Article (Scientific journals)
Prevalence of sarcopenia: the impact of different diagnostic cut-off limits.
Beaudart, Charlotte; Reginster, Jean-Yves; Slomian, Justine et al.
2014In Journal of Musculoskeletal and Neuronal Interactions, 14 (4), p. 425-31
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Keywords :
Sarcopenia; Prevalence; EWGSOP; Cut-off; Diagnosis
Abstract :
[en] INTRODUCTION: In the definition of the European Working Group on Sarcopenia in Older People (EWGSOP), different cut-off limits are proposed for appendicular lean mass, muscle strength and gait speed. Therefore we aimed to examine the variation in prevalence of sarcopenia obtained with these cut-off limits. MATERIALS AND METHODS: Subjects aged 65 years and older were recruited in an outpatient clinic in Belgium and screened for sarcopenia using the EWGSOP definition. Appendicular lean mass was measured by Dual Energy X-Ray Absorptiometry, muscle strength by a hydraulic handgrip dynamometer and gait speed was measured on a 4-meter distance. Two different cut-off points proposed by the EWGSOP were examined for each variable and 8 diagnostic methods were thereby established. RESULTS: 400 subjects were recruited for this study. Prevalence of sarcopenia varied from 9.25% to 18% depending on the cut-offs applied. When stratified by sex, it seems that the variation in prevalence of sarcopenia was mainly attributable to women. This prevalence ranged from 6.58% to 20.2% for women and only from 13.4% to 14.7% for men. CONCLUSION: Prevalence of sarcopenia varies widely depending on the EWGSOP cut-off points applied for women. This may limit clinical researches and development of therapeutic strategies in the field of sarcopenia.
Disciplines :
General & internal medicine
Author, co-author :
Beaudart, Charlotte ;  Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Reginster, Jean-Yves  ;  Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Slomian, Justine ;  Université de Liège - ULiège > Département des sciences de la santé publique > Epidémiologie clinique
Buckinx, Fanny  ;  Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Locquet, Médéa ;  Université de Liège - ULiège > Département des sciences de la santé publique > Epidémiologie clinique
Bruyère, Olivier  ;  Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Language :
English
Title :
Prevalence of sarcopenia: the impact of different diagnostic cut-off limits.
Publication date :
2014
Journal title :
Journal of Musculoskeletal and Neuronal Interactions
eISSN :
1108-7161
Publisher :
Hylonome Publications, Kifissia, Greece
Volume :
14
Issue :
4
Pages :
425-31
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 05 January 2015

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