Reference : Method and device for synthesizing labeled compounds
Patent : Patent
Physical, chemical, mathematical & earth Sciences : Chemistry
http://hdl.handle.net/2268/183550
Method and device for synthesizing labeled compounds
English
[fr] Procédé et dispositif de synthèse de composés marqués
Lemaire, Christian mailto [Université de Liège > > Centre de recherches du cyclotron >]
Damhaut, Philippe []
Monclus, Michel [Université Libre de Bruxelles - ULB > > > >]
Van Namen, John [Université Libre de Bruxelles - ULB > > > >]
Mulleneers, Eric [Université Libre de Bruxelles - ULB > > > >]
Morelle, Jean-Luc [SA Coincidence > > > >]
Luxen, André mailto [Université de Liège > Département de chimie (sciences) > Laboratoire de chimie organique de synthèse >]
Lauricella, Beniamino mailto [Université de Liège > > Centre de recherches du cyclotron >]
13-Nov-1997
1997-04-30
OEB
WO 97/42203
9600388 (02.05.96)
B
Belgique
Université de Liège, Coincidence SA, Université Libre de Bruxelles
C0H7 5/02, C07B 59/00
C07H005-02 C07B059-00
JP, US, brevet européen (AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE)
AT, BE, CH, DE, DK, ES, FI, FR, GB, GR, IE, IT, LU, MC, NL, PT, SE
[en] A method for synthesizing compds. labeled with any isotopic element is disclosed. The method comprises the steps of prepg. the labeling agent, labeling a precursor in the form of a protected substrate, pre-​purifying and deprotecting same, and forming a final soln. of the resulting compd. The deprotection step, in which the labeled precursor is converted into a labeled compd., is performed directly on a solid medium in a column or a cartridge. A device for synthesizing the labeled compd. according to said method is also disclosed. Thus, 2-​[18F]​fluoro-​2-​deoxy-​D-​glucose and 1,​3,​4,​6-​tetra-​O-​acetyl-​2-​trifluoromethanesulfonyl-​β-​D-​mannopyranose were prepd.
http://hdl.handle.net/2268/183550

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