[en] In one geographical area, 14 high-risk human papillomavirus types in cervical intraepithelial neoplasia (CIN2/3; n=139) and cervical squamous cell carcinoma (SCC; n=84) were analysed. HPV18 was more prevalent in SCC than CIN2/3 (OR 9.8; 95% confidence interval: 2.5-39). Other high-risk types prevalences corresponded in CIN2/3 and SCC. Evaluations using CIN2/3 as a measure of efficiency underestimate the contribution of HPV18 to SCC.
Disciplines :
Genetics & genetic processes
Author, co-author :
BULK, Saskia ; Centre Hospitalier Universitaire de Liège - CHU > Génétique
Berkhof, J.
Rozendaal, L.
Fransen Daalmeijer, N. C.
Gok, M.
de Schipper, F. A.
van Kemenade, F. J.
Snijders, P. J. F.
Meijer, C. J. L. M.
Language :
English
Title :
The contribution of HPV18 to cervical cancer is underestimated using high-grade CIN as a measure of screening efficiency.
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