Reference : Le trouble bipolaire: une affection bien complexe.
Scientific journals : Article
Human health sciences : Psychiatry
http://hdl.handle.net/2268/162498
Le trouble bipolaire: une affection bien complexe.
French
[en] Bipolar disorder: a multifactorial disease
PITCHOT, William mailto [Centre Hospitalier Universitaire de Liège - CHU > > Psychiatrie et psychologie médicale >]
Scantamburlo, Gabrielle mailto [Université de Liège - ULiège > Département des sciences cliniques > Psychiatrie et psychologie médicale >]
Ansseau, Marc mailto [Université de Liège - ULiège > Département des sciences cliniques > Psychiatrie et psychologie médicale >]
Souery, D [> >]
2012
Revue Médicale de Liège
67
5-6
366-73
Yes (verified by ORBi)
National
0370-629X
Belgium
[en] Animals ; Bipolar Disorder/epidemiology/etiology/genetics/therapy ; Causality ; Disease Susceptibility ; Environment ; Gene-Environment Interaction ; Humans ; Risk Factors
[en] Bipolar disorder is a multifactorial disease with a strong genetic component. However, environmental factors also play a role in the onset of the disease and in manic and depressive recurrence. The onset of the disorder is the consequence of a complex interaction between genetic and environmental factors. This gene-environment interaction is well illustrated by the influence of childhood trauma on the clinical expression of the disease in terms of age of onset, comorbidity and suicide. The complexity and heterogeneity of bipolar disorder require the identification of homogenous sub-groups with the use of biomarkers that could help reduce the etiological heterogeneity and better target the therapeutical options.
http://hdl.handle.net/2268/162498

File(s) associated to this reference

Fulltext file(s):

FileCommentaryVersionSizeAccess
Restricted access
Le Trouble bipolaire, Rev Med, 2012,67,5.6.pdfPublisher postprint5.14 MBRequest copy

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.