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Article (Scientific journals)
Recent developments in the field of arrow and dart poisons
Philippe, Geneviève  ; Angenot, Luc 
2005 • In Journal of Ethnopharmacology, 100 (1-2), p. 85-91
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Keywords :
dart poisons; arrow poisons; alkaloids; cardiac glycosides; frog skin
Abstract :
[en] Arrow and dart poisons, considered as conventional natural sources for future drug discovery, have already provided numerous biologically active molecules used as drugs in therapeutic applications or in pharmacological research. Plants containing alkaloids or cardiotonic glycosides have generally been the main ingredients responsible for the efficacy of these poisons, although some animals, such as frogs, have also been employed. This paper, without being exhaustive, reports the greater strides made during the past 15 years in the understanding of the chemical nature and biological properties of arrow and dart poison constituents. Examples both of promising biological properties shown by these molecules and of crucial discoveries achieved by their use as pharmacological tools are given. Further studies of these toxic principles are likely to enable scientists to find new valuable lead compounds, useful in many fields of research, like oncology, inflammation and infectious diseases. 2005 Elsevier Ireland Ltd. All rights reserved.
Disciplines :
Pharmacy, pharmacology & toxicology
Chemistry
Phytobiology (plant sciences, forestry, mycology...)
Author, co-author :
Philippe, Geneviève ;  Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Angenot, Luc  ;  Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Language :
English
Title :
Recent developments in the field of arrow and dart poisons
Publication date :
22 August 2005
Journal title :
Journal of Ethnopharmacology
ISSN :
0378-8741
eISSN :
1872-7573
Publisher :
Elsevier Ireland Ltd, Clare, Ireland
Volume :
100
Issue :
1-2
Pages :
85-91
Peer reviewed :
Peer Reviewed verified by ORBi

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