[fr] Depuis des lustres, le mélanome cutané sporadique, qu’il soit à croissance lente ou rapide, est identifié par un ensemble de critères histopathologiques bien définis. Cette démarche diagnostique est largement reconnue, et elle apporte une estimation approximative de l’évolution probable de cancer. Des évaluations complémentaires cherchent à préciser le pronostic évolutif du mélanome. Dans ce cadre, les analyses fractales et spectrales tentent de mieux saisir les particularités évolutives individuelles de chaque tumeur. C’est, d’une part, l’étendue du compartiment germinatif tumoral, et d’autre part, le réseau microvasculaire péritumoral qui sont ainsi explorés et qui pourraient à l’avenir préciser le pronostic évolutif du mélanome cutané. La possibilité d’une éventuelle régression tumorale et une réaction immunitaire efficace pourrait mieux être identifiée. [en] For aeons, cutaneous sporadic melanoma, exhibiting either a slow or rapid growth rate, is identified using a set of well defined histopathological criteria. Such diagnostic step is greatly appreciated, and it brings a rough estimate of the probable evolution of the cancer. Some additional assessments try to improve the progressive prognosis of cutaneous melanoma. In this scope, fractals and spectral analyses expect to better perceive the individual progressive characteristics of each tumor. The extent in the tumoral germinative compartment and the peritumoral microvascular network are explored and should in a near future make clear the progressive potential of cutaneous melanoma. The possible tumoral regression and the immune reaction should be better perceived.
Disciplines :
Dermatology
Author, co-author :
Pierard, Gérald ; Université de Liège > Département des sciences cliniques > Département des sciences cliniques
Pierard-Franchimont, Claudine ; Université de Liège > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques
Language :
French
Title :
Le mélanome cutané sporadique au-delà de sa classification normative. Plaidoyer prenant en compte son particularisme évolutif
Publication date :
2015
Journal title :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Publisher :
Université de Liège. Revue Médicale de Liège, Liège, Belgium
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