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Abstract :
[en] RATIONALE AND OBJECTIVES: The authors evaluate the use of a new device for interventional creation of atrial septal defects (ASD) working with high-frequency alternating current in an in vitro study with porcine atria. METHODS: The device consists of a symmetrical cage of six superelastic monofile wires, including a microthermistor that is placed via a catheter into a punctured hole in the porcine foramen ovale. The device is used as a differential electrode for monopolar, temperature-controlled application of high-frequency alternating current for thermal modelling of ASD. RESULTS: Application of current for 60 seconds caused temperature-dependent, sized ASDs. CONCLUSION: In vivo animal studies to evaluate possible side effects and long term patency of the ASDs are justified and warranted.
Grabitz, R. G.; Rheinisch - Westfälische Technische Hochschule Aachen - RWTH > Pediatric Cardiology
Handt, S.; Rheinisch - Westfälische Technische Hochschule Aachen - RWTH > Pathology
Vanopbroeke, H. J.; Rheinisch - Westfälische Technische Hochschule Aachen - RWTH > Pediatric Cardiology
Franke, A.; Rheinisch - Westfälische Technische Hochschule Aachen - RWTH > Cardiology
Osypka, P.; GmbH Medizintechnik, Basler Stra[beta]e 109, Grenzach-Wyhlen, Germany
von Bernuth, G.; Rheinisch - Westfälische Technische Hochschule Aachen - RWTH > Pediatric Cardiology
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