johnell O, Eisman JA, Mc Closkey E, Mellstrom D, Pols H, Reeve J, Silman A, Tenenhouse A (2005) A meta-analysis of milk intake and fracture risk: low utility for case finding. Osteoporosis Int 16(7):799–804
Owusu W, Willett WC, Feskanich D, Ascherio A, Spiegelman D, Colditz GA (1997) Calcium intake and the incidence of forearm and hip fractures among men. J Nutr 127(9):1782–1787
Cumming RG, Cummings SR, Nevitt MC, Scott J, Ensrud KE, Vogt TM, Fox K (1997) Calcium intake and fracture risk: results from the study of osteoporotic fractures. Am J Epidemiol 145(10):926–934
Meyer HE, Pedersen JI, Løken EB, Tverdal A (1997) Dietary factors and the incidence of hip fracture in middle-aged Norwegians. A prospective study. Am J Epidemiol 145(2):117–123
Fujiwara S, Kasagi F, Yamada M, Kodama K (1997) Risk factors for hip fracture in a Japanese cohort. J Bone Miner Res 12(7):998–1004
Feskanich D, Bischoff-Ferrari HA, Frazier AL, Willett WC (2014) Milk consumption during teenage years and risk of hip fractures in older adults. JAMA pediatrics 168(1):54–60. doi:10.1001/jamapediatrics.2013.3821
Feart C, Lorrain S, Ginder Coupez V, Samieri C, Letenneur L, Paineau D, Barberger-Gateau P (2013) Adherence to a Mediterranean diet and risk of fractures in French older persons. Osteoporos Int 24(12):3031–3041
Benetou V, Orfanos P, Zylis D, Sieri S, Contiero P, Tumino R, Giurdanella MC, Peeters PH, Linseisen J, Nieters A, Boeing H, Weikert C, Pettersson U, Johansson I, Bueno-de-Mesquita HB, Dorronsoro M, Boffetta P, Trichopoulou A (2011) Diet and hip fractures among elderly Europeans in the EPIC cohort. Eur J Clin Nutr 65(1):132–139
Díez-Pérez A, González-Macías J, Marín F, Abizanda M, Alvarez R, Gimeno A, Pegenaute E, Vila J (2007) Prediction of absolute risk of non-spinal fractures using clinical risk factors and heel quantitative ultrasound. Osteoporos Int 18(5):629–639
Roy DK, O’Neill TW, Finn JD, Lunt M, Silman AJ, Felsenberg D, Armbrecht G, Banzer D, Benevolenskaya LI, Bhalla A, Bruges Armas J, Cannata JB, Cooper C, Dequeker J, Diaz MN, Eastell R, Yershova OB, Felsch B, Gowin W, Havelka S, Hoszowski K, Ismail AA, Jajic I, Janott I, Johnell O, Kanis JA, Kragl G, Lopez Vaz A, Lorenc R, Lyritis G, Masaryk P, Matthis C, Miazgowski T, Gennari C, Pols HA, Poor G, Raspe HH, Reid DM, Reisinger W, Scheidt-Nave C, Stepan JJ, Todd CJ, Weber K, Woolf AD, Reeve J (2003) Determinants of incident vertebral fracture in men and women: results from the European Prospective Osteoporosis Study (EPOS). Osteoporos Int 14(1):19–26. doi:10.1007/s00198-002-1317-8
Looker AC, Harris TB, Madans JH, Sempos CT (1993) Dietary calcium and hip fracture risk: the NHANES I Epidemiologic Follow-Up Study. Osteoporos Int 3(4):177–184