[en] The guidance of human sperm cells under con finement in quasi 2D microchambers is investigated using a purely physical method to control their distribution. Transport property measurements and simulations are performed with diluted sperm populations, for which eff ects of geometrical guidance and concentration are studied in detail. In particular, a trapping transition at convex angular wall features is identi ed and analyzed. We also show that highly efficient microratchets can be fabricated by using curved asymmetric obstacles to take advantage of the spermatozoa specifi c swimming strategy.
Disciplines :
Physics
Author, co-author :
Guidobaldi, Alejandro; Universidad Nacional de Cordoba
Jeyaram, Yogesh; Katholieke Universiteit Leuven - KUL
Berdakin, Ivan; Universidad Nacional de Cordoba, Argentina
Moshchalkov, Victor V.; Katholieke Universiteit Leuven - KUL
Condat, Carlos; Universidad Nacional de Cordoba, Argentina
Marconi, Veronica I.; Universidad Nacional de Cordoba, Argentina
Giojalas, Laura; Universidad Nacional de Cordoba, Argentina
Silhanek, Alejandro ; Université de Liège - ULiège > Département de physique > Physique de la matière condensée
Language :
English
Title :
Geometrical guidance and trapping transition of human sperm cells
Publication date :
28 March 2014
Journal title :
Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics
ISSN :
1539-3755
eISSN :
1550-2376
Publisher :
American Physical Society, College Park, United States - Maryland
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