[en] INTRODUCTION: Cardiopathies are the world's leading cause of mortality and morbidity. Although rare, cardiovascular accidents can occur during intense and infrequent sporting activity, particularly among those who are unaware of their heart condition. The development of cardiospecific biochemical markers has led to a reconsideration of the role of biology in the diagnosis of cardiovascular illnesses. The aim of this study therefore was, through the use of cardiac biomarker assays, to highlight the impact of sustained physical effort in the form of intense and prolonged concentric isokinetic exercise and to research potential cardiovascular risks. MATERIALS AND METHODS: Eighteen subjects participated in a maximal concentric isokinetic exercise involving 30 knee flexion-extensions for each leg. Five blood tests were taken to study the kinetics of the cardiac biomarkers. Haemodynamic parameters were measured continuously using a Portapres, and respiratory parameters were measured using a Sensormedics Vmax 29C. RESULTS: The results showed significant increases in the creatine kinase, myoglobin, homocysteine and haemoglobin cardiac markers. Evolutionary trends were also observed for the following biomarkers: NT-proBNP, myeloperoxydase and C-reactive protein. All the physiological parameters measured presented statistically significant changes. CONCLUSION: Isokinetic effort leads to the release of cardiac markers in the blood, but these do not exceed the reference values in healthy subjects. Maximal concentric isokinetic exercise does not, therefore, lead to an increased risk of cardiovascular pathologies.
Disciplines :
Orthopedics, rehabilitation & sports medicine Laboratory medicine & medical technology
Author, co-author :
LE GOFF, Caroline ; Centre Hospitalier Universitaire de Liège - CHU > Chimie médicale
Kaux, Jean-François ; Université de Liège - ULiège > Département des sciences de la motricité > Département des sciences de la motricité
Couffignal, Vincent
Coubard, Romain
Mélon, Pierre
Cavalier, Etienne ; Université de Liège - ULiège > Département de pharmacie > Chimie médicale
Croisier, Jean-Louis ; Université de Liège - ULiège > Département des sciences de la motricité > Kinésithérapie générale et réadaptation
Language :
English
Title :
Identification of cardiac repercussions after intense and prolonged concentric isokinetic exercise in young sedentary people
Publication date :
September 2015
Journal title :
Clinical Physiology and Functional Imaging
ISSN :
1475-0961
eISSN :
1475-097X
Publisher :
Wiley, Oxford, United Kingdom
Volume :
35
Issue :
5
Pages :
368-375
Peer reviewed :
Peer Reviewed verified by ORBi
Commentary :
(c) 2014 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.
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