R.J. Nibbs, S.M. Wylie, I.B. Pragnell, and G.J. Graham Cloning and characterization of a novel murine beta chemokine receptor, D6. Comparison to three other related macrophage inflammatory protein-1alpha receptors, CCR-1, CCR-3, and CCR-5 J Biol Chem 272 19 1997 12495 12504 [Epub 1997/05/09]
K. Neote, W. Darbonne, J. Ogez, R. Horuk, and T.J. Schall Identification of a promiscuous inflammatory peptide receptor on the surface of red blood cells J Biol Chem 268 17 1993 12247 12249 [Epub 1993/06/15]
B. Moser, M. Wolf, A. Walz, and P. Loetscher Chemokines: multiple levels of leukocyte migration control Trends Immunol 25 2 2004 75 84 [Epub 2004/04/23]
F. Balkwill Chemokine biology in cancer Semin Immunol 15 1 2003 49 55 [Epub 2002/12/24]
M.B. Furie, and G.J. Randolph Chemokines and tissue injury Am J Pathol 146 6 1995 1287 1301 [Epub 1995/06/01]
Y. Le, Y. Zhou, P. Iribarren, and J. Wang Chemokines and chemokine receptors: their manifold roles in homeostasis and disease Cell Mol Immunol 1 2 2004 95 104 [Epub 2005/10/11]
M. Baggiolini Chemokines and leukocyte traffic Nature 392 6676 1998 565 568 [Epub 1998/04/29]
C. Gerard, and B.J. Rollins Chemokines and disease Nat Immunol 2 2 2001 108 115 [Epub 2001/03/29]
Y. Feng, C.C. Broder, P.E. Kennedy, and E.A. Berger HIV-1 entry cofactor: functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor Science 272 5263 1996 872 877 [Epub 1996/05/10]
E.A. Berger HIV entry and tropism: the chemokine receptor connection AIDS 11 Suppl. A 1997 S3 S16 [Epub 1997/01/01]
M.P. Crump, J.H. Gong, P. Loetscher, K. Rajarathnam, A. Amara, and F. Arenzana-Seisdedos Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1 EMBO J 16 23 1997 6996 7007 [Epub 1998/01/31]
F.S. Monteclaro, and I.F. Charo The amino-terminal extracellular domain of the MCP-1 receptor, but not the RANTES/MIP-1alpha receptor, confers chemokine selectivity. Evidence for a two-step mechanism for MCP-1 receptor activation J Biol Chem 271 32 1996 19084 19092 [Epub 1996/08/09]
I. Clark-Lewis, K.S. Kim, K. Rajarathnam, J.H. Gong, B. Dewald, and B. Moser Structure-activity relationships of chemokines J Leukoc Biol 57 5 1995 703 711 [Epub 1995/05/01]
E.J. Fernandez, and E. Lolis Structure, function, and inhibition of chemokines Annu Rev Pharmacol Toxicol 42 2002 469 499 [Epub 2002/01/25]
A. Zlotnik, and O. Yoshie Chemokines: a new classification system and their role in immunity Immunity 12 2 2000 121 127 [Epub 2000/03/14]
B. Wu, E.Y. Chien, C.D. Mol, G. Fenalti, W. Liu, and V. Katritch Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists Science 330 6007 2010 1066 1071 [Epub 2010/10/12]
G.J. LaRosa, K.M. Thomas, M.E. Kaufmann, R. Mark, M. White, and L. Taylor Amino terminus of the interleukin-8 receptor is a major determinant of receptor subtype specificity J Biol Chem 267 35 1992 25402 25406 [Epub 1992/12/15]
C. Blanpain, B.J. Doranz, J. Vakili, J. Rucker, C. Govaerts, and S.S. Baik Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein J Biol Chem 274 49 1999 34719 34727 [Epub 1999/11/27]
C.A. Hebert, A. Chuntharapai, M. Smith, T. Colby, J. Kim, and R. Horuk Partial functional mapping of the human interleukin-8 type A receptor. Identification of a major ligand binding domain J Biol Chem 268 25 1993 18549 18553 [Epub 1993/09/05]
L. Wu, N. Ruffing, X. Shi, W. Newman, D. Soler, and C.R. Mackay Discrete steps in binding and signaling of interleukin-8 with its receptor J Biol Chem 271 49 1996 31202 31209 [Epub 1996/12/06]
R.B. Gayle 3rd, P.R. Sleath, S. Srinivason, C.W. Birks, K.S. Weerawarna, and D.P. Cerretti Importance of the amino terminus of the interleukin-8 receptor in ligand interactions J Biol Chem 268 10 1993 7283 7289 [Epub 1993/04/05]
R.A. Colvin, G.S. Campanella, L.A. Manice, and A.D. Luster CXCR3 requires tyrosine sulfation for ligand binding and a second extracellular loop arginine residue for ligand-induced chemotaxis Mol Cell Biol 26 15 2006 5838 5849 [Epub 2006/07/19]
G.N. Prado, K. Suetomi, D. Shumate, C. Maxwell, A. Ravindran, and K. Rajarathnam Chemokine signaling specificity: essential role for the N-terminal domain of chemokine receptors Biochemistry 46 31 2007 8961 8968 [Epub 2007/07/17]
L. Rajagopalan, and K. Rajarathnam Ligand selectivity and affinity of chemokine receptor CXCR1. Role of N-terminal domain J Biol Chem 279 29 2004 30000 30008 [Epub 2004/05/11]
E. Kokkoli, R.W. Kasinskas, A. Mardilovich, and A. Garg Fractalkine targeting with a receptor-mimicking peptide-amphiphile Biomacromolecules 6 3 2005 1272 1279 [Epub 2005/05/10]
R.T. Clubb, J.G. Omichinski, G.M. Clore, and A.M. Gronenborn Mapping the binding surface of interleukin-8 complexed with an N-terminal fragment of the type 1 human interleukin-8 receptor FEBS Lett 338 1 1994 93 97 [Epub 1994/01/24]
N.J. Skelton, C. Quan, D. Reilly, and H. Lowman Structure of a CXC chemokine-receptor fragment in complex with interleukin-8 Structure 7 2 1999 157 168 [Epub 1999/06/16]
L.S. Mizoue, J.F. Bazan, E.C. Johnson, and T.M. Handel Solution structure and dynamics of the CX3C chemokine domain of fractalkine and its interaction with an N-terminal fragment of CX3CR1 Biochemistry 38 5 1999 1402 1414 [Epub 1999/02/04]
C.T. Veldkamp, C. Seibert, F.C. Peterson, N.B. De la Cruz, J.C. Haugner 3rd, and H. Basnet Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12 Sci Signal 1 37 2008 ra4 [Epub 2008/09/19]
C.T. Veldkamp, C. Seibert, F.C. Peterson, T.P. Sakmar, and B.F. Volkman Recognition of a CXCR4 sulfotyrosine by the chemokine stromal cell-derived factor-1alpha (SDF-1alpha/CXCL12) J Mol Biol 359 5 2006 1400 1409 [Epub 2006/05/27]
J. Ye, L.L. Kohli, and M.J. Stone Characterization of binding between the chemokine eotaxin and peptides derived from the chemokine receptor CCR3 J Biol Chem 275 35 2000 27250 27257 [Epub 2000/06/22]
M. Love, J.L. Sandberg, J.J. Ziarek, K.P. Gerarden, R.R. Rode, and D.R. Jensen Solution structure of CCL21 and identification of a putative CCR7 binding site Biochemistry 51 3 2012 733 735 [Epub 2012/01/10]
E.K. Gozansky, J.M. Louis, M. Caffrey, and G.M. Clore Mapping the binding of the N-terminal extracellular tail of the CXCR4 receptor to stromal cell-derived factor-1alpha J Mol Biol 345 4 2005 651 658 [Epub 2004/12/14]
A. Datta, and M.J. Stone Soluble mimics of a chemokine receptor: chemokine binding by receptor elements juxtaposed on a soluble scaffold Protein Sci 12 11 2003 2482 2491 [Epub 2003/10/24]
A. Datta-Mannan, and M.J. Stone Chemokine-binding specificity of soluble chemokine-receptor analogues: identification of interacting elements by chimera complementation Biochemistry 43 46 2004 14602 14611 [Epub 2004/11/17]
S.H. Park, F. Casagrande, L. Cho, L. Albrecht, and S.J. Opella Interactions of interleukin-8 with the human chemokine receptor CXCR1 in phospholipid bilayers by NMR spectroscopy J Mol Biol 414 2 2011 194 203 [Epub 2011/10/25]
F.S. Monteclaro, and I.F. Charo The amino-terminal domain of CCR2 is both necessary and sufficient for high affinity binding of monocyte chemoattractant protein 1. Receptor activation by a pseudo-tethered ligand J Biol Chem 272 37 1997 23186 23190 [Epub 1997/09/12]
S.S. Karnik, C. Gogonea, S. Patil, Y. Saad, and T. Takezako Activation of G-protein-coupled receptors: a common molecular mechanism Trends Endocrinol Metabol 14 9 2003 431 437 [Epub 2003/10/29]
A.K. Samanta, S. Dutta, and E. Ali Modification of sulfhydryl groups of interleukin-8 (IL-8) receptor impairs binding of IL-8 and IL-8-mediated chemotactic response of human polymorphonuclear neutrophils J Biol Chem 268 9 1993 6147 6153 [Epub 1993/03/25]
L.S. Ai, and F. Liao Mutating the four extracellular cysteines in the chemokine receptor CCR6 reveals their differing roles in receptor trafficking, ligand binding, and signaling Biochemistry 41 26 2002 8332 8341 [Epub 2002/06/26]
C. Blanpain, B. Lee, J. Vakili, B.J. Doranz, C. Govaerts, and I. Migeotte Extracellular cysteines of CCR5 are required for chemokine binding, but dispensable for HIV-1 coreceptor activity J Biol Chem 274 27 1999 18902 18908 [Epub 1999/06/26]
Z. Luo, X. Fan, N. Zhou, M. Hiraoka, J. Luo, and H. Kaji Structure-function study and anti-HIV activity of synthetic peptide analogues derived from viral chemokine vMIP-II Biochemistry 39 44 2000 13545 13550 [Epub 2000/11/07]
S.R. Leong, R.C. Kabakoff, and C.A. Hebert Complete mutagenesis of the extracellular domain of interleukin-8 (IL-8) type A receptor identifies charged residues mediating IL-8 binding and signal transduction J Biol Chem 269 30 1994 19343 19348 [Epub 1994/07/29]
C. Limatola, S. Di Bartolomeo, M. Catalano, F. Trettel, S. Fucile, and L. Castellani Cysteine residues are critical for chemokine receptor CXCR2 functional properties Exp Cell Res 307 1 2005 65 75 [Epub 2005/06/01]
C. Tournamille, C. Le Van Kim, P. Gane, D. Blanchard, A.E. Proudfoot, and J.P. Cartron Close association of the first and fourth extracellular domains of the Duffy antigen/receptor for chemokines by a disulfide bond is required for ligand binding J Biol Chem 272 26 1997 16274 16280 [Epub 1997/06/27]
S. Rana, and T.J. Baranski Third extracellular loop (EC3)-N terminus interaction is important for seven-transmembrane domain receptor function: implications for an activation microswitch region J Biol Chem 285 41 2010 31472 31483 [Epub 2010/07/29]
D.J. Chabot, P.F. Zhang, G.V. Quinnan, and C.C. Broder Mutagenesis of CXCR4 identifies important domains for human immunodeficiency virus type 1 X4 isolate envelope-mediated membrane fusion and virus entry and reveals cryptic coreceptor activity for R5 isolates J Virol 73 8 1999 6598 6609 [Epub 1999/07/10]
M.J. Smit, S.A. Lira, and R. Leurs Chemokine receptors as drug targets 2011 Wiley-VCH Weinheim, Germany p. xxiv, 13, 384
J.W. Kehoe, and C.R. Bertozzi Tyrosine sulfation: a modulator of extracellular protein-protein interactions Chem Biol 7 3 2000 R57 R61 [Epub 2000/03/14]
A.A. Preobrazhensky, S. Dragan, T. Kawano, M.A. Gavrilin, I.V. Gulina, and L. Chakravarty Monocyte chemotactic protein-1 receptor CCR2B is a glycoprotein that has tyrosine sulfation in a conserved extracellular N-terminal region J Immunol 165 9 2000 5295 5303 [Epub 2000/10/25]
M. Farzan, T. Mirzabekov, P. Kolchinsky, R. Wyatt, M. Cayabyab, and N.P. Gerard Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry Cell 96 5 1999 667 676 [Epub 1999/03/25]
M. Farzan, G.J. Babcock, N. Vasilieva, P.L. Wright, E. Kiprilov, and T. Mirzabekov The role of post-translational modifications of the CXCR4 amino terminus in stromal-derived factor 1 alpha association and HIV-1 entry J Biol Chem 277 33 2002 29484 29489 [Epub 2002/05/30]
A.M. Fong, S.M. Alam, T. Imai, B. Haribabu, and D.D. Patel CX3CR1 tyrosine sulfation enhances fractalkine-induced cell adhesion J Biol Chem 277 22 2002 19418 19423 [Epub 2002/03/23]
J.M. Gao, R.L. Xiang, L. Jiang, W.H. Li, Q.P. Feng, and Z.J. Guo Sulfated tyrosines 27 and 29 in the N-terminus of human CXCR3 participate in binding native IP-10 Acta Pharmacol Sinica 30 2 2009 193 201 [Epub 2009/01/20]
H. Choe, M.J. Moore, C.M. Owens, P.L. Wright, N. Vasilieva, and W. Li Sulphated tyrosines mediate association of chemokines and Plasmodium vivax Duffy binding protein with the Duffy antigen/receptor for chemokines (DARC) Mol Microbiol 55 5 2005 1413 1422 [Epub 2005/02/22]
S. Hemmerich, C. Paavola, A. Bloom, S. Bhakta, R. Freedman, and D. Grunberger Identification of residues in the monocyte chemotactic protein-1 that contact the MCP-1 receptor, CCR2 Biochemistry 38 40 1999 13013 13025 [Epub 1999/10/21]
H. Choe, and M. Farzan Chapter 7. Tyrosine sulfation of HIV-1 coreceptors and other chemokine receptors Methods Enzymol 461 2009 147 170 [Epub 2009/06/02]
J.J. Ziarek, M.S. Heroux, C.T. Veldkamp, F.C. Peterson, and B.F. Volkman Sulfotyrosine recognition as marker for druggable sites in the extracellular space Int J Mol Sci 12 6 2011 3740 3756 [Epub 2011/07/13]
J.Z. Zhu, C.J. Millard, J.P. Ludeman, L.S. Simpson, D.J. Clayton, and R.J. Payne Tyrosine sulfation influences the chemokine binding selectivity of peptides derived from chemokine receptor CCR3 Biochemistry 50 9 2011 1524 1534 [Epub 2011/01/18]
L.S. Simpson, J.Z. Zhu, T.S. Widlanski, and M.J. Stone Regulation of chemokine recognition by site-specific tyrosine sulfation of receptor peptides Chem Biol 16 2 2009 153 161 [Epub 2009/02/28]
C. Seibert, C.T. Veldkamp, F.C. Peterson, B.T. Chait, B.F. Volkman, and T.P. Sakmar Sequential tyrosine sulfation of CXCR4 by tyrosylprotein sulfotransferases Biochemistry 47 43 2008 11251 11262 [Epub 2008/10/07]
J.R. Bundgaard, J. Vuust, and J.F. Rehfeld New consensus features for tyrosine O-sulfation determined by mutational analysis J Biol Chem 272 35 1997 21700 21705 [Epub 1997/08/29]
G.L. Rosenquist, and H.B. Nicholas Jr. Analysis of sequence requirements for protein tyrosine sulfation Protein Sci 2 2 1993 215 222 [Epub 1993/02/01]
M.J. Stone, S. Chuang, X. Hou, M. Shoham, and J.Z. Zhu Tyrosine sulfation: an increasingly recognised post-translational modification of secreted proteins Nat Biotechnol 25 5 2009 299 317 [Epub 2009/08/07]
F. Monigatti, E. Gasteiger, A. Bairoch, and E. Jung The Sulfinator: predicting tyrosine sulfation sites in protein sequences Bioinformatics 18 5 2002 769 770 [Epub 2002/06/07]
Y.B. Ouyang, J.T. Crawley, C.E. Aston, and K.L. Moore Reduced body weight and increased postimplantation fetal death in tyrosylprotein sulfotransferase-1-deficient mice J Biol Chem 277 26 2002 23781 23787 [Epub 2002/04/20]
A. Borghei, Y.B. Ouyang, A.D. Westmuckett, M.R. Marcello, C.P. Landel, and J.P. Evans Targeted disruption of tyrosylprotein sulfotransferase-2, an enzyme that catalyzes post-translational protein tyrosine O-sulfation, causes male infertility J Biol Chem 281 14 2006 9423 9431 [Epub 2006/02/14]
E. Koltsova, and K. Ley Tyrosine sulfation of leukocyte adhesion molecules and chemokine receptors promotes atherosclerosis Arterioscler Thromb Vasc Biol 29 11 2009 1709 1711 [Epub 2009/10/23]
L.M. Danan, Z. Yu, A.J. Hoffhines, K.L. Moore, and J.A. Leary Mass spectrometric kinetic analysis of human tyrosylprotein sulfotransferase-1 and -2 J Am Soc Mass Spectrom 19 10 2008 1459 1466 [Epub 2008/08/02]
E. Mishiro, Y. Sakakibara, M.C. Liu, and M. Suiko Differential enzymatic characteristics and tissue-specific expression of human TPST-1 and TPST-2 J Biochem 140 5 2006 731 737 [Epub 2006/10/10]
M. Grodecka, M. Czerwinski, M. Duk, E. Lisowska, and K. Wasniowska Analysis of recombinant Duffy protein-linked N-glycans using lectins and glycosidases Acta Biochim Pol 57 1 2010 49 53 [Epub 2010/03/18]
M. Czerwinski, J. Kern, M. Grodecka, M. Paprocka, A. Krop-Watorek, and K. Wasniowska Mutational analysis of the N-glycosylation sites of Duffy antigen/receptor for chemokines Biochem Biophys Res Commun 356 3 2007 816 821 [Epub 2007/03/27]
A. Ludwig, J.E. Ehlert, H.D. Flad, and E. Brandt Identification of distinct surface-expressed and intracellular CXC-chemokine receptor 2 glycoforms in neutrophils: N-glycosylation is essential for maintenance of receptor surface expression J Immunol 165 2 2000 1044 1052 [Epub 2000/07/06]
N. Bannert, S. Craig, M. Farzan, D. Sogah, N.V. Santo, and H. Choe Sialylated O-glycans and sulfated tyrosines in the NH2-terminal domain of CC chemokine receptor 5 contribute to high affinity binding of chemokines J Exp Med 194 11 2001 1661 1673 [Epub 2001/12/26]
C. Tournamille, A. Filipe, K. Wasniowska, P. Gane, E. Lisowska, and J.P. Cartron Structure-function analysis of the extracellular domains of the Duffy antigen/receptor for chemokines: characterization of antibody and chemokine binding sites Br J Haematol 122 6 2003 1014 1023 [Epub 2003/09/06]
D. Huskens, K. Princen, M. Schreiber, and D. Schols The role of N-glycosylation sites on the CXCR4 receptor for CXCL-12 binding and signaling and X4 HIV-1 viral infectivity Virology 363 2 2007 280 287 [Epub 2007/03/03]
A.J. Sloane, V. Raso, D.S. Dimitrov, X. Xiao, S. Deo, and N. Muljadi Marked structural and functional heterogeneity in CXCR4: separation of HIV-1 and SDF-1alpha responses Immunol Cell Biol 83 2 2005 129 143 [Epub 2005/03/08]
L. Duma, D. Haussinger, M. Rogowski, P. Lusso, and S. Grzesiek Recognition of RANTES by extracellular parts of the CCR5 receptor J Mol Biol 365 4 2007 1063 1075 [Epub 2006/11/15]
A. Brelot, N. Heveker, M. Montes, and M. Alizon Identification of residues of CXCR4 critical for human immunodeficiency virus coreceptor and chemokine receptor activities J Biol Chem 275 31 2000 23736 23744 [Epub 2000/05/29]
J.A. Katancik, A. Sharma, and E. de Nardin Interleukin 8, neutrophil-activating peptide-2 and GRO-alpha bind to and elicit cell activation via specific and different amino acid residues of CXCR2 Cytokine 12 10 2000 1480 1488 [Epub 2000/10/12]
A. Ravindran, P.R. Joseph, and K. Rajarathnam Structural basis for differential binding of the interleukin-8 monomer and dimer to the CXCR1 N-domain: role of coupled interactions and dynamics Biochemistry 48 37 2009 8795 8805 [Epub 2009/08/18]
L. Rajagopalan, and K. Rajarathnam Structural basis of chemokine receptor function - a model for binding affinity and ligand selectivity Biosci Rep 26 5 2006 325 339 [Epub 2006/10/07]
S. Haldar, H. Raghuraman, T. Namani, K. Rajarathnam, and A. Chattopadhyay Membrane interaction of the N-terminal domain of chemokine receptor CXCR1 Biochim Biophys Acta 1798 6 2010 1056 1061 [Epub 2010/03/17]
L.J. Drury, J.J. Ziarek, S. Gravel, C.T. Veldkamp, T. Takekoshi, and S.T. Hwang Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways Proc Natl Acad Sci USA 108 43 2011 17655 17660 [Epub 2011/10/13]
P.M. Murphy Viral antichemokines: from pathogenesis to drug discovery J Clin Invest 105 11 2000 1515 1517 [Epub 2000/06/07]
P.M. Murphy Viral exploitation and subversion of the immune system through chemokine mimicry Nat Immunol 2 2 2001 116 122 [Epub 2001/03/29]
P.S. Moore, C. Boshoff, R.A. Weiss, and Y. Chang Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV Science 274 5293 1996 1739 1744 [Epub 1996/12/06]
C. Boshoff, Y. Endo, P.D. Collins, Y. Takeuchi, J.D. Reeves, and V.L. Schweickart Angiogenic and HIV-inhibitory functions of KSHV-encoded chemokines Science 278 5336 1997 290 294 [Epub 1997/10/10]
T.N. Kledal, M.M. Rosenkilde, F. Coulin, G. Simmons, A.H. Johnsen, and S. Alouani A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus Science 277 5332 1997 1656 1659 [Epub 1997/09/12]
A.C. Liwang, Z.X. Wang, Y. Sun, S.C. Peiper, and P.J. Liwang The solution structure of the anti-HIV chemokine vMIP-II Protein Sci 8 11 1999 2270 2280 [Epub 1999/12/14]
L.H. Miller, S.J. Mason, J.A. Dvorak, M.H. McGinniss, and I.K. Rothman Erythrocyte receptors for (Plasmodium knowlesi) malaria: Duffy blood group determinants Science 189 4202 1975 561 563 [Epub 1975/08/15]
L.H. Miller, S.J. Mason, D.F. Clyde, and M.H. McGinniss The resistance factor to Plasmodium vivax in blacks. The Duffy-blood-group genotype, FyFy N Engl J Med 295 6 1976 302 304 [Epub 1976/08/05]
R. Horuk, C.E. Chitnis, W.C. Darbonne, T.J. Colby, A. Rybicki, and T.J. Hadley A receptor for the malarial parasite Plasmodium vivax: the erythrocyte chemokine receptor Science 261 5125 1993 1182 1184 [Epub 1993/08/27]
I. Comerford, and R.J. Nibbs Post-translational control of chemokines: a role for decoy receptors? Immunol Lett 96 2 2005 163 174 [Epub 2004/12/09]
C.E. Chitnis, and L.H. Miller Identification of the erythrocyte binding domains of Plasmodium vivax and Plasmodium knowlesi proteins involved in erythrocyte invasion J Exp Med 180 2 1994 497 506 [Epub 1994/08/01]
C.E. Chitnis, A. Chaudhuri, R. Horuk, A.O. Pogo, and L.H. Miller The domain on the Duffy blood group antigen for binding Plasmodium vivax and P. knowlesi malarial parasites to erythrocytes J Exp Med 184 4 1996 1531 1536 [Epub 1996/10/01]
J.D. Batchelor, J.A. Zahm, and N.H. Tolia Dimerization of Plasmodium vivax DBP is induced upon receptor binding and drives recognition of DARC Nat Struct Mol Biol 18 8 2011 908 914 [Epub 2011/07/12]
H. Choe, M. Farzan, Y. Sun, N. Sullivan, B. Rollins, and P.D. Ponath The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates Cell 85 7 1996 1135 1148 [Epub 1996/06/28]
G. Alkhatib, C. Combadiere, C.C. Broder, Y. Feng, P.E. Kennedy, and P.M. Murphy CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1 Science 272 5270 1996 1955 1958 [Epub 1996/06/28]
B.J. Doranz, J. Rucker, Y. Yi, R.J. Smyth, M. Samson, and S.C. Peiper A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors Cell 85 7 1996 1149 1158 [Epub 1996/06/28]
T. Dragic, V. Litwin, G.P. Allaway, S.R. Martin, Y. Huang, and K.A. Nagashima HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5 Nature 381 6584 1996 667 673 [Epub 1996/06/20]
E.O. Freed, and M.A. Martin The role of human immunodeficiency virus type 1 envelope glycoproteins in virus infection J Biol Chem 270 41 1995 23883 23886 [Epub 1995/10/13]
J.P. Moore, A. Trkola, and T. Dragic Co-receptors for HIV-1 entry Curr Opin Immunol 9 4 1997 551 562 [Epub 1997/08/01]
A. Trkola, T. Dragic, J. Arthos, J.M. Binley, W.C. Olson, and G.P. Allaway CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5 Nature 384 6605 1996 184 187 [Epub 1996/11/14]
L. Wu, N.P. Gerard, R. Wyatt, H. Choe, C. Parolin, and N. Ruffing CD4-induced interaction of primary HIV-1 gp120 glycoproteins with the chemokine receptor CCR-5 Nature 384 6605 1996 179 183 [Epub 1996/11/14]
B. Chen, E.M. Vogan, H. Gong, J.J. Skehel, D.C. Wiley, and S.C. Harrison Structure of an unliganded simian immunodeficiency virus gp120 core Nature 433 7028 2005 834 841 [Epub 2005/02/25]
P.D. Kwong, R. Wyatt, J. Robinson, R.W. Sweet, J. Sodroski, and W.A. Hendrickson Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody Nature 393 6686 1998 648 659 [Epub 1998/06/26]
D.C. Chan, and P.S. Kim HIV entry and its inhibition Cell 93 5 1998 681 684 [Epub 1998/06/18]
R.E. Atchison, J. Gosling, F.S. Monteclaro, C. Franci, L. Digilio, and I.F. Charo Multiple extracellular elements of CCR5 and HIV-1 entry: dissociation from response to chemokines Science 274 5294 1996 1924 1926 [Epub 1996/12/13]
P.D. Bieniasz, R.A. Fridell, I. Aramori, S.S. Ferguson, M.G. Caron, and B.R. Cullen HIV-1-induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR-5 co-receptor EMBO J 16 10 1997 2599 2609 [Epub 1997/05/15]
L. Picard, G. Simmons, C.A. Power, A. Meyer, R.A. Weiss, and P.R. Clapham Multiple extracellular domains of CCR-5 contribute to human immunodeficiency virus type 1 entry and fusion J Virol 71 7 1997 5003 5011 [Epub 1997/07/01]
M. Samson, G. LaRosa, F. Libert, P. Paindavoine, M. Detheux, and G. Vassart The second extracellular loop of CCR5 is the major determinant of ligand specificity J Biol Chem 272 40 1997 24934 24941 [Epub 1997/10/06]
B.J. Doranz, Z.H. Lu, J. Rucker, T.Y. Zhang, M. Sharron, and Y.H. Cen Two distinct CCR5 domains can mediate coreceptor usage by human immunodeficiency virus type 1 J Virol 71 9 1997 6305 6314 [Epub 1997/09/01]
A. Brelot, N. Heveker, O. Pleskoff, N. Sol, and M. Alizon Role of the first and third extracellular domains of CXCR-4 in human immunodeficiency virus coreceptor activity J Virol 71 6 1997 4744 4751 [Epub 1997/06/01]
Z. Lu, J.F. Berson, Y. Chen, J.D. Turner, T. Zhang, and M. Sharron Evolution of HIV-1 coreceptor usage through interactions with distinct CCR5 and CXCR4 domains Proc Natl Acad Sci USA 94 12 1997 6426 6431 [Epub 1997/06/10]
T. Dragic, A. Trkola, S.W. Lin, K.A. Nagashima, F. Kajumo, and L. Zhao Amino-terminal substitutions in the CCR5 coreceptor impair gp120 binding and human immunodeficiency virus type 1 entry J Virol 72 1 1998 279 285 [Epub 1998/01/07]
G.E. Rabut, J.A. Konner, F. Kajumo, J.P. Moore, and T. Dragic Alanine substitutions of polar and nonpolar residues in the amino-terminal domain of CCR5 differently impair entry of macrophage- and dualtropic isolates of human immunodeficiency virus type 1 J Virol 72 4 1998 3464 3468 [Epub 1998/04/03]
L. Picard, D.A. Wilkinson, A. McKnight, P.W. Gray, J.A. Hoxie, and P.R. Clapham Role of the amino-terminal extracellular domain of CXCR-4 in human immunodeficiency virus type 1 entry Virology 231 1 1997 105 111 [Epub 1997/04/28]
M. Farzan, H. Choe, L. Vaca, K. Martin, Y. Sun, and E. Desjardins A tyrosine-rich region in the N terminus of CCR5 is important for human immunodeficiency virus type 1 entry and mediates an association between gp120 and CCR5 J Virol 72 2 1998 1160 1164 [Epub 1998/01/28]
J. Rucker, M. Samson, B.J. Doranz, F. Libert, J.F. Berson, and Y. Yi Regions in beta-chemokine receptors CCR5 and CCR2b that determine HIV-1 cofactor specificity Cell 87 3 1996 437 446 [Epub 1996/11/01]
B. Lee, M. Sharron, C. Blanpain, B.J. Doranz, J. Vakili, and P. Setoh Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function J Biol Chem 274 14 1999 9617 9626 [Epub 1999/03/27]
C.K. Lapham, J. Ouyang, B. Chandrasekhar, N.Y. Nguyen, D.S. Dimitrov, and H. Golding Evidence for cell-surface association between fusin and the CD4-gp120 complex in human cell lines Science 274 5287 1996 602 605 [Epub 1996/10/25]
A. McKnight, D. Wilkinson, G. Simmons, S. Talbot, L. Picard, and M. Ahuja Inhibition of human immunodeficiency virus fusion by a monoclonal antibody to a coreceptor (CXCR4) is both cell type and virus strain dependent J Virol 71 2 1997 1692 1696 [Epub 1997/02/01]
W.C. Olson, G.E. Rabut, K.A. Nagashima, D.N. Tran, D.J. Anselma, and S.P. Monard Differential inhibition of human immunodeficiency virus type 1 fusion, gp120 binding, and CC-chemokine activity by monoclonal antibodies to CCR5 J Virol 73 5 1999 4145 4155 [Epub 1999/04/10]
E.G. Cormier, M. Persuh, D.A. Thompson, S.W. Lin, T.P. Sakmar, and W.C. Olson Specific interaction of CCR5 amino-terminal domain peptides containing sulfotyrosines with HIV-1 envelope glycoprotein gp120 Proc Natl Acad Sci USA 97 11 2000 5762 5767 [Epub 2000/05/24]
E.G. Cormier, D.N. Tran, L. Yukhayeva, W.C. Olson, and T. Dragic Mapping the determinants of the CCR5 amino-terminal sulfopeptide interaction with soluble human immunodeficiency virus type 1 gp120-CD4 complexes J Virol 75 12 2001 5541 5549 [Epub 2001/05/18]
L. Wu, G. LaRosa, N. Kassam, C.J. Gordon, H. Heath, and N. Ruffing Interaction of chemokine receptor CCR5 with its ligands: multiple domains for HIV-1 gp120 binding and a single domain for chemokine binding J Exp Med 186 8 1997 1373 1381 [Epub 1997/10/23]
E.J. Platt, S.E. Kuhmann, P.P. Rose, and D. Kabat Adaptive mutations in the V3 loop of gp120 enhance fusogenicity of human immunodeficiency virus type 1 and enable use of a CCR5 coreceptor that lacks the amino-terminal sulfated region J Virol 75 24 2001 12266 12278 [Epub 2001/11/17]
T. Cardozo, T. Kimura, S. Philpott, B. Weiser, H. Burger, and S. Zolla-Pazner Structural basis for coreceptor selectivity by the HIV type 1 V3 loop AIDS Res Hum Retroviruses 23 3 2007 415 426 [Epub 2007/04/07]
A. Lopez de Victoria, C.A. Kieslich, A.K. Rizos, E. Krambovitis, and D. Morikis Clustering of HIV-1 subtypes based on gp120 V3 Loop electrostatic properties BMC Biophys 5 2012 3 [Epub 2012/02/09]
M.K. Lee, J. Heaton, and M.W. Cho Identification of determinants of interaction between CXCR4 and gp120 of a dual-tropic HIV-1DH12 isolate Virology 257 2 1999 290 296 [Epub 1999/05/18]
B. Labrosse, C. Treboute, A. Brelot, and M. Alizon Cooperation of the V1/V2 and V3 domains of human immunodeficiency virus type 1 gp120 for interaction with the CXCR4 receptor J Virol 75 12 2001 5457 5464 [Epub 2001/05/18]
R. Wyatt, P.D. Kwong, E. Desjardins, R.W. Sweet, J. Robinson, and W.A. Hendrickson The antigenic structure of the HIV gp120 envelope glycoprotein Nature 393 6686 1998 705 711 [Epub 1998/06/26]
C.C. Huang, M. Tang, M.Y. Zhang, S. Majeed, E. Montabana, and R.L. Stanfield Structure of a V3-containing HIV-1 gp120 core Science 310 5750 2005 1025 1028 [Epub 2005/11/15]
E.G. Cormier, and T. Dragic The crown and stem of the V3 loop play distinct roles in human immunodeficiency virus type 1 envelope glycoprotein interactions with the CCR5 coreceptor J Virol 76 17 2002 8953 8957 [Epub 2002/08/07]
C.C. Huang, S.N. Lam, P. Acharya, M. Tang, S.H. Xiang, and S.S. Hussan Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4 Science 317 5846 2007 1930 1934 [Epub 2007/09/29]
E. Schnur, E. Noah, I. Ayzenshtat, H. Sargsyan, T. Inui, and F.X. Ding The conformation and orientation of a 27-residue CCR5 peptide in a ternary complex with HIV-1 gp120 and a CD4-mimic peptide J Mol Biol 410 5 2011 778 797 [Epub 2011/07/19]
J.D. Reeves, N. Heveker, A. Brelot, M. Alizon, P.R. Clapham, and L. Picard The second extracellular loop of CXCR4 is involved in CD4-independent entry of human immunodeficiency virus type 2 J Gen Virol 79 Pt 7 1998 1793 1799 [Epub 1998/07/29]
B.J. Willett, K. Adema, N. Heveker, A. Brelot, L. Picard, and M. Alizon The second extracellular loop of CXCR4 determines its function as a receptor for feline immunodeficiency virus J Virol 72 8 1998 6475 6481 [Epub 1998/07/11]
F. Kajumo, D.A. Thompson, Y. Guo, and T. Dragic Entry of R5X4 and X4 human immunodeficiency virus type 1 strains is mediated by negatively charged and tyrosine residues in the amino-terminal domain and the second extracellular loop of CXCR4 Virology 271 2 2000 240 247 [Epub 2000/06/22]
D.J. Chabot, H. Chen, D.S. Dimitrov, and C.C. Broder N-linked glycosylation of CXCR4 masks coreceptor function for CCR5-dependent human immunodeficiency virus type 1 isolates J Virol 74 9 2000 4404 4413 [Epub 2001/02/07]
I. Thordsen, S. Polzer, and M. Schreiber Infection of cells expressing CXCR4 mutants lacking N-glycosylation at the N-terminal extracellular domain is enhanced for R5X4-dualtropic human immunodeficiency virus type-1 BMC Infect Dis 2 2002 31 [Epub 2002/12/20]
J. Wang, G.J. Babcock, H. Choe, M. Farzan, J. Sodroski, and D. Gabuzda N-linked glycosylation in the CXCR4 N-terminus inhibits binding to HIV-1 envelope glycoproteins Virology 324 1 2004 140 150 [Epub 2004/06/09]
E. De Clercq Recent advances on the use of the CXCR4 antagonist plerixafor (AMD3100, Mozobil) and potential of other CXCR4 antagonists as stem cell mobilizers Pharmacol Ther 128 3 2010 509 518 [Epub 2010/09/10]
A. Wood, and D. Armour The discovery of the CCR5 receptor antagonist, UK-427,857, a new agent for the treatment of HIV infection and AIDS Prog Med Chem 43 2005 239 271 [Epub 2005/04/27]
C.J. Hutchings, M. Koglin, and F.H. Marshall Therapeutic antibodies directed at G protein-coupled receptors mAbs 2 6 2010 594 606 [Epub 2010/09/25
B.M. Chain, M. Noursadeghi, M. Gardener, J. Tsang, and E. Wright HIV blocking antibodies following immunisation with chimaeric peptides coding a short N-terminal sequence of the CCR5 receptor Vaccine 26 45 2008 5752 5759 [Epub 2008/09/04]
T. Ishida, T. Joh, N. Uike, K. Yamamoto, A. Utsunomiya, and S. Yoshida Defucosylated anti-CCR4 monoclonal antibody (KW-0761) for relapsed adult T-cell leukemia-lymphoma: a multicenter phase II study J Clin Oncol 30 8 2012 837 842 [Epub 2012/02/09]
J.M. Jacobson, J.P. Lalezari, M.A. Thompson, C.J. Fichtenbaum, M.S. Saag, and B.S. Zingman Phase 2a study of the CCR5 monoclonal antibody PRO 140 administered intravenously to HIV-infected adults Antimicrob Agents Chemother 54 10 2010 4137 4142 [Epub 2010/07/28]
D. Smolarek, C. Hattab, G. Hassanzadeh-Ghassabeh, S. Cochet, C. Gutierrez, and A.G. de Brevern A recombinant dromedary antibody fragment (VHH or nanobody) directed against human Duffy antigen receptor for chemokines Cell Mol Life Sci 67 19 2010 3371 3387 [Epub 2010/05/12]
J.L. Galzi, M. Hachet-Haas, D. Bonnet, F. Daubeuf, S. Lecat, and M. Hibert Neutralizing endogenous chemokines with small molecules. Principles and potential therapeutic applications Pharmacol Ther 126 1 2010 39 55 [Epub 2010/02/02]
L. Skov, F.J. Beurskens, C.O. Zachariae, S. Reitamo, J. Teeling, and D. Satijn IL-8 as antibody therapeutic target in inflammatory diseases: reduction of clinical activity in palmoplantar pustulosis J Immunol 181 1 2008 669 679 [Epub 2008/06/21]
L. Gentilucci, R. De Marco, and L. Cerisoli Chemical modifications designed to improve peptide stability: incorporation of non-natural amino acids, pseudo-peptide bonds, and cyclization Curr Pharm Des 16 28 2010 3185 3203 [Epub 2010/08/07]
J.J. Nestor Jr. The medicinal chemistry of peptides Curr Med Chem 16 33 2009 4399 4418 [Epub 2009/10/20]
C.T. Veldkamp, J.J. Ziarek, F.C. Peterson, Y. Chen, and B.F. Volkman Targeting SDF-1/CXCL12 with a ligand that prevents activation of CXCR4 through structure-based drug design J Am Chem Soc 132 21 2010 7242 7243 [Epub 2010/05/13]
S.N. Lam, P. Acharya, R. Wyatt, P.D. Kwong, and C.A. Bewley Tyrosine-sulfate isosteres of CCR5 N-terminus as tools for studying HIV-1 entry Bioorgan Med Chem 16 23 2008 10113 10120 [Epub 2008/10/28]
C. Seibert, M. Cadene, A. Sanfiz, B.T. Chait, and T.P. Sakmar Tyrosine sulfation of CCR5 N-terminal peptide by tyrosylprotein sulfotransferases 1 and 2 follows a discrete pattern and temporal sequence Proc Natl Acad Sci USA 99 17 2002 11031 11036 [Epub 2002/08/10]
M. Hachet-Haas, K. Balabanian, F. Rohmer, F. Pons, C. Franchet, and S. Lecat Small neutralizing molecules to inhibit actions of the chemokine CXCL12 J Biol Chem 283 34 2008 23189 23199 [Epub 2008/06/17]
A. Sali, and T.L. Blundell Comparative protein modelling by satisfaction of spatial restraints J Mol Biol 234 3 1993 779 815 [Epub 1993/12/05]
B.R. Brooks, R.E. Bruccoleri, B.D. Olafson, D.J. States, S. Swaminathan, and M. Karplus CHARMM: a program for macromolecular energy, minimization, and dynamics calculations J Comp Chem 4 1993 187 217
D.J. Scholten, M. Canals, D. Maussang, L. Roumen, M.J. Smit, and M. Wijtmans Pharmacological modulation of chemokine receptor function Br J Pharmacol 165 6 2012 1617 1643 [Epub 2011/06/28]
C.H. Jen, K.L. Moore, and J.A. Leary Pattern and temporal sequence of sulfation of CCR5 N-terminal peptides by tyrosylprotein sulfotransferase-2: an assessment of the effects of N-terminal residues Biochemistry 48 23 2009 5332 5338 [Epub 2009/05/01]
