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Article (Scientific journals)
Multiple System Organ Failure after open-heart surgery in infants and children
Seghaye, Marie-Christine; Engelhardt, W.; Grabitz, R. G. et al.
1993In Thoracic and Cardiovascular Surgeon, 41 (1), p. 49-53
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Keywords :
Cardiac Surgical Procedures; Child; Child, Preschool; Female; Germany, West; Human; Incidence; Infant; Male; Multiple Organ Failure; Postoperative Complications; Retrospective Studies; Time Factors; Treatment Outcome
Abstract :
[en] Between January 1985 and March 1989 we retrospectively observed Multiple System Organ Failure (MSOF) in 16 of 460 children (3.5%) who underwent cardiac surgery with cardiopulmonary bypass for congenital heart disease. MSOF was arbitrarily defined as a clinical entity with failure of two or more vital organ systems associated with high fever, thrombocytopenia, and cardiocirculatory insufficiency and occurring within the first postoperative week. In 13 children the first clinical manifestations of MSOF were evident on the first postoperative day and in the other 3 on the second or third postoperative day. All children showed acute renal failure, acute hepatic failure, high fever, and thrombocytopenia. Most of them showed respiratory insufficiency and neurological involvement. Seven of the 16 children died. Four of the 9 surviving patients had neurological sequelae still present 6 months after the operation, and the others recovered completely.
Disciplines :
Pediatrics
Cardiovascular & respiratory systems
Author, co-author :
Seghaye, Marie-Christine ;  Rheinisch - Westfälische Technische Hochschule Aachen - RWTH > Pediatric Cardiology
Engelhardt, W.;  Klinik fur Kinderkardiologie, RWTH, Pauwelsstrasse, D-5100 Aachen, Germany > Pediatric Cardiology
Grabitz, R. G.;  Klinik fur Kinderkardiologie, RWTH, Pauwelsstrasse, D-5100 Aachen, Germany > Pediatric Cardiology
Faymonville, Marie-Elisabeth ;  Université de Liège - ULiège > Département des sciences cliniques > Médecine de la douleur : algologie et hypnose
Hornchen, H.;  Klinik fur Kinderkardiologie, RWTH, Pauwelsstrasse, D-5100 Aachen, Germany > Pediatric Intensive Care
Messmer, B. J.;  Klinik fur Kinderkardiologie, RWTH, Pauwelsstrasse, D-5100 Aachen, Germany > Thoracic and Cardiovascular Surgery
Von Bernuth, G.;  Klinik fur Kinderkardiologie, RWTH, Pauwelsstrasse, D-5100 Aachen, Germany > Pediatric Cardiology
Language :
English
Title :
Multiple System Organ Failure after open-heart surgery in infants and children
Publication date :
February 1993
Journal title :
Thoracic and Cardiovascular Surgeon
ISSN :
0171-6425
eISSN :
1439-1902
Publisher :
Thieme
Volume :
41
Issue :
1
Pages :
49-53
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 07 February 2014

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