Method and device for synthesizing labeled compounds

A method for synthesizing compds. labeled with any isotopic element is disclosed. The method comprises the steps of prepg. the labeling agent, labeling a precursor in the form of a protected substrate, pre-​purifying and deprotecting same, and forming a final soln. of the resulting compd. The deprotection step, in which the labeled precursor is converted into a labeled compd., is performed directly on a solid medium in a column or a cartridge. A device for synthesizing the labeled compd. according to said method is also disclosed. Thus, 2-​[18F]​fluoro-​2-​deoxy-​D-​glucose and 1,​3,​4,​6-​tetra-​O-​acetyl-​2-​trifluoromethanesulfonyl-​β-​D-​mannopyranose were prepd.