Recent developments in the field of arrow and dart poisons

Philippe, Geneviève; Angenot, Luc

doi:10.1016/j.jep.2005.05.022

Reference : Recent developments in the field of arrow and dart poisons


	Document type :	Scientific journals : Article
	Discipline(s) :	Human health sciences : Pharmacy, pharmacology & toxicology Physical, chemical, mathematical & earth Sciences : Chemistry Life sciences : Phytobiology (plant sciences, forestry, mycology...)
	To cite this reference:	http://hdl.handle.net/2268/16897

Title :	Recent developments in the field of arrow and dart poisons
Language :	English
Author, co-author :	Philippe, Geneviève [Université de Liège - ULiège > Département de pharmacie > Pharmacognosie >]
	Angenot, Luc [Université de Liège - ULiège > Département de pharmacie > Pharmacognosie >]
Publication date :	22-Aug-2005
Journal title :	Journal of Ethnopharmacology
Publisher :	Elsevier Ireland Ltd
Volume :	100
Issue/season :	1-2
Pages :	85-91
Peer reviewed :	Yes (verified by ORBi)
Audience :	International
ISSN :	0378-8741
e-ISSN :	1872-7573
City :	Clare
Country :	Ireland
Keywords :	[en] dart poisons ; arrow poisons ; alkaloids ; cardiac glycosides ; frog skin
Abstract :	[en] Arrow and dart poisons, considered as conventional natural sources for future drug discovery, have already provided numerous biologically active molecules used as drugs in therapeutic applications or in pharmacological research. Plants containing alkaloids or cardiotonic glycosides have generally been the main ingredients responsible for the efficacy of these poisons, although some animals, such as frogs, have also been employed. This paper, without being exhaustive, reports the greater strides made during the past 15 years in the understanding of the chemical nature and biological properties of arrow and dart poison constituents. Examples both of promising biological properties shown by these molecules and of crucial discoveries achieved by their use as pharmacological tools are given. Further studies of these toxic principles are likely to enable scientists to find new valuable lead compounds, useful in many fields of research, like oncology, inflammation and infectious diseases. 2005 Elsevier Ireland Ltd. All rights reserved.
Permalink :	http://hdl.handle.net/2268/16897
DOI :	10.1016/j.jep.2005.05.022

File(s) associated to this reference

Fulltext file(s):

	File	Commentary	Version	Size	Access
Open access	Arrow poisons.doc		Author postprint	249 kB	View/Open

All documents in ORBi are protected by a user license.

Dspace v1.5