Reference : Biotechnological uses of RNAi in plants: Risk assessment considerations
Scientific journals : Other
Life sciences : Phytobiology (plant sciences, forestry, mycology...)
Life sciences : Biotechnology
http://hdl.handle.net/2268/182044
Biotechnological uses of RNAi in plants: Risk assessment considerations
English
Casacuberta, J. M. [Center for Research in Agricultural Genomics, Consejo Superior de Investigaciones Científicas-Institut de Recerca i Tecnologia, Agroalimentàries-Universitat Autònoma de Barcelona-Universitat de Barcelona, Campus Universitat Autònoma de Barcelona, Bellaterra - Cerdanyola del Vallès, Barcelona, Spain]
Devos, Y. [European Food Safety Authority, Via Carlo Magno 1/A, Parma, Italy]
du Jardin, Patrick mailto [Université de Liège > Agronomie, Bio-ingénierie et Chimie (AgroBioChem) > Biologie végétale >]
Ramon, M. [European Food Safety Authority, Via Carlo Magno 1/A, Parma, Italy]
Vaucheret, H. [INRA, Institut Jean-Pierre Bourgin, Saclay Plant Sciences, Versailles, France, AgroParisTech, Institut Jean-Pierre Bourgin, Saclay Plant Sciences, Versailles, France]
Nogué, F. [INRA, Institut Jean-Pierre Bourgin, Saclay Plant Sciences, Versailles, France, AgroParisTech, Institut Jean-Pierre Bourgin, Saclay Plant Sciences, Versailles, France]
2015
Trends in Biotechnology
Elsevier
33
3
145-147
Yes (verified by ORBi)
International
0167-7799
[en] Food/feed safety ; Gene silencing ; Genetically modified organism (GMO) ; Nontarget organism (NTO) ; Off-target gene ; Plant breeding ; Note ; RNA interference
[en] RNAi offers opportunities to generate new traits in genetically modified (GM) plants. Instead of expressing novel proteins, RNAi-based GM plants reduce target gene expression. Silencing of off-target genes may trigger unintended effects, and identifying these genes would facilitate risk assessment. However, using bioinformatics alone is not reliable, due to the lack of genomic data and insufficient knowledge of mechanisms governing mRNA-small (s)RNA interactions. © 2014 Elsevier Ltd.
http://hdl.handle.net/2268/182044
10.1016/j.tibtech.2014.12.003

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Open access
Casacuberta2015.pdfPublisher postprint212.75 kBView/Open

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.