Article (Scientific journals)
Prognostic indices for mortality of hospitalized children in central Africa.
Dramaix, M.; Brasseur, D.; Donnen, P. et al.
1996In American Journal of Epidemiology, 143 (12), p. 1235-43
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Keywords :
Anthropometry; Body Height; Body Weight; Child; Child, Hospitalized; Child, Preschool; Democratic Republic of the Congo/epidemiology; Edema/diagnosis; Follow-Up Studies; Hospital Mortality; Humans; Infant; Prealbumin/analysis; Predictive Value of Tests; Prognosis; Protein-Energy Malnutrition/diagnosis; ROC Curve; Risk Factors; Sensitivity and Specificity; Serum Albumin/analysis; Africa; Africa South Of The Sahara; Age Factors; Child Mortality; Delivery Of Health Care; Demographic Factors; Developing Countries; Diseases; French Speaking Africa; Health; Health Facilities; Hospitals; Malnutrition; Measurement; Middle Africa; Mortality; Nutrition Disorders; Population; Population At Risk; Population Characteristics; Population Dynamics; Research Methodology; Research Report; Studies; Youth; Zaire
Abstract :
[en] A hospital-based follow-up study was conducted between 1986 and 1988 at Lwiro (South Kivu Province, Zaire). Of 1,129 children in the study, three of four were severely malnourished, and 17.4% died. This study analyzes the mortality in hospital; its objectives are to evaluate the prognostic power of edema and anthropometric and biologic indicators and to seek indices that perform better. Receiver operating characteristic curves were established for each parameter under study and for each index constructed. Areas under receiver operating characteristic curves were highest for biologic indicators, and simple indices, obtained by counting the number of risk factors present, performed best. In the absence of biologic parameters, the authors suggest classifying children as at risk of dying when they present with edema and/or with arm circumference of less than 115 mm. When biologic measurements are possible, in addition to edema and arm circumference, the authors suggest taking serum albumin and transthyretin into account. For serum albumin and transthyretin, mortality risk is defined in terms of values of less than 16 g/liter and 6.5 mg/dl, respectively. Children will be classified as at risk of dying when they present with at least two of the four risk factors. The resulting diagnostic test has a high sensitivity (91.2%) and positive and negative predictive values of 40.8% and 97.9%, respectively.
Disciplines :
General & internal medicine
Author, co-author :
Dramaix, M.
Brasseur, D.
Donnen, P.
Bawhere, P.
Porignon, Denis  ;  Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique : aspects spécifiques
Tonglet, R.
Hennart, P.
Language :
English
Title :
Prognostic indices for mortality of hospitalized children in central Africa.
Publication date :
1996
Journal title :
American Journal of Epidemiology
ISSN :
0002-9262
eISSN :
1476-6256
Publisher :
Oxford University Press, United Kingdom
Volume :
143
Issue :
12
Pages :
1235-43
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
PIP: TJ: AMERICAN JOURNAL OF EPIDEMIOLOGY.
Available on ORBi :
since 28 January 2015

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