Skin viscoelasticity during hormone replacement therapy for climacteric ageing.

[en] BACKGROUND: Climacteric ageing refers to the period of women's life centred by the perimenopause. This step of life is responsible for initiating skin atrophic withering and slackness responsible for changes in the viscoelasticity of the dermal connective tissue. Some women benefit from hormone replacement therapy (HRT) for controlling some unpleasant internal climacteric changes (osteoporosis, vasomotor instability, ...). OBJECTIVE: To investigate some corrective effects of HRT on the functional damages in the dermal tensile strength. PATIENTS AND METHODS: This study was performed on 200 healthy Caucasian women. In vivo skin viscoelasticity was assessed using the suction method. RESULTS: Skin distensibility and hysteresis appeared increased at menopause with or without HRT. By contrast, the biological elasticity significantly decreased out of HRT. CONCLUSION: Some drugs and cosmetics might attempt at improving such viscoelastic attributes of the skin at menopause.

Disciplines :

Dermatology

Author, co-author :

PIERARD, Gérald ; Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie

Hermanns-Lê, Trinh ; Université de Liège - ULiège > Département des sciences cliniques > Dermatopathologie

PAQUET, Philippe ; Centre Hospitalier Universitaire de Liège - CHU > Dermatologie

Franchimont, Claudine ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques

Language :

English

Title :

Skin viscoelasticity during hormone replacement therapy for climacteric ageing.

Publication date :

2014

Journal title :

International Journal of Cosmetic Science

ISSN :

0142-5463

eISSN :

1468-2494

Publisher :

Blackwell Publishing

Volume :

Pages :

88-92

Peer reviewed :

Peer Reviewed verified by ORBi

Commentary :

Available on ORBi :

since 13 January 2014

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