A novel, possibly functional, single nucleotide polymorphism in the coding region of the thrombin-activatable fibrinolysis inhibitor (TAFI) gene is also associated with TAFI levels.
BULK, Saskia ; Centre Hospitalier Universitaire de Liège - CHU > Génétique
Schneider, M.
Boffa, M.
Koschinsky, M.
van Tilburg, N. H.
Nesheim, M. E.
Bertina, R. M.
Gomez Garcia, E. B.
Language :
English
Title :
A novel, possibly functional, single nucleotide polymorphism in the coding region of the thrombin-activatable fibrinolysis inhibitor (TAFI) gene is also associated with TAFI levels.
Publication date :
2001
Journal title :
Blood
ISSN :
0006-4971
eISSN :
1528-0020
Publisher :
American Society of Hematology, Washington, United States - District of Columbia
Henry M, Aubert H, Morange PE, et al. Identification of polymorphisms in the promoter and the 3′ region of the TAFI gene: evidence that plasma TAFI antigen levels are strongly genetically controlled. Blood. 2001;97:2053-2058.
Zhao L, Morser J, Bajzar L, Nesheim M, Nagashima M. Identification and characterization of two thrombin-activatable fibrinolysis inhibitor isoforms. Thromb Haemost. 1998;80:949-955.
Franco RF, Fagundes MG, Meijers JCM, et al. Identification of polymorphisms in the TAFI gene promoter; relationship with plasma TAFI levels and risk of venous thrombosis [abstract]. Blood. 2000;96:565a.
Crainich P, Tang Z, Macy EM, et al. A polymorphism at position -438 in the promoter region of thrombin-activatable fibrinolysis inhibitor (TAFI) is strongly associated with plasma antigen levels in healthy older men and women [abstract]. Circulation. 2000;102(suppl II):866.
Schneider MS, Boffa MB, Rahman MN, et al. A variant of human TAFI exhibits increased thermal stability and increased antifibrinolytic potential [abstract]. Thromb Haemost (CD-ROM). July 2001 (suppl). Abstract OC1756.
van Tilburg NH, Rosendaal FR, Bertina RM. Thrombin activatable fibrinolysis inhibitor and the risk for deep vein thrombosis. Blood. 2000;95:2855-2859.
Marx PF, Bouma BN, Meijers JCM. Plasmin mediated activation and inactivation of thrombin-activatable fibrinolysis inhibitor [abstract]. Blood. 2000;96:44a.