Article (Scientific journals)
A critical role of plastidial glycolytic glyceraldehyde-3-phosphate dehydrogenase in the control of plant metabolism and development
Muñoz-Bertomeu, Jesús; Cascales - Miñana, Borja; Alaiz, Manuel et al.
2010In Plant Signaling and Behavior, 5 (1), p. 67-69
Peer Reviewed verified by ORBi
 

Files


Full Text
A critical role of plastidial glycolytic Glyceraldehyde-3-Phosphate Dehydrogenase in the control of plant metabolism and development.pdf
Publisher postprint (233.82 kB)
Request a copy

All documents in ORBi are protected by a user license.

Send to



Details



Keywords :
Arabidopsis; GAPDH; Glycolysis; Plastid; Serine biosynthesis; Glyceraldehyde-3-Phosphate Dehydrogenases; Phosphorylation; Plant Roots; Plastids; Serine
Abstract :
[en] Glycolysis is a central metabolic pathway that provides energy and generates precursors for the synthesis of primary metabolites such as amino acids and fatty acids.1-3 In plants, glycolysis occurs in the cytosol and plastids, which complicates the understanding of this essential process.1 As a result, the contribution of each glycolytic pathway to the specific primary metabolite production and the degree of integration of both pathways is still unresolved. The glycolytic glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the conversion of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate. Both cytosolic (GAPCs) and plastidial (GAPCps) GAPDH activities have been described biochemically. But, up to now, little attention had been paid to GAPCps, probably because they have been considered as "minor isoforms" that catalyze a reversible reaction in plastids where it has been assumed that key glycolytic intermediates are in equilibrium with the cytosol. In the associated study,4 we have elucidated the crucial role of Arabidopsis GAPCps in the control of primary metabolism in plants. GAPCps deficiency affects amino acid and sugar metabolism and impairs plant development. Specifically, GAPCp deficiency affects the serine supply to roots, provoking a drastic phenotype of arrested root development. Also, we show that the phosphorylated serine biosynthesis pathway is critical to supply serine to non-photosynthetic organs such as roots. These studies provide new insights of the contribution of plastidial glycolysis to plant metabolism and evidence the complex interactions existing between metabolism and development. © 2010 Landes Bioscience.
Disciplines :
Phytobiology (plant sciences, forestry, mycology...)
Author, co-author :
Muñoz-Bertomeu, Jesús;  Departament de Biologia Vegetal, Facultat de Farmàcia, Universitat de València, Burjassot, Valencia, Spain
Cascales - Miñana, Borja ;  Departament de Biologia Vegetal, Facultat de Farmácia, Universitat de València, 46100 Burjassot, Valencia, Spain
Alaiz, Manuel;  Departamento de Fisiología y Tecnología de Productos Vegetales, Instituto de la Grasa, Consejo Superior de Investigaciones Científicas, Sevilla, Spain
Segura, Juan;  Departament de Biologia Vegetal, Facultat de Farmàcia, Universitat de València, Burjassot, Valencia, Spain
Ros, Roc;  Departament de Biologia Vegetal, Facultat de Farmàcia, Universitat de València, Burjassot, Valencia, Spain
Language :
English
Title :
A critical role of plastidial glycolytic glyceraldehyde-3-phosphate dehydrogenase in the control of plant metabolism and development
Publication date :
2010
Journal title :
Plant Signaling and Behavior
ISSN :
1559-2316
eISSN :
1559-2324
Publisher :
Landes Bioscience, United States
Volume :
5
Issue :
1
Pages :
67-69
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 08 January 2015

Statistics


Number of views
17 (1 by ULiège)
Number of downloads
0 (0 by ULiège)

Scopus citations®
 
33
Scopus citations®
without self-citations
28
OpenCitations
 
30

Bibliography


Similar publications



Contact ORBi