Study of antirestenosis with the BiodivYsio dexamethasone-eluting stent (STRIDE): A first-in-human multicenter pilot trial

Liu, X. S.; Huang, Y. M.; Hanet, C.; Vandormael, M.; Legrand, Victor; Dens, J.; Vandenbossche, J. L.; Missault, L.; Vrints, C.; De Scheerder, I.

doi:10.1002/ccd.10636

Article (Scientific journals)

Study of antirestenosis with the BiodivYsio dexamethasone-eluting stent (STRIDE): A first-in-human multicenter pilot trial

Liu, X. S.; Huang, Y. M.; Hanet, C. et al.

2003 • In Catheterization and Cardiovascular Interventions, 60 (2), p. 172-178

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https://hdl.handle.net/2268/168208

DOI
10.1002/ccd.10636

PubMed
14517920

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Keywords :

drug-eluting stent; dexamethasone

Abstract :

[en] The aim of this multicenter pilot study was to evaluate the acute safety and efficacy of the dexamethasone-eluting stent (0.5 mug/mm(2) of stent) implanted in patients with de novo single-vessel disease. This study included 71 patients, 42% of whom had unstable angina pectoris. An appropriately sized BiodivYsio Matrix Lo stent loaded with a total dexamethasone dose of 0.5 mug/mm(2) of stent was used. Technical device success rate was 95%. Six-month MACE occurred in two patients (3.3%). Binary restenosis rate was 13.3%. Late loss was 0.45. Late loss and percent diameter stenosis were lower in the unstable angina pectoris patients compared to the stable patients (0.32 +/- 0.39 vs. 0.60 +/- 0.55 mm, P < 0.07, and 26.86 +/- 14 vs. 38.40 +/- 16%, P < 0.02). This study demonstrated the feasibility and safety of the implantation of a dexamethasone-eluting stent and its effect on in-stent neointimal hyperplasia. (C) 2003 Wiley-Liss, Inc.

Disciplines :

Cardiovascular & respiratory systems

Author, co-author :

Liu, X. S.

Huang, Y. M.

Hanet, C.

Vandormael, M.

Legrand, Victor ; Université de Liège - ULiège > Département des sciences cliniques > Cardiologie

Dens, J.

Vandenbossche, J. L.

Missault, L.

Vrints, C.

De Scheerder, I.

Language :

English

Title :

Study of antirestenosis with the BiodivYsio dexamethasone-eluting stent (STRIDE): A first-in-human multicenter pilot trial

Publication date :

October 2003

Journal title :

Catheterization and Cardiovascular Interventions

ISSN :

1522-1946

eISSN :

1522-726X

Publisher :

Wiley Liss, Inc., New York, United States - New York

Volume :

Issue :

Pages :

172-178

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 22 May 2014

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