Thermometer ions; Ion spectroscopy; Mass Spectrometry
Abstract :
[en] The dissociation of benzylpyridinium “thermometer” ions is widely used
to calibrate the internal energy of ions produced in mass spectrometry. The
fragmentation mechanism is usually believed to yield a benzylium cation, although
recent studies suggest the possibility of a rearrangement leading to the tropylium isomer,
which would compromise the accuracy of energy calibrations. In this study, we used
IRMPD spectroscopy to probe the dissociation pathways of the p-(tert-butyl)-
benzylpyridinium ion. Our results show that the formation of both benzylium and
tropylium products is feasible depending on the activation regime and on the reaction
time scale. Varying the trapping delays in the hexapole gives insight into a rearrangement
mechanism occurring through consecutive reactions with an isomerization from
benzylium to tropylium. Our work provides experimental validations for the established
calibration procedure and highlights the adequacy of IRMPD spectroscopy to
qualitatively resolve gas-phase rearrangement kinetics.
Research center :
Giga-Systems Biology and Chemical Biology - ULiège
Disciplines :
Chemistry
Author, co-author :
Morsa, Denis ; Université de Liège - ULiège > Département de chimie (sciences) > Laboratoire de spectrométrie de masse (L.S.M.)
Gabelica, Valérie ; Université de Liège - ULiège > Département de chimie (sciences) > Laboratoire de spectrométrie de masse (L.S.M.)
Rosu, Frédéric; Université de Liège - ULiège > Département de Chimie (Sciences) > Laboratoire de spectrométrie de masse (LSM)
Oomens, Jos; Radboud Universiteit Nijmegen > Institute for Molecules and Materials > FELIX Laboratory,
De Pauw, Edwin ; Université de Liège - ULiège > Département de chimie (sciences) > Laboratoire de spectrométrie de masse (L.S.M.)
Language :
English
Title :
Dissociation Pathways of Benzylpyridinium “Thermometer” Ions Depend on the Activation Regime: An IRMPD Spectroscopy Study
Publication date :
October 2014
Journal title :
Journal of Physical Chemistry Letters
eISSN :
1948-7185
Publisher :
American Chemical Society, Washington, United States - District of Columbia
FP7 - 226716 - ELISA - European Light Sources Activities - Synchrotrons and Free Electron Lasers
Funders :
F.R.S.-FNRS - Fonds de la Recherche Scientifique [BE] FRIA - Fonds pour la Formation à la Recherche dans l'Industrie et dans l'Agriculture [BE] CE - Commission Européenne [BE]
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