Article (Scientific journals)
Echocardiographic reference ranges for normal cardiac chamber size: results from the NORRE study.
Kou, Seisyou; Caballero, Luis; DULGHERU, Raluca Elena et al.
2014In European Heart Journal. Cardiovascular Imaging, 15 (6), p. 680-690
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Keywords :
Chamber size and function; Reference values; Two-dimensional echocardiography
Abstract :
[en] AIMS: Availability of normative reference values for cardiac chamber quantitation is a prerequisite for accurate clinical application of echocardiography. In this study, we report normal reference ranges for cardiac chambers size obtained in a large group of healthy volunteers accounting for gender and age. Echocardiographic data were acquired using state-of-the-art cardiac ultrasound equipment following chamber quantitation protocols approved by the European Association of Cardiovascular Imaging. METHODS: A total of 734 (mean age: 45.8 +/- 13.3 years) healthy volunteers (320 men and 414 women) were enrolled at 22 collaborating institutions of the Normal Reference Ranges for Echocardiography (NORRE) study. A comprehensive echocardiographic examination was performed on all subjects following pre-defined protocols. There were no gender differences in age or cholesterol levels. Compared with men, women had significantly smaller body surface areas, and lower blood pressure. Quality of echocardiographic data sets was good to excellent in the majority of patients. Upper and lower reference limits were higher in men than in women. The reference values varied with age. These age-related changes persisted for most parameters after normalization for the body surface area. CONCLUSION: The NORRE study provides useful two-dimensional echocardiographic reference ranges for cardiac chamber quantification. These data highlight the need for body size normalization that should be performed together with age-and gender-specific assessment for the most echocardiographic parameters.
Disciplines :
Cardiovascular & respiratory systems
Author, co-author :
Kou, Seisyou
Caballero, Luis
DULGHERU, Raluca Elena 
Voilliot, Damien
De Sousa, Carla
Kacharava, George
Athanassopoulos, George
Barone, Daniele
Baroni, Monica
Cardim, Nuno
Gomez De Diego, Jose Juan
Hagendorff, Andreas
Henri, Christine
Hristova, Krasimira
Lopez, Teresa
Magne, Julien ;  Université de Liège - ULiège > Département des sciences cliniques > Cardiologie - Pathologie spéciale et réhabilitation
De La Morena, Gonzalo
Popescu, Bogdan Alexandru
Penicka, Martin
Ozyigit, Tolga
Rodrigo Carbonero, Jose David
Salustri, Alessandro
Van De Veire, Nico
Von Bardeleben, Ralph Stephan
Vinereanu, Dragos
Voigt, Jens-Uwe
Zamorano, Jose Luis
Donal, Erwan
Lang, Roberto M.
Badano, Luigi P.
Lancellotti, Patrizio  ;  Université de Liège - ULiège > Département des sciences cliniques > Imagerie cardiaque fonctionnelle par échographie
More authors (21 more) Less
Language :
English
Title :
Echocardiographic reference ranges for normal cardiac chamber size: results from the NORRE study.
Publication date :
2014
Journal title :
European Heart Journal. Cardiovascular Imaging
ISSN :
2047-2404
eISSN :
2047-2412
Publisher :
Oxford University Press, United Kingdom
Volume :
15
Issue :
6
Pages :
680-690
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 21 June 2014

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