[en] 2D-DIGE analysis coupled with mass spectrometry is a global, without a priori, comparative proteomic approach particularly suited to identify and quantify enzymes isoforms and structural proteins, thus making it an efficient tool for the characterization of the changes in cell phenotypes that occur in physiological and pathological conditions. In this data article in support of the research article entitled “Metabolic reprogramming in transformed mouse cortical astrocytes: a proteomic study” [1] we illustrate the changes in protein profile that occur during the metabolic reprogramming undergone by cultured mouse astrocytes in a model of in-vitro cancerous transformation [2].
Disciplines :
Biochemistry, biophysics & molecular biology
Author, co-author :
Bentaib, Azeddine; Université de Liège - ULiège > GIGA-Neuroscience
De Tullio, Pascal ; Université de Liège - ULiège > Département de pharmacie > Chimie pharmaceutique
Chneiweiss, Hervé; Université Pierre et Marie Currie - Paris 6 > Glial Plasticity and Cerebral Tumors > UMR8246 CNRS/U1130 Inserm/UMCR18
Hermans, Emmanuel; Université Catholique de Louvain - UCL > Institute of Neurosciences > Group of Neuropharmacology
Junier, Marie-Pierre; Université Pierre et Marie Currie - Paris 6 > Glial Plasticity and Cerebral Tumors > UMR8246 CNRS/U1130 Inserm/UMCR18
Leprince, Pierre ; Université de Liège - ULiège > GIGA - Neurosciences
Language :
English
Title :
Data in support of metabolic reprogramming in transformed mouse cortical astrocytes: A proteomic study
Bentaib A., de Tullio P., Chneiweiss H., Hermans E., Junier M.P., Leprince P. Metabolic reprogramming in transformed mouse cortical astrocytes: a proteomic study. J. Proteomics 2015, 113:292-314.
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