Reference : Response to novelty as a predictor for drug effects: the pitfalls of some correlation...
Scientific journals : Letter to the editor
Human health sciences : Psychiatry
Human health sciences : Pharmacy, pharmacology & toxicology
Social & behavioral sciences, psychology : Neurosciences & behavior
Response to novelty as a predictor for drug effects: the pitfalls of some correlational studies
Quertemont, Etienne mailto [Université de Liège - ULiège > Département des sciences cognitives > Psychologie quantitative >]
Brabant, Christian mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biochimie et physiologie humaine et pathologique >]
Tirelli, Ezio mailto [Université de Liège - ULiège > Département des sciences cognitives > Neuroscience comportementale et psychopharmacologie expér. >]
Springer Verlag
Yes (verified by ORBi)
[en] Novelty ; Addiction ; Cocaine
[en] In recent years, an individual's response to novelty has been postulated to predict its response to drugs of abuse and particularly to their addictive properties (Piazza et al. 1990). The hypothesis of a relationship between the response to novelty and the effects of addictive drugs was supported by a number of animal studies that reported correlations between responses to a novel environment and various effects of drugs, such as their locomotor stimulant effects, their reinforcing action or their propensity to be self-administered (Piazza et al. 1990; Klebaur et al. 2001; Carey et al. 2003; Shimosato and Watanabe 2003). Most of these studies concluded that an animal's response to novelty predicts its subsequent response to drug administration. However, correlational studies are sometimes hampered by methodological and statistical weaknesses that preclude a proper interpretation of the results. The two most frequent weaknesses are the lack of consideration for the correlation in the control group and the calculation of spurious correlations.
Centre de Neurosciences Cognitives et Comportementales
Fonds de la Recherche Scientifique (Communauté française de Belgique) - F.R.S.-FNRS
Researchers ; Professionals

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