Article (Scientific journals)
Self-assembly of three bacterially-derived bioactive lipopeptides
Hamley, I.W.; Dehsorkhi, A.; Jauregi, P. et al.
2013In Soft Matter
Peer Reviewed verified by ORBi
 

Files


Full Text
Art 88 (2013).pdf
Publisher postprint (427.47 kB)
Download

All documents in ORBi are protected by a user license.

Send to



Details



Abstract :
[en] The self-assembly in aqueous solution of three lipopeptides obtained from Bacillus subtilis has been investigated. The lipopeptides surfactin, plipastatin and mycosubtilin contain distinct cyclic peptide headgroups as well as differences in alkyl chain length, branching and chain length distribution. Cryogenic transmission electron microscopy and X-ray scattering reveal that surfactin and plipastatin aggregate into 2 nm-radius spherical micelles, whereas in complete contrast mycosubtilin self-assembles into extended nanotapes based on bilayer ordering of the lipopeptides. Circular dichroism and FTIR spectroscopy indicate the presence of turn structures in the cyclic peptide headgroup. The unexpected distinct mode of self-assembly of mycosubtilin compared to the other two lipopeptides is ascribed to differences in the surfactant packing parameter. This in turn is due to specific features of the conformation of the peptide headgroup and alkyl chain branching.
Disciplines :
Microbiology
Author, co-author :
Hamley, I.W.
Dehsorkhi, A.
Jauregi, P.
Seitsonen, J.
Ruokolainen, J.
Coutte, F.
Chataigné, G.
Jacques, Philippe ;  Université de Liège - ULiège > Chimie et bio-industries > Bio-industries
Language :
English
Title :
Self-assembly of three bacterially-derived bioactive lipopeptides
Publication date :
August 2013
Journal title :
Soft Matter
ISSN :
1744-683X
eISSN :
1744-6848
Publisher :
Royal Society of Chemistry, Cambridge, United Kingdom
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 04 November 2014

Statistics


Number of views
119 (7 by ULiège)
Number of downloads
268 (3 by ULiège)

Scopus citations®
 
48
Scopus citations®
without self-citations
26
OpenCitations
 
40

Bibliography


Similar publications



Contact ORBi