Effects of thirty elements on bone metabolism

[en] The human skeleton, made of 206 bones, plays vital roles including supporting the body, protecting organs, enabling movement, and storing minerals. Bones are made of organic structures, intimately connected with an inorganic matrix produced by bone cells. Many elements are ubiquitous in our environment, and many impact bone metabolism. Most elements have antagonistic actions depending on concentration. Indeed, some elements are essential, others are deleterious, and many can be both. Several pathways mediate effects of element deficiencies or excesses on bone metabolism. This paper aims to identify all elements that impact bone health and explore the mechanisms by which they act. To date, this is the first time that the effects of thirty minerals on bone metabolism have been summarized.

Disciplines :

Endocrinology, metabolism & nutrition

Author, co-author :

DERMIENCE, Michael ; Université de Liège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Analyse, qual. et risques - Labo. de Chimie analytique

Lognay, Georges ; Université de Liège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Analyse, qual. et risques - Labo. de Chimie analytique

Mathieu, Françoise; Kashin–Beck Disease Fund asbl-vzw

Goyens, Phillippe; Free Universities of Brussels > Department and Laboratory of Pediatric

Language :

English

Title :

Effects of thirty elements on bone metabolism

Publication date :

2015

Journal title :

Journal of Trace Elements in Medicine and Biology

ISSN :

0946-672X

eISSN :

1878-3252

Publisher :

Gustav Fischer Verlag, Stuttgart, Germany

Issue :

Pages :

86-106

Peer reviewed :

Peer Reviewed verified by ORBi

Additional URL :

http://authors.elsevier.com/a/1RJsm,LXbjlMNy

Available on ORBi :

since 06 July 2015

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