Reference : Premier episode de rejet aigu apres transplantation renale: etude des caracteristique...
Scientific journals : Article
Human health sciences : Surgery
http://hdl.handle.net/2268/15025
Premier episode de rejet aigu apres transplantation renale: etude des caracteristiques histopathologiques en fonction du risque immunologique du patient.
French
[en] First acute rejection episode after renal transplantation: study of the histopathological characteristics according to the immunological risk
Ghisdal, Lidia [> > > >]
Touchard, Guy [> > > >]
Goujon, Jean-Michel [> > > >]
Buob, David [> > > >]
Durand, Dominique [> > > >]
Mourad, Georges [> > > >]
Lang, Philippe [> > > >]
Kessler, Michele [> > > >]
Snanoudj, Renaud [> > > >]
Berthoux, Francois [> > > >]
Merville, Pierre [> > > >]
Ouali, Nacera [> > > >]
Squifflet, Jean-Paul mailto [Centre Hospitalier Universitaire de Liège - CHU > > Chirurgie abdominale- endocrinienne et de transplantation >]
Bayle, Francois [> > > >]
Bourgeon, Bruno [> > > >]
Rifle, Gerard [> > > >]
Peeters, Patrick [> > > >]
Delahousse, Michel [> > > >]
Legendre, Christophe [> > > >]
Bourbigot, Bernard [> > > >]
Noel, Christian [> > > >]
Abramowicz, Daniel [> > > >]
2008
Néphrologie et Thérapeutique
Elsevier
4
3
173-80
Yes (verified by ORBi)
International
1769-7255
1872-9177
Paris
France
[en] Adult ; Biopsy ; Complement C4b/metabolism ; Female ; Graft Rejection/immunology ; Humans ; Kidney/metabolism/pathology ; Kidney Transplantation ; Male ; Middle Aged ; Neutrophils/metabolism ; Retrospective Studies ; Risk Assessment
[en] Renal allograft biopsies (n=34) of two different populations of patients according to the immunological risk (high versus low-risk) have been compared retrospectively. The presence of polymorphonuclear leukocytes in peritubular capillaries was more frequent in the high-risk group. The C4d staining was positive in 10% of the low-risk patients and in 50% of the high-risk patients (P=0.03). There were more early graft loss, renal infarctions, interstitial hemorrhage, severe glomerulitis, neutrophilic glomerulitis and Banff III grade rejection in the positive C4d group. In conclusion, half of the immunized patients had a humoral rejection, patients with a C4d positive rejection had more early graft loss and more severe histological lesions.
Researchers ; Professionals ; Students ; General public
http://hdl.handle.net/2268/15025
10.1016/j.nephro.2008.02.001

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