Reference : Adhesion therapeutique aux antiagregants chez le patient coronarien.
Scientific journals : Article
Human health sciences : Cardiovascular & respiratory systems
Adhesion therapeutique aux antiagregants chez le patient coronarien.
[en] Adherence to antiplatelet therapy in patients with coronary artery disease
Legrand, D. [> >]
Legrand, Victor mailto [Université de Liège - ULiège > Département des sciences cliniques > Cardiologie >]
Revue Médicale de Liège
Yes (verified by ORBi)
[en] Aspirin/therapeutic use ; Coronary Artery Disease/drug therapy ; Humans ; Medication Adherence/statistics & numerical data ; Platelet Aggregation Inhibitors/therapeutic use ; Ticlopidine/analogs & derivatives/therapeutic use
[en] Clinical benefit of antiplatelet therapy is established for cardiovascular disease and percutaneous coronary intervention (PCI). Dual antiplatelet therapy is used to optimize platelet inhibition. However, cardiovascular events still occur. Aspirin/clopidogrel resistance and poor compliance are the main factors implied in recurrent events. Compliance to dual antiplatelet therapy is particularly relevant during the first 6 months following acute coronary syndromes and PCI. Furthermore, several studies have shown association between antiplatelet resistance and poor compliance. Additionally, late (1 month to 1 year) and very late (> 1 year) stent thromboses are intimately linked to interruption of antiplatelet treatment. In this article we review the latest data about compliance, resistance and recommendations regarding antiplatelet therapy.

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