Article (Scientific journals)
Trabecular bone score (TBS) as a new complementary approach for osteoporosis evaluation in clinical practice.
Harvey, N. C.; Gluer, C. C.; Binkley, N. et al.
2015In BONE, 78, p. 216-224
Peer Reviewed verified by ORBi
 

Files


Full Text
Trabecular bone score (TBS) as a new complementary approach for osteoporosis evaluation in clinical practice.pdf
Publisher postprint (354.74 kB)
Request a copy

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
FRAX; bone mineral density; epidemiology; fragility fracture; osteoporosis; trabecular bone score (TBS)
Abstract :
[en] Trabecular bone score (TBS) is a recently-developed analytical tool that performs novel grey-level texture measurements on lumbar spine dual X-ray absorptiometry (DXA) images, and thereby captures information relating to trabecular microarchitecture. In order for TBS to usefully add to bone mineral density (BMD) and clinical risk factors in osteoporosis risk stratification, it must be independently associated with fracture risk, readily obtainable, and ideally, present a risk which is amenable to osteoporosis treatment. This paper summarizes a review of the scientific literature performed by a Working Group of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis. Low TBS is consistently associated with an increase in both prevalent and incident fractures that is partly independent of both clinical risk factors and areal BMD (aBMD) at the lumbar spine and proximal femur. More recently, TBS has been shown to have predictive value for fracture independent of fracture probabilities using the FRAX(R) algorithm. Although TBS changes with osteoporosis treatment, the magnitude is less than that of aBMD of the spine, and it is not clear how change in TBS relates to fracture risk reduction. TBS may also have a role in the assessment of fracture risk in some causes of secondary osteoporosis (e.g. diabetes, hyperparathyroidism and glucocorticoid-induced osteoporosis). In conclusion, there is a role for TBS in fracture risk assessment in combination with both aBMD and FRAX.
Disciplines :
General & internal medicine
Author, co-author :
Harvey, N. C.
Gluer, C. C.
Binkley, N.
McCloskey, E. V.
Brandi, M.-L.
Cooper, C.
Kendler, D.
Lamy, O.
Laslop, A.
Camargos, B. M.
Reginster, Jean-Yves  ;  Université de Liège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Rizzoli, R.
Kanis, J. A.
More authors (3 more) Less
Language :
English
Title :
Trabecular bone score (TBS) as a new complementary approach for osteoporosis evaluation in clinical practice.
Publication date :
2015
Journal title :
BONE
ISSN :
8756-3282
eISSN :
1873-2763
Publisher :
Elsevier, Netherlands
Volume :
78
Pages :
216-224
Peer reviewed :
Peer Reviewed verified by ORBi
Commentary :
Copyright (c) 2015. Published by Elsevier Inc.
Available on ORBi :
since 22 May 2015

Statistics


Number of views
71 (12 by ULiège)
Number of downloads
2 (2 by ULiège)

Scopus citations®
 
333
Scopus citations®
without self-citations
299
OpenCitations
 
285

Bibliography


Similar publications



Contact ORBi