Human diseases; bone diseases; disease control; food composition; minerals; Tibet; diet; flours; calcium
Abstract :
[en] Kashin-Beck disease (KBD) is an endemic and chronic osteochondropathy. This disease principally occurs in the Tibet Autonomous Region and in several provinces of the People’s Republic of China. The etiology of the disease remains obscure although environmental factors are assumed to be involved. Diet, in particular, differentiates the rural community, affected by KBD, from the other communities (nomads and city-dwellers), who remain unaffected. In anticipation of a nutrition survey, this study aimed to measure the mineral content (Ca, P, Mg, Fe, Zn, Mn, Cu, Ni, Se, Al, Sr, Mo, Cd, As, Pb, Hg, Cr, and Co) of eight Tibetan staple foods and to compare the results against two food composition tables (FCTs). Foods were sampled in twenty households selected from both an endemic and a non-endemic area of rural Tibet. Ten minerals involved in bone metabolism were measured using atomic and molecular spectrometric methods. Results revealed that a very limited number of food/constituent pairs showed a variation in mineral composition during a single year of testing for a given region. In addition, results showed significant differences in mineral content between the endemic and the non-endemic area, especially for wheat flour. Following our analysis of the mineral content of the Tibetan food samples, results were statistically compared with similar foods listed in two food composition tables: the USDA National Nutrient Database (USDA Food Search for Windows, Version 1.0, database version SR23), and the China Food Composition Table (book 1, 2nd edition). More than 50 to 60% of p-values < 0.05 were highlighted, suggesting the inappropriateness of using FCTs as a reference for nutrition surveys in rural Tibet, and emphasizing the need for analysis of traditional foods. Differences were found to be more or less marked depending on the element considered, and calcium content seemed to show the greatest difference. Although it is obviously too early for definite conclusions to be reached (insufficient number of samples by food and insufficient number of foods analyzed), it seems that the present pilot-study indicates significant discrepancies between measured and tabulated values of the mineral content of certain foods. A more complete survey would therefore seem mandatory.
Research Center/Unit :
Gembloux Agro Bio Tech Center for Disease Control and Prevention of Tibet Autonomous Region Walloon Agricultural Research Center
Disciplines :
Endocrinology, metabolism & nutrition
Author, co-author :
DERMIENCE, Michael ; Université de Liège - ULiège > Chimie et bio-industries > Analyse, qual. et risques - Labo. de Chimie analytique
Mathieu, Françoise
Barthelemy, Jean-Paul ; Université de Liège - ULiège > Chimie et bio-industries > Analyse, qual. et risques - Labo. de Chimie analytique
Maesen, Philippe ; Université de Liège - ULiège > Gembloux Agro-Bio Tech
Romnee, Jean-Michel
De Maertelaer, Viviane
Denchen, Yangzom
Tsewang, Pema
Lognay, Georges ; Université de Liège - ULiège > Chimie et bio-industries > Analyse, qual. et risques - Labo. de Chimie analytique
Language :
English
Title :
The relevance of food composition data for nutrition surveys in rural Tibet: pilot study in the context of Kashin-Beck Disease
Alternative titles :
[en] The relevance of food composition data for nutrition surveys in rural Tibet: pilot study in the context of Kashin-Beck Disease
Publication date :
2013
Journal title :
Biotechnologie, Agronomie, Société et Environnement
ISSN :
1370-6233
eISSN :
1780-4507
Publisher :
Presses Agronomiques de Gembloux, Gembloux, Belgium
Volume :
17
Issue :
1
Pages :
32-42
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
Kashin-Beck Disease Fund asbl-vzw ULiège - Université de Liège
Funding text :
This study was made possible thanks to the close collaboration and the support of the Center for Disease Control and Prevention of Tibet Autonomous Region (P.R. China). We are in debt to CLSA Hong Kong who supported financially this study.
Association Nationale des Industries Alimentaires, 2009. Recommandations pratiques sur l'étiquetage nutritionnel, http://www.ania.net/ania/ressources/documents/3/E697FjGsS2P11mGO4cde6wMa.pdf, http://www.ania.net/ania/ressources/documents/3/E73BMgY9GEGGyr6D337y8Z21.pdf, (06.08.2012).
Baron R. & Tsouderos Y., 2002. In vitro effects of S12911-2 on osteoclast function and bone marrow macrophage differentiation. Eur. J. Pharmacol., 450(1), 11-17.
Church S.M., 2006. The history of food composition databases. Nutr. Bull., 31(1), 15-20.
Dang S. et al., 2004. Poor nutritional status of younger Tibetan children living at high altitudes. Eur. J. Clin. Nutr., 58, 938-946.
Egan M.B. et al., 2009. User-centred food composition data-analysis of user needs through the Use Case approach. Food Chem., 113(3), 804-807.
Gibson R.S., 1990. Principles of nutritional assessment. Oxford, UK: Oxford University Press.
Goyens P. et al., 2008. Nutritional issues in KBD endemic rural areas. In: Malaisse F. & Mathieu F., eds. Big bone disease. A multidisciplinary approach of Kashin-Beck disease in Tibet Autonomous Region (P.R. China). Gembloux, Belgium: Les Presses Agronomiques de Gembloux, 75-80.
Greenfield H. & Southgate D.A.T., 2003. Food composition data: production, management, and use. 2nd ed. Roma: Food and Agriculture Organization of the United Nations.
Haubruge É. et al., 2000. La maladie de Kashin-Beck et le milieu rural au Tibet: un problème agri-environnemental. Cah. Agric., 9, 117-124.
Haubruge É. et al., 2001. The prevalence of mycotoxins in Kashin-Beck disease. Int. Orthopaedics, 25(3), 159-161.
Jacotot B. & Le Parco J.-C., 1992. Nutrition et alimentation. 2e éd. Paris: Masson.
Li S. et al., 2009. Soil selenium concentration and Kashin-Beck disease prevalence in Tibet, China. Front. Environ. Sci. Eng. Chin., 3(1), 62-68.
Liquiang X. et al., 1991. Selenium in Kashin-Beck disease areas. Biol. Trace Elem. Res., 31(1), 1-9.
Malaisse F. et al., 2008. Framework. In: Malaisse F. & Mathieu F., eds. Big bone disease. A multidisciplinary approach of Kashin-Beck disease in Tibet Autonomous Region (P.R. China). Gembloux, Belgium: Les Presses Agronomiques de Gembloux, 19-36.
Marieb E.N., 2005. Anatomie et physiologies humaines. 6e ed. Paris: Pearson Education Limited.
Martin A., 2000. Apports nutritionnels conseillés pour la population française. 3e éd. Paris: Lavoisier Tec & Doc Éditions.
Mathieu F. & Hinsenkamp M., 2008a. Kashin-Beck disease. In: Malaisse F. & Mathieu F., eds. Big bone disease. A multidisciplinary approach of Kashin-Beck disease in Tibet Autonomous Region (P.R. China). Gembloux, Belgium: Les Presses Agronomiques de Gembloux, 11-18.
Mathieu F. et al., 2008b. Physical therapy study. In: Malaisse F. & Mathieu F., eds. Big bone disease. A multidisciplinary approach of Kashin-Beck disease in Tibet Autonomous Region (P.R. China). Gembloux, Belgium: Les Presses Agronomiques de Gembloux, 61-64.
Matsumoto H., Silverton S.F., Debolt K. & Shapiro I.M., 1991. Superoxide dismutase and catalase activities in the growth cartilage: relationship between oxidoreductase activity and chondrocyte maturation. J. Bone Miner. Res., 6(6), 569-574.
Miller J.N. & Miller J.C., 2005. Statistics and chemometrics for analytical chemistry. 5th ed. Harlow, UK: Pearson Education Limited.
Moon C.S. et al., 1996. A comparison of the food composition table-based estimates of dietary element intake with the values obtained by inductively coupled plasma atomic emission spectrometry: an experience in a Japanese population. J. Trace Elem. Med. Biol., 10(4), 237-244.
Moreno-Reyes R. et al., 1998. Kashin-Beck osteoarthropathy in rural Tibet in relation to selenium and iodine status. N. Engl. J. Med., 339(16), 1112-1120.
Moreno-Reyes R. et al., 2001. Selenium deficiency-induced growth retardation is associated with an impaired bone metabolism and osteopenia. J. Bone Miner. Res., 16(8), 1556-1563.
National Institute of Nutrition and Food Safety China CDC, 2009. China food composition. 2nd ed. Beijing: Peking University Medical Press.
Pi M. & Quarles L.D., 2004. A novel cation-sensing mechanism in osteoblasts is a molecular target for strontium. J. Bone Miner. Res., 19(5), 862-869.
Sarazin M., Alexandre C. & Thomas T., 2000. Influence of trace element, protein, lipid, carbohydrate, and vitamin intakes on bone metabolism. Rev. Rhum., 67(7), 486-497.
Sctrick L., 1991. L'oligothérapie exactement. Limoges, France: Éditions Roger Jollois.
Shi Z. et al., 2009. Butenolide induced cytotoxicity by disturbing the prooxidant-antioxidant balance, and antioxidants partly quench in human chondrocytes. Toxicol. in Vitro, 23(1), 99-104.
Suetens C. et al., 2001. Epidemiological support for a multifactorial aetiology of Kashin-Beck disease in Tibet. Int. Orthopaedics, 25(3), 180-187.
US Department of Agriculture, Agricultural Research Service, 2010. USDA national nutrient database for standard reference, Release 23. Nutrient data laboratory home page, http://www.ars.usda.gov/ba/bhnrc/ndl, (09/07/10).
Wang S. et al., 2008. Detection of serum proteomic changes and discovery of serum biomarkers for Kashin-Beck disease using surface-enhanced laser desorption ionization mass spectrometry (SELDI-TOF MS). J. Bone Miner. Metab., 26(4), 385-393.
Wang W.Z. et al., 2009. Comparative analysis of gene expression profiles between the normal human cartilage and the one with endemic osteoarthritis. Osteoarthritis Cartilage, 17(1), 83-90.
Yang C. et al., 1993. Selenium deficiency and fulvic acid supplementation induces fibrosis of cartilage and disturbs subchondral ossification in knee joints of mice: an animal model study of Kashin-Beck disease. Virchows Archiv, 423(6), 483-491.
