Reference : Testosterone metabolism in discrete areas of the hypothalamus and adjacent brain regi...
Scientific journals : Article
Human health sciences : Endocrinology, metabolism & nutrition
Life sciences : Zoology
Social & behavioral sciences, psychology : Neurosciences & behavior
Testosterone metabolism in discrete areas of the hypothalamus and adjacent brain regions of male and female Japanese quail (Coturnix coturnix Japonica).
Schumacher, M. [> > > >]
Contenti, E. [> > > >]
Balthazart, Jacques mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biologie de la différenciation sexuelle du cerveau >]
Brain Research
Yes (verified by ORBi)
[en] Animals ; Brain/metabolism ; Coturnix/metabolism ; Female ; Hypothalamus/enzymology/metabolism ; Male ; Oxidoreductases/metabolism ; Quail/metabolism ; Sex Factors ; Testosterone/metabolism
[en] The metabolism of testosterone in small regions of the hypothalamus was studied by an in vitro radioenzymatic assay in male and female Japanese quail. 5 beta-reduction was the most important metabolic pathway. This enzymatic activity is not evenly distributed in the brain: it shows a rostral to caudal decrease. There is some suggestion that 5 beta-reduction could be more active in females than in males which could contribute to the behavioral dimorphism in this species.

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