Adhesion therapeutique aux antiagregants chez le patient coronarien.

Aspirin/therapeutic use; Coronary Artery Disease/drug therapy; Humans; Medication Adherence/statistics & numerical data; Platelet Aggregation Inhibitors/therapeutic use; Ticlopidine/analogs & derivatives/therapeutic use

Abstract :

[en] Clinical benefit of antiplatelet therapy is established for cardiovascular disease and percutaneous coronary intervention (PCI). Dual antiplatelet therapy is used to optimize platelet inhibition. However, cardiovascular events still occur. Aspirin/clopidogrel resistance and poor compliance are the main factors implied in recurrent events. Compliance to dual antiplatelet therapy is particularly relevant during the first 6 months following acute coronary syndromes and PCI. Furthermore, several studies have shown association between antiplatelet resistance and poor compliance. Additionally, late (1 month to 1 year) and very late (> 1 year) stent thromboses are intimately linked to interruption of antiplatelet treatment. In this article we review the latest data about compliance, resistance and recommendations regarding antiplatelet therapy.

Disciplines :

Cardiovascular & respiratory systems

Author, co-author :

Legrand, D.

Legrand, Victor ; Université de Liège - ULiège > Département des sciences cliniques > Cardiologie

Language :

French

Title :

Adhesion therapeutique aux antiagregants chez le patient coronarien.

Alternative titles :

[en] Adherence to antiplatelet therapy in patients with coronary artery disease

Publication date :

2010

Journal title :

Revue Médicale de Liège

ISSN :

0370-629X

eISSN :

2566-1566

Publisher :

Université de Liège. Revue Médicale de Liège, Liège, Belgium

Volume :

Issue :

5-6

Pages :

304-10

Peer reviewed :

Peer reviewed

Available on ORBi :

since 26 May 2014

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474 (2 by ULiège)

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